Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human FZD4 Protein, hFc Tag
Artikelnummer: DIM-PME100618.10
Recombinant Human FZD4 with C-terminal human Fc tag. FZD4(Phe37-Glu180) hFc(Glu99-Ala330), Protein function: Receptor for Wnt proteins (PubMed:30135577). Most frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of...
| Schlagworte: | CD344, EVR1, FEVR, Fz-4, Fz4, FZD4S, FzE4, GPCR, hFz4 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 42.4 kD |
ab 105,00 €
Human GAS6 Protein, His Tag
Artikelnummer: DIM-PME100619.10
Recombinant human GAS6 protein with C-terminal 6×His tag. GAS6(Ala31-Ala678) 6×His tag, Protein function: Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes...
| Schlagworte: | AXLLG, AXSF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 72.7 kD |
ab 140,00 €
Human GFRA3 Protein, His Tag
Artikelnummer: DIM-PME100620.10
Recombinant human GFRA3 protein with C-terminal 6×His tag. GFRA3(Asp32-Asn374) 6×His tag, Protein function: Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase. [The UniProt Consortium]
| Schlagworte: | GDNFR3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.1 kD |
ab 105,00 €
Human GFRAL Protein, His Tag
Artikelnummer: DIM-PME100621.10
Recombinant human GFRAL protein with C-terminal 6×His tag. GFRAL(Ser19-Glu351) 6×His tag, Protein function: Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098,...
| Schlagworte: | bA360D14.1, C6orf144, GRAL, UNQ9356 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 38.6 kD |
ab 120,00 €
Human ADGRE1 Protein, His Tag
Artikelnummer: DIM-PME100622.10
Recombinant human ADGRE1 protein with C-terminal 6×His tag. ADGRE1(His21-Asp599) 6×His tag, Protein function: Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. [The UniProt...
| Schlagworte: | EMR1, TM7LN3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 63.9 kD |
ab 105,00 €
Human CHI3L1 Protein, His Tag
Artikelnummer: DIM-PME100623.10
Recombinant human CHI3L1 protein with C-terminal 6×His tag. CHI3L1(Tyr22-Thr383) 6×His tag, Protein function: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their...
| Schlagworte: | ASRT7, CGP-39, GP-39, GP39, HC-gp39, HCGP-3P, hCGP-39, YK-40, YKL-40, YKL40, YYL-40 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 41.3 kD |
ab 105,00 €
Human EPHA4 Protein, His Tag
Artikelnummer: DIM-PME100624.10
Recombinant human EPHA4 protein with C-terminal 6×His tag. EPHA4(Val20-Thr547) 6×His tag, Protein function: Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway...
| Schlagworte: | EK8, HEK8, SEK, TYRO1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 59.2 kD |
ab 105,00 €
Human FCRL5 Protein, His Tag
Artikelnummer: DIM-PME100625.10
Recombinant human FCRL5 protein with C-terminal 6×His tag. FCRL5(Gln16-Thr850) 6×His tag, Protein function: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. [The UniProt...
| Schlagworte: | BXMAS1, CD307, CD307e, FCRH5, IRTA2, PRO820 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 92.1 kD |
ab 105,00 €
Human IL17C Protein, hFc Tag
Artikelnummer: DIM-PME100627.10
Recombinant Human IL17C with C-terminal human Fc tag. IL17C(His19-Val197) hFc(Glu99-Ala330), Protein function: Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and...
| Schlagworte: | CX2, IL-17C |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 45.9 kD |
ab 120,00 €
Human GDF15 Protein, hFc Tag
Artikelnummer: DIM-PME100628.10
Recombinant Human GDF15 Protein with N-terminal human Fc tag. hFc(Glu99-Ala330) GDF15(Ala197-Ile308), Protein function: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844,...
| Schlagworte: | GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 38.4 kD |
ab 120,00 €
Human UCHL1 Protein, hFc Tag
Artikelnummer: DIM-PME100629.10
Recombinant Human UCHL1 Protein with N-terminal human Fc tag. hFc(Glu99-Ala330) UCHL1(Met1-Cys220), Protein function: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (Probable). This enzyme is a thiol protease that recognizes and hydrolyzes a peptide...
| Schlagworte: | HEL-117, HEL-S-53, NDGOA, PARK5, PGP 9.5, PGP9.5, PGP95, SPG79, Uch-L1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 50.7 kD |
ab 120,00 €
Human ROR1 (312-391) Protein, hFc Tag
Artikelnummer: DIM-PME100630.10
Recombinant Human ROR1(312-391) Protein with N-terminal human Fc tag. hFc(Glu99-Ala330) ROR1(Lys312-Cys391), Protein function: Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway...
| Schlagworte: | ROR1, NTRKR1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 35.2 kD |
ab 105,00 €