Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human IFNAR1 Protein, hFc Tag
Artikelnummer: DIM-PME100773.10
Recombinant Human IFNAR1 Protein with C-terminal human Fc tag. IFNAR1(Lys28-Lys436) hFc(Glu99-Ala330), Protein function: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986)....
| Schlagworte: | AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 73.3 kD |
ab 176,00 €
Human CD106 Protein, His Tag
Artikelnummer: DIM-PME100774.10
Recombinant human CD106 protein with C-terminal 6×His tag. CD106(Phe25-Glu698) 6×His tag, Protein function: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha- 4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal...
| Schlagworte: | VCAM1, V-CAM 1, VCAM-1, INCAM-100 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 75.1 kD |
ab 176,00 €
Human TFRC Protein, His Tag
Artikelnummer: DIM-PME100775.10
Recombinant human TFRC protein with N-terminal 6×His tag. 6×His tag TFRC(Cys89-Phe760), Protein function: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed:26214738). Endosomal acidification leads to iron release. The...
| Schlagworte: | TR, TfR, TfR1, Trfr, T9, p90, CD71 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 76 kD |
ab 151,00 €
Human CD52 Protein, hFc Tag
Artikelnummer: DIM-PME100776.10
Recombinant human CD52 protein with C-terminal human Fc tag. CD52(Gly25-Ser36) hFc(Glu99-Ala330), Protein function: May play a role in carrying and orienting carbohydrate, as well as having a more specific role. [The UniProt Consortium]
| Schlagworte: | CDW52, HE5, CAMPATH-1 antigen |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 27.3 kD |
ab 151,00 €
Human TGFBR1 Protein, hFc Tag
Artikelnummer: DIM-PME100777.10
Recombinant human TGFBR1 protein with C-terminal Human Fc tag. TGFBR1(Leu34-Leu126) hFc(Glu99-Ala330), Protein function: Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3....
| Schlagworte: | AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, tbetaR-I, TBR-i, TBRI, TGFR-1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 36.3 kD |
ab 176,00 €
Human QSOX1 Protein, His Tag
Artikelnummer: DIM-PME100778.10
Recombinant human QSOX1 protein with C-terminal 6×His tag. QSOX1(Ala30-Ser706) 6×His tag, Protein function: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide (PubMed:17331072, PubMed:18393449, PubMed:23704371, PubMed:30367560,...
| Schlagworte: | hQSOX, Quiescin Q6 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 75.9 kD |
ab 176,00 €
Human RSPO1(21-263) Protein, His Tag
Artikelnummer: DIM-PME100779.10
Recombinant human RSPO1(21-263) protein with C-terminal 6×His tag. RSPO1(Ser21-Ala263) 6×His tag, Protein function: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors (PubMed:29769720). Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and...
| Schlagworte: | R-spondin-1, hRspo1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 27.6 kD |
ab 176,00 €
Human RSPO1(21-146) Protein, hFc Tag
Artikelnummer: DIM-PME100780.10
Recombinant human RSPO1(21-146) protein with C-terminal human Fc tag. RSPO1(Ser21-Ala146) hFc(Glu99-Ala330), Protein function: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors (PubMed:29769720). Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with...
| Schlagworte: | R-spondin-1, hRspo1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.9 kD |
ab 151,00 €
Human CD19 Protein, mFc Tag
Artikelnummer: DIM-PME100781.10
Recombinant human CD19 protein with C-terminal mouse Fc tag. CD19(Pro20-Lys291) mFc(Pro99-Lys330), Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to...
| Schlagworte: | B4, CVID3, MGC12802 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 56.3 kD |
ab 183,00 €
Human CLDN2 Protein, hFc Tag
Artikelnummer: DIM-PME100782.10
Recombinant human CLDN2 protein with C-terminal human Fc tag. CLDN2(Ser29-Gln78) hFc(Glu99-Ala330), Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [The UniProt Consortium]
| Schlagworte: | Claudin-2, SP82 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 31.4 kD |
ab 176,00 €
Human AGR2 Protein, hFc Tag
Artikelnummer: DIM-PME100783.10
Recombinant human AGR2 protein with C-terminal human Fc tag. AGR2(Arg21-Leu175) hFc(Glu99-Ala330), Protein function: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell...
| Schlagworte: | AG-2, hAG-2, HPC8 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 44.0 kD |
ab 151,00 €
Human MCEMP1 Protein, hFc Tag
Artikelnummer: DIM-PME100784.10
Recombinant human MCEMP1 protein with N-terminal human Fc tag. hFc(Glu99-Ala330) MCEMP1(Lys107-Gln187)
| Schlagworte: | Mast cell-expressed membrane protein 1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 35.5 kD |
ab 151,00 €