Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-5T4 (H8 biosimilar) mAb
Artikelnummer: DIM-BME100157.100
Protein function: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. [The UniProt Consortium]
| Schlagworte: | Anti-M6P1, Anti-WAIF1, Anti-TPBG, Anti-5T4 (H8 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-5T4 (GEN-1044 biosimilar) mAb
Artikelnummer: DIM-BME100158.100
Protein function: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. [The UniProt Consortium]
| Schlagworte: | Anti-M6P1, Anti-WAIF1, Anti-TPBG, Anti-5T4 (GEN-1044 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-TM4SF1 (AGX101 biosimilar) mAb
Artikelnummer: DIM-BME100159.100
| Schlagworte: | Anti-M3S1, Anti-TAAL6, Anti-TM4SF1 (AGX101 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD20 (obinutuzumab biosimilar) mAb
Artikelnummer: DIM-BME100160.100
Protein function: B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC) channel component...
| Schlagworte: | Anti-B1, Anti-Bp35, Anti-MS4A1, Anti-CVID5, Anti-LEU-16, Anti-MS4A2, Anti-S7, Anti-CD20 (obinutuzumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-KLRG1(ulviprubart biosimilar) mAb
Artikelnummer: DIM-BME100162.100
Protein function: Plays an inhibitory role on natural killer (NK) cells and T- cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E- cadherin/CDH1, N-cadherin/CDH2 and...
| Schlagworte: | Anti-2F1, Anti-CLEC15A, Anti-MAFA, Anti-MAFA-2F1, Anti-MAFA-L, Anti-MAFA-LIKE, Anti-KLRG1(ulviprubart biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-FOLR1(farletuzumab biosimilar) mAb
Artikelnummer: DIM-BME100163.100
Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation...
| Schlagworte: | Anti-FBP, Anti-FOLR, Anti-FRalpha, Anti-NCFTD, Anti-FOLR1(farletuzumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL23A(guselkumab biosimilar) mAb
Artikelnummer: DIM-BME100164.100
Protein function: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R,...
| Schlagworte: | Anti-SGRF, Anti-IL23A(guselkumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-Mesothelin VHH-human IgG1 Fc
Artikelnummer: DIM-BME100165.100
Protein function: Membrane-anchored forms may play a role in cellular adhesion. [The UniProt Consortium]
| Schlagworte: | Anti-MSLN, Anti-MPF, Anti-Mesothelin VHH-human IgG1 Fc |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CGRPR(Erenumab biosimilar) mAb
Artikelnummer: DIM-BME100166.100
Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2 (PubMed:22102369, PubMed:30115739). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase...
| Schlagworte: | Anti-CALCRL, Anti-CGRPR(Erenumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-ALPP(TCRCure A06 Biosimilar) mAb
Artikelnummer: DIM-BME100167.100
| Schlagworte: | Anti-PLAP-1, Anti-PLAP, Anti-ALPP(TCRCure A06 Biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD70 (Chongqing Precision biosimilar) mAb
Artikelnummer: DIM-BME100168.100
Protein function: Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses. Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells....
| Schlagworte: | Anti-CD27L, Anti-CD27LG, Anti-TNFSF7, Anti-CD70 (Chongqing Precision biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-ROR2(ozuriftamab biosimilar) mAb
Artikelnummer: DIM-BME100169.100
Protein function: Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to...
| Schlagworte: | Anti-NTRKR2, Anti-ROR2(ozuriftamab biosimilar) mAb |
| Wirt: | Chimeric Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €