Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human NTRK3 Protein, hFc Tag
Artikelnummer: DIM-PME100566.10
Recombinant human NTRK3 protein with C-terminal human Fc tag. NTRK3(Cys32-Thr429) hFc(Glu99-Ala330), Protein function: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling...
| Schlagworte: | gp145(trkC), GP145-TrkC, TRKC |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 70.9 kD |
ab 105,00 €
Human BCL2L1 Protein, hFc Tag
Artikelnummer: DIM-PME100567.10
Recombinant human BCL2L1 protein with C-terminal human Fc tag. BCL2L1(Met1-Arg212) hFc(Glu99-Ala330), Protein function: Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release...
| Schlagworte: | Bcl-X, BCL-XL/S, BCL2L, BCLX, PPP1R52 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 49.9 kD |
ab 105,00 €
Human M-CSF Protein, mFc Tag
Artikelnummer: DIM-PME100568.10
Recombinant Human M-CSF with C-terminal mouse Fc tag. M-CSF(Glu33-Arg255) mFc(Pro99-Lys330), Protein function: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes....
| Schlagworte: | CSF-1, MCSF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 51.2 kD |
ab 140,00 €
Human M-CSF Protein, His Tag
Artikelnummer: DIM-PME100569.10
Recombinant Human M-CSF with C-terminal 6×His tag. M-CSF(Glu33-Arg255) 6×His tag, Protein function: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes...
| Schlagworte: | CSF-1, MCSF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 26 kD |
ab 124,00 €
SARS-CoV-2 (Kappa) nCoV S Protein RBD Protein, hFc Tag
Artikelnummer: DIM-PME100570.10
Recombinant SARS-CoV-2 RBD (L452RandE484Q) protein with C-terminal human Fc tag. S protein RBD(L452Rand E484Q)(Arg319-Phe541) hFc(Glu99-Ala330), Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2...
| Schlagworte: | SARS-CoV-2 B.1.617/B.1.617.1/B.1.617.3 (Kappa) Spike RBD Protein |
| Exprimiert in: | Human cells |
| Ursprungsart: | SARS-CoV-2 |
| CAS | 12 |
| MW: | 51.2 kD |
ab 105,00 €
Human NTRK1 Protein, hFc Tag
Artikelnummer: DIM-PME100571.10
Recombinant Human NTRK1 Protein with C-terminal human Fc tag. NTRK1(Ala33-Phe410) hFc(Glu99-Ala330), Protein function: Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic...
| Schlagworte: | MTC, p140-TrkA, TRK, Trk-A, TRK1, TRKA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 67.4 kD |
ab 105,00 €
Human SLC7A11 Protein, hFc Tag
Artikelnummer: DIM-PME100572.10
Recombinant Human SLC7A11 Protein with C-terminal human Fc tag. SLC7A11(Lys67-Gly74) (Leu151-Cys158) (Lys215-Thr233) (Thr219-Leu317) (Asp386-Ser387) (Ser445-Pro447) hFc(Glu99-Ala330), Protein function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine...
| Schlagworte: | CCBR1, xCT |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 33.4 kD |
ab 105,00 €
Human IL2 Protein, mFc Tag
Artikelnummer: DIM-PME100574.10
Recombinant Human IL2 with C-terminal mouse Fc tag. IL2(Ala21-Thr153) mFc(Pro99-Lys330), Protein function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells,...
| Schlagworte: | IL-2, lymphokine, TCGF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 41.5 kD |
ab 124,00 €
Human CD112 Protein, mFc Tag
Artikelnummer: DIM-PME100575.10
Recombinant Human CD112 with C-terminal mouse Fc tag. CD112(Gln32-Gly360) mFc(Pro99-Lys330), Protein function: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine...
| Schlagworte: | NECTIN2, HVEB, PRR2, PVRL2, PVRR2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 61.4 kD |
ab 140,00 €
Human CD112 Protein, His Tag
Artikelnummer: DIM-PME100576.10
Recombinant Human CD112 with C-terminal 6×His tag. CD112(Gln32-Gly360) 6×His tag, Protein function: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production,...
| Schlagworte: | NECTIN2, HVEB, PRR2, PVRL2, PVRR2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 36.1 kD |
ab 124,00 €
Human TLR3 Protein, His Tag
Artikelnummer: DIM-PME100577.10
Recombinant human TLR3 protein with C-terminal 6×His tag. TLR3(Ser24-Leu704) 6×His tag, Protein function: Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a...
| Schlagworte: | TLR3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 78.2 kD |
ab 114,00 €
Human IL11RA Protein, hFc Tag
Artikelnummer: DIM-PME100578.10
Recombinant Human IL11RA with C-terminal human Fc tag. IL11RA(Ser24-Ala370) hFc(Glu99-Ala330), Protein function: Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the...
| Schlagworte: | IL-11 R alpha, IL-11 RA, IL11RA, Interleukin-11 receptor subunit alpha, IL-11 receptor subunit alpha, IL-11R subunit... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 44.3 kD |
ab 120,00 €