Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human ANXA1 Protein, His Tag
Artikelnummer: DIM-PME100760.10
Recombinant human ANXA1 Protein with C-terminal 6×His tag. ANXA1(Ala2-Asn346) 6×His tag, Protein function: Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity (PubMed:8425544). Plays a role in...
| Schlagworte: | Annexin A1, p35, ANX1, LPC1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.4 kD |
ab 151,00 €
Human RNF43 Protein, hFc Tag
Artikelnummer: DIM-PME100761.10
Recombinant human RNF43 protein with C-terminal human Fc tag. RNF43(Glu43-Tyr197) hFc(Glu99-Ala330), Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components...
| Schlagworte: | RNF124, SSPCS, URCC |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.4 kD |
ab 151,00 €
Human RNF43 Protein, mFc Tag
Artikelnummer: DIM-PME100762.10
Recombinant human RNF43 protein with C-terminal mouse Fc tag. RNF43(Glu43-Tyr197) mFc(Pro99-Lys330), Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components...
| Schlagworte: | RNF124, SSPCS, URCC |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.4 kD |
ab 151,00 €
Human CLDN5 Protein, hFc Tag
Artikelnummer: DIM-PME100763.10
Recombinant human CLDN5 protein with C-terminal human Fc tag. CLDN5(Met29-Arg81) hFc(Glu99-Ala330), Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space. [The UniProt Consortium]
| Schlagworte: | Claudin-5, TMDVCF, AWAL, TMVCF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 32.1 kD |
ab 176,00 €
Human ITGAX and ITGB2 Heterodimer Protein, His Tag and...
Artikelnummer: DIM-PME100764.10
Heterodimer protein contains recombinant human ITGAX protein with C-terminal 6×His tag and human ITGB2 protein with C-terminal human Fc tag. ITGAX(Phe20-Pro1107) 6×His tag and ITGB2(Gln23-Asn700) hFc(Glu99-Ala330), Protein function: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence...
| Schlagworte: | Integrin alpha-XandIntegrin beta-2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 120.6/ kD |
ab 183,00 €
Human TIMP4 Protein, hFc Tag
Artikelnummer: DIM-PME100765.10
Recombinant human TIMP4 protein with C-terminal human Fc tag. TIMP4(Cys30-Pro224) hFc(Glu99-Ala330), Protein function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9. [The...
| Schlagworte: | TIMP-4 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 48.6 kD |
ab 183,00 €
Human Trop2 Protein, His Tag
Artikelnummer: DIM-PME100766.10
Recombinant human Trop2 protein with C-terminal 6×His tag. TROP2(His27-Thr274) 6×His tag, Protein function: May function as a growth factor receptor. [The UniProt Consortium]
| Schlagworte: | TACSTD2, GA733-1, M1S1, TROP2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 28.7 kD |
ab 151,00 €
Human CD72 Protein, hFc Tag
Artikelnummer: DIM-PME100767.10
Recombinant human CD72 protein with N-terminal human Fc tag. hFc(Glu99-Ala330) CD72(Arg117-Asp359), Protein function: Plays a role in B-cell proliferation and differentiation. [The UniProt Consortium]
| Schlagworte: | Lyb-2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 54.2 kD |
ab 176,00 €
Human B7-H7 Protein, hFc Tag
Artikelnummer: DIM-PME100768.10
Recombinant human B7-H7 protein with C-terminal human Fc tag. B7-H7(Ile23-Asn344) hFc(Glu99-Ala330), Protein function: Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. [The...
| Schlagworte: | HHLA2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 63.1 kD |
ab 176,00 €
Human FGF21 Protein, hFc Tag
Artikelnummer: DIM-PME100769.10
Recombinant human FGF21 protein with C-terminal human Fc tag. FGF21(His29-Ser209) hFc(Glu99-Ala330), Protein function: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. [The...
| Schlagworte: | Fibroblast growth factor 21, FGF-21 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 45.5 kD |
ab 151,00 €
Human TPSAB1 Protein, His Tag
Artikelnummer: DIM-PME100770.10
Recombinant human TPSAB1 Protein with C-terminal 6×His tag. TPSAB1(Ala19-Pro275) 6×His tag, Protein function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large...
| Schlagworte: | Tryptase-1, Tryptase I, Tryptase alpha-1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 29.6 kD |
ab 151,00 €
Human ADAMTS1 Protein, His Tag
Artikelnummer: DIM-PME100771.10
Recombinant human ADAMTS1 Protein with C-terminal 6×His tag. ADAMTS1(Leu50-Ser967) 6×His tag, Protein function: Cleaves aggrecan, a cartilage proteoglycan, at the '1938- Glu-, -Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity....
| Schlagworte: | ADAM-TS 1, ADAM-TS1, ADAMTS-1, METH-1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 101.1 kD |
ab 176,00 €