Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human BTLA Protein, His Tag
Artikelnummer: DIM-PME100524.10
Recombinant human BTLA protein with C-terminal 6×His tag. Human BTLA(Lys31-Ser150) 6×His tag, Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact...
| Schlagworte: | BTLA, CD272 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 14.6 kD |
ab 140,00 €
Mouse BTLA Protein, mFc Tag
Artikelnummer: DIM-PME100525.10
Recombinant mouse BTLA protein with C-terminal mFc tag. Mouse BTLA(Glu30-Pro176) mFc(Pro99-Lys330), Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006). May interact in cis (on the same cell) or...
| Schlagworte: | BTLA, D272 |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | 42.7 kD |
ab 114,00 €
Mouse BTLA Protein, His Tag
Artikelnummer: DIM-PME100526.10
Recombinant mouse BTLA protein with C-terminal 6×His tag. Mouse BTLA(Glu30-Pro176) 6×His tag, Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006). May interact in cis (on the same cell) or in...
| Schlagworte: | BTLA, D272 |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | 17.4 kD |
ab 114,00 €
Human ANGPTL3 Protein, His Tag
Artikelnummer: DIM-PME100527.10
Recombinant human ANGPTL3 protein with C-terminal 6×His tag. ANGPTL3(Ser17-Arg221) 6×His tag, Protein function: Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism (PubMed:11788823, PubMed:12909640, PubMed:23661675, PubMed:25495645). Proposed to play a role in the trafficking...
| Schlagworte: | ANG-5, ANGPT5, ANL3, FHBL2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 24.8 kD |
ab 105,00 €
Mouse FAP Protein, N-mFc Tag
Artikelnummer: DIM-PME100528.10
Recombinant mouse FAP protein with N-mFc tag. mFc(Pro99-Lys330) Mouse FAP(Leu26-Asp761), Protein function: Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and...
| Schlagworte: | SIMP, APCE |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | 111.5 kD |
ab 120,00 €
Mouse FAP Protein, C-mFc Tag
Artikelnummer: DIM-PME100529.10
Recombinant mouse FAP protein with C-terminal mFc tag. Mouse FAP(Leu26-Asp761) mFc(Pro99-Lys330), Protein function: Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing,...
| Schlagworte: | SIMP, APCE |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | 111.4 kD |
ab 120,00 €
Human CD38 Protein, hFc Tag
Artikelnummer: DIM-PME100530.10
Recombinant human CD38 protein with C-terminal human Fc tag. CD38(Val43-Ile300) hFc(Glu99-Ala330), Protein function: Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase...
| Schlagworte: | CD38, T10, cADPr hydrolase 1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 56.0 kD |
ab 124,00 €
Human SIRPa Protein, mFc Tag
Artikelnummer: DIM-PME100531.10
Recombinant Human SIRPa with C-terminal mouse Fc tag. SIRPa(Glu31-Tyr373) mFc(Pro99-Lys330), Protein function: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion...
| Schlagworte: | SHPS1, SIRPA, CD172A, BIT, MFR, MYD1, P84, PTPNS |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 63.8 kD |
ab 114,00 €
Human AXL Protein, hFc Tag
Artikelnummer: DIM-PME100532.10
Recombinant Human AXL with C-terminal human Fc tag. AXL(Ala26-Pro449) hFc(Glu99-Ala330), Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival,...
| Schlagworte: | AXL, UFO |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 71.9 kD |
ab 120,00 €
Human SFRP2 Protein, His Tag
Artikelnummer: DIM-PME100534.10
Recombinant human SFRP2 protein with C-terminal 6×His tag. SFRP2(Leu25-Cys295) 6×His tag, Protein function: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types....
| Schlagworte: | FRP-2, SARP1, SDF-5 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 31.9 kD |
ab 120,00 €
Human IL6R Protein, hFc Tag
Artikelnummer: DIM-PME100535.10
Recombinant Human IL6R with C-terminal human Fc tag. IL6R(Leu20-Pro365) hFc(Glu99-Ala330), Protein function: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal (PubMed:28265003). Signal activation necessitate an association with IL6ST. Activation leads to the...
| Schlagworte: | CD126, gp80, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 64.7 kD |
ab 114,00 €
Human IL5RA Protein, hFc Tag
Artikelnummer: DIM-PME100536.10
Recombinant human L5RA protein with C-terminal human Fc tag. IL5RA(Asp21-Pro338) hFc(Glu99-Ala330), Protein function: This is the receptor for interleukin-5. The alpha chain binds to IL5. [The UniProt Consortium]
| Schlagworte: | IL5Ra, CD125, IL-5 R alpha |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 62.3 kD |
ab 120,00 €