Produkte von DIMA Biotech

DIMA

DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her. 

Mehr Informationen unter: www.dimabio.com

Zu den Katalogen von DIMA Biotech

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Human IL1R2 Protein, His Tag
Human IL1R2 Protein, His Tag

Artikelnummer: DIM-PME100748.10

Recombinant human IL1R2 protein with C-terminal 6×His tag. IL1R2(Phe14-Glu343) 6×His tag, Protein function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through...
Schlagworte: IL-1RT2, IL1RB, CDw121b, IL-1R-beta, CD121b
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 38.6 kD
ab 105,00 €
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Human EMCN Protein, hFc Tag
Human EMCN Protein, hFc Tag

Artikelnummer: DIM-PME100749.10

Recombinant human EMCN protein with C-terminal human Fc tag. EMCN(Asn19-Ser190) hFc(Glu99-Ala330), Protein function: Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the...
Schlagworte: Endomucin, MUC-14
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 43.9 kD
ab 105,00 €
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Human PRLR Protein, hFc Tag
Human PRLR Protein, hFc Tag

Artikelnummer: DIM-PME100750.10

Recombinant human PRLR protein with C-terminal human Fc tag. PRLR(Gln25-Asp234) hFc(Glu99-Ala330), Protein function: This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and...
Schlagworte: Prolactin receptor, PRL-R
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 50.5 kD
ab 105,00 €
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Human CD142 Protein, hFc Tag
Human CD142 Protein, hFc Tag

Artikelnummer: DIM-PME100751.10

Recombinant human CD142 protein with C-terminal human Fc tag. CD142(Ser33-Glu251) hFc(Glu99-Ala330), Protein function: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal...
Schlagworte: TF, Coagulation factor III, F3
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 50.9 kD
ab 176,00 €
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Human TNFSF15 Protein, hFc Tag
Human TNFSF15 Protein, hFc Tag

Artikelnummer: DIM-PME100752.10

Recombinant human TNFSF15 protein with N-terminal human Fc tag. hFc(Glu99-Ala330) TNFSF15(Leu72-Leu251), Protein function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. [The...
Schlagworte: TL1, VEGI
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 46.6 kD
ab 105,00 €
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Human ADAM15 Protein, hFc Tag
Human ADAM15 Protein, hFc Tag

Artikelnummer: DIM-PME100753.10

Recombinant human ADAM15 protein with C-terminal human Fc tag. ADAM15(Leu18-Thr696) hFc(Glu99-Ala330), Protein function: Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic...
Schlagworte: ADAM 15, MDC-15
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 100.0 kD
ab 176,00 €
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Human MMP9(20-707) Protein, His Tag
Human MMP9(20-707) Protein, His Tag

Artikelnummer: DIM-PME100754.10

Recombinant human MMP9(20-707) protein with C-terminal 6×His tag. MMP9(Ala20-Asp707) 6×His tag, Protein function: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-, -Leu bond. Cleaves type...
Schlagworte: CLG4B, GELB, MANDP2, MMP-9
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 77.2 kD
ab 176,00 €
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Human B7-H3 Protein, mFc Tag
Human B7-H3 Protein, mFc Tag

Artikelnummer: DIM-PME100755.10

Recombinant human B7-H3 protein with C-terminal mouse Fc tag. B7-H3(Gly27-Thr461) mFc(Pro99-Lys330), Protein function: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for...
Schlagworte: B7H3, CD276, 4Ig-B7-H3
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 72.8 kD
ab 105,00 €
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Human CLEC4C Protein, hFc Tag
Human CLEC4C Protein, hFc Tag

Artikelnummer: DIM-PME100756.10

Recombinant human CLEC4C protein with N-terminal human Fc tag. hFc(Glu99-Ala330) CLEC4C(Asn45-Ile213), Protein function: Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PubMed:11748283, PubMed:21880719, PubMed:25995448). Specifically recognizes non-sialylated...
Schlagworte: BDCA-2, CD303
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 46.1 kD
ab 105,00 €
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Human GPR55(1-21) Protein, hFc Tag
Human GPR55(1-21) Protein, hFc Tag

Artikelnummer: DIM-PME100757.10

Recombinant human GPR55(1-21) protein with C-terminal human Fc tag. GPR55(Met1-Thr21) hFc(Glu99-Ala330), Protein function: May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L-alpha- lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via...
Schlagworte: G-protein coupled receptor 55
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 28.5 kD
ab 105,00 €
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Human SPARC Protein, hFc Tag
Human SPARC Protein, hFc Tag

Artikelnummer: DIM-PME100758.10

Recombinant human SPARC protein with N-terminal human Fc tag. hFc(Glu99-Ala330) SPARC(Ala18-Ile303), Protein function: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell...
Schlagworte: BM-40, Osteonectin, ON
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 58.8 kD
ab 105,00 €
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Human LIV-1 Protein, His Tag
Human LIV-1 Protein, His Tag

Artikelnummer: DIM-PME100759.10

Recombinant human LIV-1 Protein with C-terminal 6×His tag. LIV-1(Phe29-Trp325) 6×His tag, Protein function: May act as a zinc-influx transporter. [The UniProt Consortium]
Schlagworte: LIV1, SLC39A6, ZIP-6
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 34.4 kD
ab 200,00 €
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