Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human HSP90AA1 Protein, His Tag
Artikelnummer: DIM-PME100712.10
Recombinant human HSP90AA1 protein with N-terminal 6×His tag. 6×His tag HSP90AA1(Pro2-Asp732), Protein function: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a...
| Schlagworte: | HSP90AA1, HSP86, LAP-2, HSP90A, HSPC1, HSPCA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 85.4 kD |
ab 120,00 €
Human HPSE Protein, His Tag
Artikelnummer: DIM-PME100713.10
Recombinant human HPSE protein with C-terminal 6×His tag. HPSE(Gln36-Ile543) 6×His tag, Protein function: Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively...
| Schlagworte: | Heparanase, Hpa1, HEP, HPA, HPA1, HPR1, HPSE1, HSE1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 58.4 kD |
ab 114,00 €
Human HSD17B10 Protein, S Tag
Artikelnummer: DIM-PME100714.10
Recombinant human HSD17B10 protein with N-terminal S tag. S tag HSD17B10(Ala2-Pro261), Protein function: Mitochondrial dehydrogenase involved in pathways of fatty acid, branched-chain amino acid and steroid metabolism (PubMed:9553139, PubMed:10600649, PubMed:12917011, PubMed:20077426, PubMed:18996107,...
| Schlagworte: | MHBD, Type II HADH, ERAB, HADH2, MRPP2, SCHAD, SDR5C1, XH98G2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 28.5 kD |
ab 120,00 €
Human SCUBE2(441-659) Protein, hFc Tag
Artikelnummer: DIM-PME100715.10
Recombinant human SCUBE2(441-659) protein with C-terminal human Fc tag. SCUBE2(Asp441-Asn659 ) hFc(Glu99-Ala330), Protein function: Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the...
| Schlagworte: | CEGP1, Scube/You |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 50.2 kD |
ab 120,00 €
Human CD235A Protein, hFc Tag
Artikelnummer: DIM-PME100716.10
Recombinant human CD235A protein with C-terminal human Fc tag. CD235A(His28-Glu91) hFc(Glu99-Ala330), Protein function: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to...
| Schlagworte: | Glycophorin-A, CD235a, PAS-2, GYPA, GPA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 33.3 kD |
ab 105,00 €
Human ITGA2 and ITGB1 Heterodimer Protein, His Tag and...
Artikelnummer: DIM-PME100717.10
Recombinant human ITGA2 protein with C-terminal 6×His tag and human ITGB1 protein with C-terminal human Fc tag. ITGA2(Tyr30-Thr1132) 6×His tag and ITGB1(Gln21-Asp728) hFc(Glu99-Ala330), Protein function: Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin....
| Schlagworte: | Integrin alpha 2 beta 1, ITGA2 and ITGB1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 121.8 kD |
ab 105,00 €
Human STAB1 Protein, hFc Tag
Artikelnummer: DIM-PME100718.10
Recombinant human STAB1 protein with C-terminal human Fc tag. STAB1(Asp638-Leu1024) hFc(Glu99-Ala330), Protein function: Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When...
| Schlagworte: | Stabilin-1, FEEL-1, MS-1 antigen |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 66.7 kD |
ab 105,00 €
Human STAB1 Protein, His Tag
Artikelnummer: DIM-PME100719.10
Recombinant human STAB1 protein with C-terminal 6×His tag. STAB1(Asp638-Leu1024) 6×His tag, Protein function: Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in...
| Schlagworte: | Stabilin-1, FEEL-1, MS-1 antigen |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 41.4 kD |
ab 105,00 €
Human NPC1L1 Protein, His Tag
Artikelnummer: DIM-PME100720.10
Recombinant human NPC1L1 protein with C-terminal 6×His tag. NPC1L1(Glu22-Ser284) 6×His tag, Protein function: Plays a major role in cholesterol homeostasis. Is critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte. Is the direct molecular target of ezetimibe, a drug that...
| Schlagworte: | NPC1-like intracellular cholesterol transporter 1, Niemann-Pick C1-like protein 1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 28.8 kD |
ab 114,00 €
Human ADAM28 Protein, His Tag
Artikelnummer: DIM-PME100721.10
Recombinant human ADAM28 protein with C-terminal 6×His tag. ADAM28(Ile19-His664) 6×His tag, Protein function: May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be...
| Schlagworte: | eMDC II, MDC-L |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 73.7 kD |
ab 105,00 €
Human GCGR Protein, hFc Tag
Artikelnummer: DIM-PME100722.10
Recombinant human GCGR protein with C-terminal human Fc tag. GCGR(Ala26-Lys136) hFc(Glu99-Ala330), Protein function: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting...
| Schlagworte: | GL-R |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.2 kD |
ab 105,00 €
Human TEM1 Protein, His Tag
Artikelnummer: DIM-PME100723.10
Recombinant human TEM1 protein with C-terminal 6×His tag. TEM1(Gln18-Arg685) 6×His tag, Protein function: May play a role in tumor angiogenesis. [The UniProt Consortium]
| Schlagworte: | Endosialin, CD248, CD164L1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 72.1 kD |
ab 114,00 €