Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human CXCR1 Protein, hFc Tag
Artikelnummer: DIM-PME100820.10
Recombinant human CXCR1 protein with C-terminal human Fc tag. CXCR1(Met1-Lys39) hFc(Glu99-Ala330), Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate...
| Schlagworte: | C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 30.6 kD |
ab 151,00 €
Human MST1R Protein, hFc Tag
Artikelnummer: DIM-PME100821.10
Recombinant Human MST1R Protein with C-terminal Human Fc tag. MST1R(Glu25-Thr957) hFc(Glu99-Ala330), Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration...
| Schlagworte: | CD136, CDw136, NPCA3, PTK8, RON |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 125.9 kD |
ab 200,00 €
Human CEACAM6 Protein, His Tag
Artikelnummer: DIM-PME100822.10
Recombinant human CEACAM6 protein with C-terminal 6×His tag. CEACAM6(Lys35-Gly320) 6×His tag, Protein function: Cell surface glycoprotein that plays a role in cell adhesion and tumor progression (PubMed:2803308, PubMed:2022629, PubMed:1378450, PubMed:8776764, PubMed:11590190, PubMed:10910050, PubMed:14724575,...
| Schlagworte: | CD66c, CEAL, NCA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 32.1 kD |
ab 124,00 €
Human CCR4 (1-39) Protein, hFc Tag
Artikelnummer: DIM-PME100824.10
Recombinant Human CCR4 with C-terminal human Fc tag. CCR4(Met1-Glu39) hFc(Glu99-Ala330), Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second...
| Schlagworte: | CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, HGCN:14099, K5-5 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 30.6 kD |
ab 105,00 €
Human CCR7 Protein, hFc Tag
Artikelnummer: DIM-PME100825.10
Recombinant Human CCR7 with C-terminal human Fc tag. CCR7(Gln25-Trp59) hFc(Glu99-Ala330), Protein function: Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. [The UniProt Consortium]
| Schlagworte: | BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 30.2 kD |
ab 114,00 €
Human CCR9 Protein, hFc Tag
Artikelnummer: DIM-PME100826.10
Recombinant Human CCR9 with C-terminal human Fc tag. CCR9(Met1-Ser48) hFc(Glu99-Ala330), Protein function: Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level. [The UniProt Consortium]
| Schlagworte: | CC-CKR-9, CDw199, GPR-9-6, GPR28 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 31.6 kD |
ab 105,00 €
Human CD200R1 Protein, His Tag
Artikelnummer: DIM-PME100827.10
Recombinant Human CD200R1 Protein with C-terminal 6×His tag. CD200R1(Met29-Leu243) 6×His tag, Protein function: Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide...
| Schlagworte: | CD200R, HCRTR2, MOX2R, OX2R |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 25.0 kD |
ab 151,00 €
Human CD3E Protein, hFc Tag
Artikelnummer: DIM-PME100828.10
Recombinant human CD3E protein with C-terminal human Fc tag. CD3E(Asp23-Asp126) hFc(Glu99-Ala330), Protein function: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-...
| Schlagworte: | CD3e, T3E |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 37.9 kD |
ab 105,00 €
Human CD73 Protein, hFc Tag
Artikelnummer: DIM-PME100829.10
Recombinant Human CD73 Protein with C-terminal human Fc tag. CD73(Trp27-Ser549) hFc(Glu99-Ala330), Protein function: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. [The UniProt Consortium]
| Schlagworte: | CALJA, CD73, E5NT, eN, eNT, NT, NT5, NTE |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 84.1 kD |
ab 200,00 €
Human C5AR1 Protein, hFc Tag
Artikelnummer: DIM-PME100830.10
Recombinant Human C5AR1 Protein with C-terminal human Fc tag. C5AR1(Met1-Asp37) hFc(Glu99-Ala330), Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand...
| Schlagworte: | C5A, C5AR, C5R1, CD88 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 30.4 kD |
ab 151,00 €
Human CEACAM1 Protein,His Tag
Artikelnummer: DIM-PME100831.10
Recombinant human CEACAM1 protein with C-terminal 6×His tag. CEACAM1(Gln35-Gly428) 6×His tag, Protein function: [Isoform 1]: Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an...
| Schlagworte: | BGP, BGP1, BGPI |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 44.1 kD |
ab 114,00 €
Human CLEC2D Protein, hFc Tag
Artikelnummer: DIM-PME100832.10
Recombinant Human CLEC2D Protein with N-terminal human Fc tag. hFc(Glu99-Ala330) CLEC2D(Arg60-Val191), Protein function: Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:20843815, PubMed:16339513). Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656)....
| Schlagworte: | CLAX, LLT1, OCIL |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 41.5 kD |
ab 124,00 €