Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human CD205 Protein, His Tag
Artikelnummer: DIM-PME100643.10
Recombinant human CD205 protein with C-terminal 6×His tag. CD205(Ser28-Asp1666) 6×His tag, Protein function: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B- lymphocytes. [The UniProt Consortium]
| Schlagworte: | LY75, CLEC13B, DEC-205, GP200-MR6, LY-75 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 189.6 kD |
ab 114,00 €
Human CD23 Protein, His Tag
Artikelnummer: DIM-PME100644.10
Recombinant human CD23 protein with N-terminal 6×His tag. 6×His tag CD23(Asp48-Ser321), Protein function: Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). [The UniProt...
| Schlagworte: | BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 31.8 kD |
ab 105,00 €
Human SIGLEC7 Protein, His Tag
Artikelnummer: DIM-PME100645.10
Recombinant human SIGLEC7 protein with C-terminal 6×His tag. SIGLEC7(Gln19-Leu353) 6×His tag, Protein function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl...
| Schlagworte: | AIRM-1, AIRM1, CD328, CDw328, D-siglec, p75, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 38.6 kD |
ab 105,00 €
Human NOTCH3 Protein, hFc Tag
Artikelnummer: DIM-PME100646.10
Recombinant human NOTCH3 protein with C-terminal human Fc tag. NOTCH3(Ala40-Glu467) hFc(Glu99-Ala330), Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543). Upon ligand activation through the released notch...
| Schlagworte: | CADASIL, CADASIL1, CASIL, IMF2, LMNS |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 70.9 kD |
ab 120,00 €
SARS-CoV-2 (Delta) S protein RBD, His Tag
Artikelnummer: DIM-PME100647.10
Recombinant SARS-CoV-2 RBD(L452R,T478K) protein with C-terminal 6×His tag. RBD(L452R,T478K)(Ser19-Glu351) 6×His tag, Protein function: Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome...
| Schlagworte: | SARS-CoV-2 B.1.617.2 (Delta) Spike RBD Protein |
| Exprimiert in: | Human cells |
| Ursprungsart: | SARS-CoV-2 |
| CAS | 12 |
| MW: | 26.0 kD |
ab 105,00 €
Human NEFL (89-400) Protein, His Tag
Artikelnummer: DIM-PME100648.10
Recombinant human NEFL(89-400) protein with N-terminal 6×His tag. 6×His tag NEFL(Gln89-Leu400), Protein function: Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal...
| Schlagworte: | CMT1F, CMT2E, CMTDIG, NF-L, NF68, NFL, PPP1R110 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 36.9 kD |
ab 120,00 €
Human KRAS Protein, His Tag
Artikelnummer: DIM-PME100649.10
Recombinant human KRAS protein with C-terminal 6×His tag. KRAS(Thr2-Cys185) 6×His tag, Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621). Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting...
| Schlagworte: | C-K-RAS, c-Ki-ras2, CFC2, K-Ras, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RALD, RASK2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 21.8 kD |
ab 120,00 €
Human FZD10 Protein, hFc Tag
Artikelnummer: DIM-PME100650.10
Recombinant Human FZD10 with C-terminal human Fc tag. FZD10(Ile21-Gly161) hFc(Glu99-Ala330), Protein function: Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3...
| Schlagworte: | CD350, FZ-10, Fz10, FzE7, hFz10 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 42.2 kD |
ab 114,00 €
Human IL22 Protein, hFc Tag
Artikelnummer: DIM-PME100651.10
Recombinant Human IL22 with C-terminal human Fc tag. IL22(Ala34-Ile179) hFc(Glu99-Ala330), Protein function: Cytokine that contributes to the inflammatory response in vivo. [The UniProt Consortium]
| Schlagworte: | IL-22, IL-TIF, ZCYTO18 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 33.9 kD |
ab 114,00 €
Human TNFRSF25 Protein, hFc Tag
Artikelnummer: DIM-PME100652.10
Recombinant Human TNFRSF25 with C-terminal human Fc tag. TNFRSF25(Gln25-Gln199) hFc(Glu99-Ala330), Protein function: Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. [The UniProt...
| Schlagworte: | APO-3, DDR3, DR3, GEF720, LARD, PLEKHG5, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 45.0 kD |
ab 120,00 €
Human GRP Protein, hFc Tag
Artikelnummer: DIM-PME100653.10
Recombinant Human GRP with C-terminal human Fc tag. GRP(Val24-Met50) hFc(Glu99-Ala330), Protein function: Stimulates the release of gastrin and other gastrointestinal hormones. Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching...
| Schlagworte: | BN, GRP-10, preproGRP, proGRP |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 29.0 kD |
ab 105,00 €
Human NEFL (9-88) Protein, hFc Tag
Artikelnummer: DIM-PME100654.10
Recombinant Human NEFL(9-88) with C-terminal human Fc tag. NEFL(Tyr9-Thr88) hFc(Glu99-Ala330), Protein function: Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal...
| Schlagworte: | CMT1F, CMT2E, CMTDIG, NF-L, NF68, NFL, PPP1R110 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 34.9 kD |
ab 124,00 €