Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human PGF Protein, hFc Tag
Artikelnummer: DIM-PME100579.10
Recombinant Human PGF with C-terminal human Fc tag. PGF(Leu19-Arg170) hFc(Glu99-Ala330), Protein function: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and...
| Schlagworte: | D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 43.5 kD |
ab 124,00 €
Human APP Protein, His Tag
Artikelnummer: DIM-PME100580.10
Recombinant Human APP Protein with C-terminal 6×His tag. APP(Leu18-Val669) 6×His Tag, Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring...
| Schlagworte: | AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, preA4 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 74.6 kD |
ab 105,00 €
Human CD45 Protein, His Tag
Artikelnummer: DIM-PME100581.10
Recombinant Human CD45 with C-terminal 6×His tag. CD45(Gln26-Lys577) 6×His tag, Protein function: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity,...
| Schlagworte: | B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 61.6 kD |
ab 133,00 €
Human CD26 Protein, His Tag
Artikelnummer: DIM-PME100582.10
Recombinant Human CD26 with C-terminal 6×His tag. CD26(Asp34-Pro766) 6×His tag, Protein function: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation (PubMed:10951221, PubMed:10900005, PubMed:11772392, PubMed:17287217). Acts as a...
| Schlagworte: | ADABP, ADCP2, CD26, DPPIV, TP103 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 85.7 kD |
ab 105,00 €
Human CFB Protein, hFc Tag
Artikelnummer: DIM-PME100584.10
Recombinant Human CFB with C-terminal human Fc tag. CFB(Thr26-Leu764) hFc(Glu99-Ala330), Protein function: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or...
| Schlagworte: | AHUS4, ARMD14, BF, BFD, CFAB, CFBD, FB, FBI12, GBG, H2-Bf, PBF2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 109.2 kD |
ab 105,00 €
Human IL21R Protein, mFc Tag
Artikelnummer: DIM-PME100586.10
Recombinant Human IL21R with C-terminal mouse Fc tag. IL21R(Cys20-Glu232) mFc(Pro99-Lys330), Protein function: This is a receptor for interleukin-21. [The UniProt Consortium]
| Schlagworte: | CD360, IMD56, NILR |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 50.7 kD |
ab 124,00 €
Human IL21R Protein, His Tag
Artikelnummer: DIM-PME100587.10
Recombinant Human IL21R with C-terminal 6×His tag. IL21R(Cys20-Glu232) 6×His tag, Protein function: This is a receptor for interleukin-21. [The UniProt Consortium]
| Schlagworte: | CD360, IMD56, NILR |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 25.4 kD |
ab 120,00 €
Human c-MPL Protein, hFc Tag
Artikelnummer: DIM-PME100588.10
Recombinant Human c-MPL with C-terminal human Fc tag. c-MPL(Gln26-Ala490) hFc(Glu99-Ala330), Protein function: Receptor for thrombopoietin that acts as a primary regulator of megakaryopoiesis and platelet production. May represent a regulatory molecule specific for TPO-R-dependent immune responses. [The UniProt...
| Schlagworte: | C-MPL, CD110, MPLV, THCYT2, THPOR, TPOR |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 78.5 kD |
ab 120,00 €
Human MDR-1 Protein, hFc Tag
Artikelnummer: DIM-PME100589.10
Recombinant Human MDR-1 with C-terminal human Fc tag. MDR-1(Phe72-Arg113) (Lys213-Thr215) (Thr318-Gln330) (Gly960-Asp973) hFc(Glu99-Ala330), Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the...
| Schlagworte: | ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 34.2 kD |
ab 105,00 €
Human CD26 (29-766) Protein, His Tag
Artikelnummer: DIM-PME100590.10
Recombinant Human CD26 with C-terminal 6×His tag. CD26(Asn29-Pro766) 6×His tag, Protein function: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation (PubMed:10951221, PubMed:10900005, PubMed:11772392, PubMed:17287217). Acts as a...
| Schlagworte: | ADABP, ADCP2, CD26, DPPIV, TP103 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 111.5 kD |
ab 105,00 €
Human ALB Protein, His Tag
Artikelnummer: DIM-PME100591.10
Recombinant Human ALB with C-terminal 6×His tag. ALB(Asp25-Leu609) 6×His tag, Protein function: Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma,...
| Schlagworte: | HSA, PRO0883, PRO0903, PRO1341 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 67.3 kD |
ab 133,00 €
Human FGFR4 Protein, His Tag
Artikelnummer: DIM-PME100592.10
Recombinant Human FGFR4 Protein with C-terminal 6×His tag. FGFR4(Leu22-Asp369) 6×His Tag, Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid...
| Schlagworte: | CD334, JTK2, TKF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 39.3 kD |
ab 105,00 €