Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human CD10 Protein, hFc Tag
Artikelnummer: DIM-PME100509.10
Recombinant Human CD10 protein with N-terminal human Fc. hFc(Glu99-Ala330) CD10(Tyr52-Trp750), Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such...
| Schlagworte: | MME, CALLA, CD10, DKFZp686O16152, MGC126681, MGC126707, NEP, SFE, Neprilysin |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 106.1 kD |
ab 105,00 €
Human B7-H6 Protein, His Tag
Artikelnummer: DIM-PME100510.10
Recombinant Human B7-H6 Protein with C-terminal 6×His tag. B7-H6(Asp25-Ser262) 6×His tag, Protein function: Triggers NCR3-dependent natural killer cell activation. [The UniProt Consortium]
| Schlagworte: | B7-H6, NCR3LG1, B7 Homolog 6 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 27.5 kD |
ab 120,00 €
Human BCMA Protein, His Tag
Artikelnummer: DIM-PME100511.10
Recombinant Human BCMA Protein with C-terminal 6×His tag. BCMA(Met1-Ala54) 6×His tag, Protein function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [The UniProt Consortium]
| Schlagworte: | TNFRSF17, CD269, BCM, BCMA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 6.7 kD |
ab 133,00 €
Human LAG3 Protein, His Tag
Artikelnummer: DIM-PME100512.10
Recombinant Human LAG3 Protein with C-terminal 6×His tag. LAG3(Leu23-Leu450) 6×His tag, Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1...
| Schlagworte: | LAG-3, CD223 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 47.0 kD |
ab 120,00 €
Human LAG3 Protein, hFc Tag
Artikelnummer: DIM-PME100513.10
Recombinant human LAG3 Protein with C-terminal Human Fc tag. LAG3(Leu23-Leu450) hFc(Glu99-Ala330), Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as...
| Schlagworte: | LAG-3, CD223 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 72.3 kD |
ab 114,00 €
Human Galectin 9 Protein, hFc Tag
Artikelnummer: DIM-PME100515.10
Recombinant human Galectin 9 Protein with N-terminal human Fc tag. hFc(Glu99-Ala330) Galectin 9 (Ala2-Thr323), Protein function: Binds galactosides (PubMed:18005988). Has high affinity for the Forssman pentasaccharide (PubMed:18005988). Ligand for HAVCR2/TIM3 (PubMed:16286920). Binding to HAVCR2 induces T-helper...
| Schlagworte: | Galectin-9, LGALS9, Ecalectin, Gal-9 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 61.9 kD |
ab 114,00 €
Human MICB Protein, His Tag
Artikelnummer: DIM-PME100516.10
Recombinant Human MICB Protein with C-terminal 6×His tag. MICB(Ala23-Asp309) 6×His tag, Protein function: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. [The...
| Schlagworte: | MIC-B, PERB11.2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 33.5 kD |
ab 124,00 €
Human CD160 Protein, His Tag
Artikelnummer: DIM-PME100517.10
Recombinant human CD160 protein with C-terminal 6×His tag. CD160(Ile27-Ser159) 6×His tag, Protein function: [CD160 antigen]: Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each...
| Schlagworte: | BY55, NK1, NK28 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 15.6 kD |
ab 140,00 €
Human PDL2 Protein, His Tag
Artikelnummer: DIM-PME100518.10
Recombinant human PDL2 protein with C-terminal 6×His tag. PDL2(Leu20-Pro219) 6×His tag, Protein function: Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression...
| Schlagworte: | B7DC, bA574F11.2, Btdc, CD273, PD-L2, PDCD1L2, PDL2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 23.4 kD |
ab 124,00 €
Human CD117 Protein, His Tag
Artikelnummer: DIM-PME100519.10
Recombinant human CD117 protein with C-terminal 6×His tag. CD117(Gln26-Thr520) 6×His tag, Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance,...
| Schlagworte: | C-Kit, CD117, MASTC, PBT, SCFR, KIT |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 56.5 kD |
ab 124,00 €
Human MASP2 Protein, hFc Tag
Artikelnummer: DIM-PME100520.10
Recombinant human MASP2 protein with N-terminal Human Fc tag. hFc(Glu99-Ala330) MASP2 (Gln298-Ser684), Protein function: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to...
| Schlagworte: | MAP19, MASP-2, MASP1P1, sMAP |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 68.4 kD |
ab 120,00 €
Human BTLA Protein, hFc Tag
Artikelnummer: DIM-PME100523.10
Recombinant human BTLA protein with C-terminal Human Fc tag. Human BTLA(Lys31-Ser150) hFc(Glu99-Ala330), Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May...
| Schlagworte: | BTLA, CD272 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.9 kD |
ab 140,00 €