Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human RET Protein, His Tag
Artikelnummer: DIM-PME100736.10
Recombinant human RET protein with C-terminal 6×His tag. RET(Leu29-Arg635) 6×His tag, Protein function: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived...
| Schlagworte: | Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 68.6 kD |
ab 120,00 €
Human IFNAR1 Protein, mFc Tag
Artikelnummer: DIM-PME100737.10
Recombinant human IFNAR1 Protein with C-terminal Mouse Fc tag. IFNAR1(Lys28-Lys436) mFc(Pro99-Lys330), Protein function: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986)....
| Schlagworte: | Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, CRF2-1, Type I interferon receptor 1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 73 kD |
ab 176,00 €
Human MDK Protein, hFc Tag
Artikelnummer: DIM-PME100738.10
Recombinant human MDK protein with C-terminal human Fc tag. MDK(Val21-Asp143) hFc(Glu99-Ala330), Protein function: Secreted protein that functions as cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non- proteoglycan receptors (PubMed:18469519, PubMed:12573468,...
| Schlagworte: | Midkine, MK, ARAP, Midgestation and kidney protein, Neurite outgrowth-promoting factor 2, Neurite outgrowth-promoting protein |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.6 kD |
ab 120,00 €
Human IL31 Protein, hFc Tag
Artikelnummer: DIM-PME100739.10
Recombinant human IL31 protein with C-terminal human Fc tag. IL31(Ser24-Thr164) hFc(Glu99-Ala330), Protein function: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR (PubMed:15184896). May function in skin immunity (PubMed:15184896). Enhances myeloid...
| Schlagworte: | Interleukin-31, IL-31 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 42 kD |
ab 105,00 €
Human CLEC2D Protein, His Tag
Artikelnummer: DIM-PME100740.10
Recombinant human CLEC2D protein with C-terminal 6×His tag. CLEC2D(Arg60-Val191) 6×His tag, Protein function: Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:20843815, PubMed:16339513). Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656). Inhibits bone...
| Schlagworte: | C-type lectin domain family 2 member D, Lectin-like NK cell receptor, LLT-1, Osteoclast inhibitory lectin |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 16.2 kD |
ab 105,00 €
Human ADGRE2 Protein, His Tag
Artikelnummer: DIM-PME100741.10
Recombinant human ADGRE2 protein with C-terminal 7×His tag. ADGRE2(Gln24-Thr537) 7×His tag, Protein function: Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages,...
| Schlagworte: | Adhesion G protein-coupled receptor E2, EGF-like module receptor 2, EGF-like module-containing mucin-like hormone... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 57.2 kD |
ab 105,00 €
Human ADAMTS13 Protein, His Tag
Artikelnummer: DIM-PME100742.10
Recombinant human ADAMTS13 protein with C-terminal 6×His tag. ADAMTS13(Gln34-Thr1427) 6×His tag, Protein function: Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation. [The UniProt Consortium]
| Schlagworte: | A disintegrin and metalloproteinase with thrombospondin motifs 13 , ADAM-TS 13, ADAM-TS13, ADAMTS-13, vWF-CP,... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 150.8 kD |
ab 176,00 €
Human CD63 Protein, hFc Tag
Artikelnummer: DIM-PME100743.10
Recombinant human CD63 protein with C-terminal human Fc tag. CD63(Ala103-Val203) hFc(Glu99-Ala330), Protein function: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the...
| Schlagworte: | CD63 antigen, Granulophysin, LAMP-3, Limp1, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen,... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 37.7 kD |
ab 105,00 €
Human LIF Protein, hFc Tag
Artikelnummer: DIM-PME100744.10
Recombinant human LIF protein with C-terminal human Fc tag. LIF(Ser23-Phe202) hFc(Glu99-Ala330), Protein function: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of...
| Schlagworte: | Leukemia inhibitory factor, D factor, MLPLI, Emfilermin |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 46 kD |
ab 105,00 €
Human LILRB2 Protein, His Tag
Artikelnummer: DIM-PME100745.10
Recombinant human LILRB2 protein with C-terminal 6×His tag. LILRB2(Gln22-Val461) 6×His tag, Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:11169396, PubMed:12853576, PubMed:16455647, PubMed:20448110, PubMed:27859042). Involved...
| Schlagworte: | LIR-2, ILT-4, MIR-10, CD85d |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 48.6 kD |
ab 176,00 €
Human IL1RAP Protein, His Tag
Artikelnummer: DIM-PME100746.10
Recombinant human IL1RAP protein with C-terminal 6×His tag. IL1RAP(Ser21-Glu359) 6×His tag, Protein function: Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which...
| Schlagworte: | IL-1RAcP, IL-1R3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.9 kD |
ab 105,00 €
Human RAGE Protein, His Tag
Artikelnummer: DIM-PME100747.10
Recombinant human RAGE protein with C-terminal 6×His tag. RAGE(Thr27-Thr340) 6×His tag, Protein function: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a...
| Schlagworte: | AGER |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 34.2 kD |
ab 120,00 €