Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human IL4RA Protein, His Tag
Artikelnummer: DIM-PME100552.10
Recombinant human IL4RA protein with C-terminal 6×His tag. IL4RA(Met26-His232) 6×His tag, Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE...
| Schlagworte: | CD124, IL-4RA, IL4RA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 24.6 kD |
ab 114,00 €
Human CD112 Protein, hFc Tag
Artikelnummer: DIM-PME100553.10
Recombinant Human CD112 Protein with C-terminal human Fc tag. CD112(Gln32-Gly360) hFc(Glu99-Ala330), Protein function: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and...
| Schlagworte: | NECTIN2, HVEB, PRR2, PVRL2, PVRR2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 61.4 kD |
ab 124,00 €
Human JAM-A Protein, hFc Tag
Artikelnummer: DIM-PME100554.10
Recombinant Human JAM-A Protein with C-terminal human Fc tag. JAM-A(Ser28-Val238) hFc(Glu99-Ala330), Protein function: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may...
| Schlagworte: | CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 49.1 kD |
ab 124,00 €
Human IL21 Protein, mFc Tag
Artikelnummer: DIM-PME100555.10
Recombinant Human IL21 with C-terminal mouse Fc tag. IL21(Gln30-Ser162) mFc(Pro99-Lys330), Protein function: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance...
| Schlagworte: | IL21, Za11, Interleukin-21 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 41.6 kD |
ab 120,00 €
Human IL21 Protein, His Tag
Artikelnummer: DIM-PME100556.10
Recombinant Human IL21 with C-terminal 6×His tag. IL21(Gln30-Ser162) 6×His tag, Protein function: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T...
| Schlagworte: | IL21, Za11, Interleukin-21 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 16.3 kD |
ab 114,00 €
Human IL2 Protein, His Tag
Artikelnummer: DIM-PME100557.10
Recombinant Human IL2 with C-terminal 6×His tag. IL2(Ala21-Thr153) 6×His tag, Protein function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes,...
| Schlagworte: | IL-2, lymphokine, TCGF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 16.2 kD |
ab 140,00 €
Human IL18 Protein, mFc Tag
Artikelnummer: DIM-PME100558.10
Recombinant Human IL18 with C-terminal mouse Fc tag. IL18(Tyr37-Asp193) mFc(Pro99-Lys330), Protein function: A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary...
| Schlagworte: | IGIF, IL-1g, IL-18, IL1F4 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 44.3 kD |
ab 176,00 €
Mouse GPRC5D Protein, hFc Tag
Artikelnummer: DIM-PME100560.10
Recombinant mouse GPRC5D protein with C-terminal human Fc tag. Mouse GPRC5D(Met1-Pro21) hFc(Glu99-Ala330)
| Schlagworte: | GPRC5D |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| CAS | 12 |
| MW: | 28.7 kD |
ab 105,00 €
Cynomolgus GPRC5D (1-21) Protein, hFc Tag
Artikelnummer: DIM-PME100561.10
Recombinant Cynomolgus GPRC5D protein with C-terminal human Fc tag. cGPRC5D(Met1-Pro21) hFc(Glu99-Ala330)
| Schlagworte: | GPRC5D |
| Exprimiert in: | Human cells |
| Ursprungsart: | Cynomolgus |
| CAS | 12 |
| MW: | 28.5 kD |
ab 105,00 €
Human PCSK9 Protein, hFc Tag
Artikelnummer: DIM-PME100562.10
Recombinant Human PCSK9 Protein with C-terminal human Fc tag. PCSK9(Gln31-Gln692) hFc(Glu99-Ala330), Protein function: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor...
| Schlagworte: | FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 97.2 kD |
ab 105,00 €
Human SCF Protein, hFc Tag
Artikelnummer: DIM-PME100563.10
Recombinant human SCF protein with C-terminal human Fc tag. SCF(Glu26-His214) hFc(Glu99-Ala330), Protein function: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell...
| Schlagworte: | DCUA, DFNA69, FPH2, FPHH, Kitl, KL-1, MGF, SCF, SF, SHEP7, SLF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 47.2 kD |
ab 114,00 €
Human GM-CSF Protein, hFc Tag
Artikelnummer: DIM-PME100564.10
Recombinant Human GM-CSF Protein with C-terminal human Fc tag. GM-CSF(Ala18-Glu144) hFc(Glu99-Ala330), Protein function: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. [The UniProt...
| Schlagworte: | CSF, GMCSF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 40.6 kD |
ab 176,00 €