Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-FZD10(tabituximab biosimilar) mAb
Artikelnummer: DIM-BME100185.100
Protein function: Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second...
| Schlagworte: | Anti-CD350, Anti-FZ-10, Anti-Fz10, Anti-FzE7, Anti-hFz10, Anti-FZD10(tabituximab biosimilar) mAb |
| Wirt: | Chimeric |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-ALPP(SGN-ALPV biosimilar) mAb
Artikelnummer: DIM-BME100186.100
| Schlagworte: | Anti-PLAP, Anti-ALPP(SGN-ALPV biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-GPRC5D(LM305 biosimilar) mAb
Artikelnummer: DIM-BME100187.100
| Schlagworte: | Anti-GPRC5D, Anti-GPRC5D(LM305 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-STEAP1(Vandortuzumab biosimilar) mAb
Artikelnummer: DIM-BME100188.100
Protein function: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. [The UniProt Consortium]
| Schlagworte: | Anti-PRSS24, Anti-STEAP, Anti-STEAP1(Vandortuzumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-EPCAM(IMC001 biosimilar) mAb
Artikelnummer: DIM-BME100189.100
Protein function: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells...
| Schlagworte: | Anti-GA733-2, Anti-M1S2, Anti-M4S1, Anti-MIC18, Anti-TACSTD1, Anti-TROP1, Anti-EPCAM(IMC001 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-B7-H4(AZD-8205 biosimilar) mAb
Artikelnummer: DIM-BME100190.100
Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in the suppression of...
| Schlagworte: | Anti-VTCN1, Anti-B7-H4(AZD-8205 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-ROR1(NBE 002 biosimilar) mAb
Artikelnummer: DIM-BME100191.100
Protein function: Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443, PubMed:27162350). In inner ear,...
| Schlagworte: | Anti-NTRKR1, Anti-ROR1(NBE 002 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-B7-H4(XMT-1660 biosimilar) mAb
Artikelnummer: DIM-BME100192.100
Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in the suppression of...
| Schlagworte: | Anti-VTCN1, Anti-B7-H4(XMT-1660 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-GPRC5D(LBL-034 biosimilar) mAb
Artikelnummer: DIM-BME100193.100
| Schlagworte: | Anti-GPRC5D, Anti-GPRC5D(LBL-034 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-GPNMB(glembatumumab biosimilar) mAb
Artikelnummer: DIM-BME100194.100
Protein function: Could be a melanogenic enzyme. [The UniProt Consortium]
| Schlagworte: | Anti-HGFIN, Anti-NMB, Anti-GPNMB(glembatumumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CEACAM5(tusamitamab biosimilar) mAb
Artikelnummer: DIM-BME100195.100
Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6...
| Schlagworte: | Anti-CEA, Anti-CEACAM5(tusamitamab biosimilar) mAb |
| Wirt: | Chimeric |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-GPRC5D and CD3(LBL-034 biosimilar) BsAb
Artikelnummer: DIM-BME100196.100
| Schlagworte: | Anti-GPRC5D, Anti-CD3, Anti-GPRC5D and CD3(LBL-034 biosimilar) BsAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €