Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human IL5 Protein, hFc Tag
Artikelnummer: DIM-PME100537.10
Recombinant Human IL5 protein with C-terminal human Fc tag. IL5(Ile20-Ser134) hFc(Glu99-Ala330), Protein function: Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. [The UniProt Consortium]
| Schlagworte: | IL-5, TRF, Interleukin-5, EDF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.3 kD |
ab 140,00 €
SARS-CoV-2 (Beta) S protein RBD, hFc Tag
Artikelnummer: DIM-PME100539.10
Recombinant SARS-CoV-2 S protein RBD(K417N, E484K,N501Y) protein with C-terminal human Fc tag. S protein RBD(K417N, E484K,N501Y)(Arg319-Phe541) hFc(Glu99-Ala330), Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major...
| Schlagworte: | SARS-CoV-2 B.1.351 (Beta) Spike RBD Protein |
| Exprimiert in: | Human cells |
| Ursprungsart: | SARS-CoV-2 |
| MW: | 51.3 kD |
ab 114,00 €
Human SLAMF3 Protein, His Tag
Artikelnummer: DIM-PME100541.10
Recombinant human SLAMF3 protein with C-terminal 6×His tag. SLAMF3(Lys48-Lys454) 6×His tag, Protein function: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation...
| Schlagworte: | CD229, hly9, mLY9, SLAMF3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 45.6 kD |
ab 114,00 €
Human TMEM173 Protein, hFc Tag
Artikelnummer: DIM-PME100542.10
Recombinant human TMEM173 protein with N-terminal Human Fc tag. hFc(Glu99-Ala330) TMEM173 (Leu139-Ser379), Protein function: Facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon (IFN-alpha and IFN-beta)...
| Schlagworte: | ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING, STING-beta, TMEM173 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 53.2 kD |
ab 120,00 €
SARS-CoV-2 (Alpha) S protein RBD , hFc Tag
Artikelnummer: DIM-PME100543.10
Recombinant SARS-CoV-2 S protein RBD(N501Y) protein with C-terminal human Fc tag. S protein RBD(N501Y)(Arg319-Phe541) hFc(Glu99-Ala330), Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2...
| Schlagworte: | SARS-CoV-2 B.1.1.7 (Alpha) Spike RBD Protein |
| Exprimiert in: | Human cells |
| Ursprungsart: | SARS-CoV-2 |
| MW: | 51.3 kD |
ab 114,00 €
Human YAP1 Protein, His Tag
Artikelnummer: DIM-PME100544.10
Recombinant human YAP1 protein with C-terminal 6×His tag. YAP1(Met1-Leu504) 6×His tag, Protein function: Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and...
| Schlagworte: | COB1, YAP, YAP2, YAP65, YKI |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 55.3 kD |
ab 105,00 €
Human PSMA Protein, mFc Tag
Artikelnummer: DIM-PME100546.10
Recombinant human PSMA protein with N-terminal mouse Fc tag. mFc(Pro99-Lys330) PSMA(Lys44-Ala750), Protein function: Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of...
| Schlagworte: | FGCP, FOLH, GCP2, GCPII, mGCP, NAALAD1, NAALAdase, PSM, PSMA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 105.8 kD |
ab 120,00 €
Human MUC1 Protein, hFc Tag
Artikelnummer: DIM-PME100547.10
Recombinant Human MUC1 Protein with C-terminal human Fc tag. MUC1(Leu1036-Val1156) hFc(Glu99-Ala330), Protein function: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack....
| Schlagworte: | ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.7 kD |
ab 105,00 €
Human IL15RA Protein, hFc Tag
Artikelnummer: DIM-PME100548.10
Recombinant Human IL15RA Protein with C-terminal human Fc tag. IL15RA(Ile31-Thr205) hFc(Glu99-Ala330), Protein function: High-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In...
| Schlagworte: | CD215 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 44.5 kD |
ab 105,00 €
Human AMHR2 Protein, hFc Tag
Artikelnummer: DIM-PME100549.10
Recombinant Human AMHR2 Protein with C-terminal human Fc tag. AMHR2 (Pro18-Leu149) hFc(Glu99-Ala330), Protein function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which...
| Schlagworte: | AMHR, MISR2, MISRII, MRII |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 40.3 kD |
ab 124,00 €
Human M-CSF Protein, hFc Tag
Artikelnummer: DIM-PME100550.10
Recombinant Human M-CSF Protein with C-terminal human Fc tag. M-CSF(Glu33-Arg255) hFc(Glu99-Ala330), Protein function: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and...
| Schlagworte: | CSF-1, MCSF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 51.3 kD |
ab 140,00 €
Human IL4RA Protein, mFc Tag
Artikelnummer: DIM-PME100551.10
Recombinant Human IL4RA with C-terminal mouse Fc tag. IL4RA(Met26-His232) mFc(Pro99-Lys330), Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating...
| Schlagworte: | CD124, IL-4RA, IL4RA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 49.8 kD |
ab 124,00 €