Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human EPHB2 Protein, His Tag
Artikelnummer: DIM-PME100631.10
Recombinant human EPHB2 protein with C-terminal 6×His tag. EPHB2(Val19-Leu543) 6×His tag, Protein function: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling...
| Schlagworte: | BDPLT22, CAPB, DRT, EK5, EPHT3, ERK, Hek5, PCBC, Tyro5 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 58.9 kD |
ab 105,00 €
Human GP1BB Protein, hFc Tag
Artikelnummer: DIM-PME100632.10
Recombinant Human GP1BB with C-terminal human Fc tag. GP1BB(Pro27-Cys147) hFc(Glu99-Ala330), Protein function: Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium. [The UniProt Consortium]
| Schlagworte: | BDPLT1, BS, CD42C, GPIBB, GPIbbeta |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.0 kD |
ab 120,00 €
Human TREM2 Protein, hFc Tag
Artikelnummer: DIM-PME100633.10
Recombinant Human TREM2 with C-terminal human Fc tag. TREM2(His19-Ser174) hFc(Glu99-Ala330), Protein function: Forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of...
| Schlagworte: | PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 43.6 kD |
ab 124,00 €
Human MMP9(107-707) Protein, His Tag
Artikelnummer: DIM-PME100634.10
Recombinant human MMP9 protein with C-terminal 6×His tag. MMP9(Phe107-Asp707) 6×His tag, Protein function: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-, -Leu bond. Cleaves type IV and...
| Schlagworte: | CLG4B, GELB, MANDP2, MMP-9 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 67.4 kD |
ab 176,00 €
Human APCDD1 Protein, His Tag
Artikelnummer: DIM-PME100635.10
Recombinant human APCDD1 protein with C-terminal 6×His tag. APCDD1(Leu27-His492) 6×His tag, Protein function: Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta- catenin. May act via its interaction with Wnt and LRP proteins. May play a...
| Schlagworte: | B7323, DRAPC1, FP7019, HHS, HTS, HYPT1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 54.1 kD |
ab 105,00 €
Human GP6 Protein, hFc Tag
Artikelnummer: DIM-PME100636.10
Recombinant Human GP6 with C-terminal human Fc tag. GP6(Gln21-Lys267) hFc(Glu99-Ala330), Protein function: Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may...
| Schlagworte: | BDPLT11, GPIV, GPVI |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 53.1 kD |
ab 105,00 €
Human TSLP Protein, hFc Tag
Artikelnummer: DIM-PME100637.10
Recombinant Human TSLP with C-terminal human Fc tag. TSLP(Tyr29-Gln159) hFc(Glu99-Ala330), Protein function: [Isoform 1]: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by...
| Schlagworte: | TSLP |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 41.1 kD |
ab 176,00 €
Human GHR Protein, hFc Tag
Artikelnummer: DIM-PME100638.10
Recombinant Human GHR with C-terminal human Fc tag. GHR(Ala27-Tyr264) hFc(Glu99-Ala330), Protein function: Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. [The UniProt Consortium]
| Schlagworte: | GHBP, GHIP |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 53.8 kD |
ab 105,00 €
Human IL11 Protein, hFc Tag
Artikelnummer: DIM-PME100639.10
Recombinant Human IL11 with C-terminal human Fc tag. IL11(Pro22-Leu199) hFc(Glu99-Ala330), Protein function: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also...
| Schlagworte: | AGIF, IL-11 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 45.3 kD |
ab 120,00 €
Human BST1 Protein, hFc Tag
Artikelnummer: DIM-PME100640.10
Recombinant Human BST1 with C-terminal human Fc tag. BST1(Gly29-Lys292) hFc(Glu99-Ala330), Protein function: Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in...
| Schlagworte: | CD157 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 56.1 kD |
ab 105,00 €
Human CD74 (73-232) Protein, hFc Tag
Artikelnummer: DIM-PME100641.10
Recombinant Human CD74(73-232) Protein with N-terminal human Fc tag. hFc(Glu99-Ala330) CD74(Gln73-Met232), Protein function: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the...
| Schlagworte: | DHLAG, HLADG, Ia-GAMMA, II, p33 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 44.4 kD |
ab 105,00 €
Human CD74 (73-296) Protein, hFc Tag
Artikelnummer: DIM-PME100642.10
Recombinant Human CD74(73-296) Protein with N-terminal human Fc tag. hFc(Glu99-Ala330) CD74(Gln73-Met296), Protein function: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the...
| Schlagworte: | DHLAG, HLADG, Ia-GAMMA, II, p33 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 51.5 kD |
ab 105,00 €