Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human 2B4 Protein, hFc tag
Artikelnummer: DIM-PME100477.10
Recombinant human 2B4 protein with C-terminal human Fc tag. 2B4(Cys22-Ala216) hFc(Glu99-Ala330), Protein function: Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family, its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the...
| Schlagworte: | CD244, 2B4, SLAMF4, NKR2B4, NAIL, h2B4 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 47.7 kD |
ab 124,00 €
Human GITR Ligand Protein, His tag
Artikelnummer: DIM-PME100478.10
Recombinant human GITR Ligand protein with C-terminal His tag. GITR Ligand(Gln50-Ser177) 6×His, Protein function: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T- cell activation and T-cell proliferation. Important for interactions...
| Schlagworte: | TNFSF18, AITRL, TL6, hGITRL, GITR Ligand |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 15.3 kD |
ab 140,00 €
Human CTLA-4 Protein, hFc tag
Artikelnummer: DIM-PME100479.10
Recombinant human CTLA-4 protein with C-terminal human Fc tag. CTLA-4(Lys36-Asp161) hFc(Glu99-Ala330), Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of...
| Schlagworte: | CTLA4, CD152 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.6 kD |
ab 140,00 €
Human CD30 Protein, His tag
Artikelnummer: DIM-PME100481.10
Recombinant human CD30 protein with C-terminal 6×His tag. CD30(Phe19-Lys379) 6×His tag, Protein function: Receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa- B...
| Schlagworte: | TNFRSF8, CD30, D1S166E, Ki-1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.3 kD |
ab 140,00 €
Human ICOS Protein, hFc tag
Artikelnummer: DIM-PME100484.10
Recombinant human ICOS protein with C-terminal human Fc tag. ICOS(Glu21-Lys140) hFc(Glu99-Ala330), Protein function: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody...
| Schlagworte: | ICOS, CD278, AILIM, Inducible T-cell costimulator |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.7 kD |
ab 133,00 €
Human CD155 Protein, hFc tag
Artikelnummer: DIM-PME100485.10
Recombinant human CD155 protein with C-terminal human Fc tag. CD155(Trp21-Asn343) hFc(Glu99-Ala330), Protein function: Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the...
| Schlagworte: | PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 61.2 kD |
ab 133,00 €
Human CD70 Protein, hFc-His Tag
Artikelnummer: DIM-PME100486.10
Recombinant human CD70 protein with C-terminal human Fc and 6×His tag. CD70(Gln39-Pro193) hFc(Glu99-Ala330) 6×His, Protein function: Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses....
| Schlagworte: | CD70, CD27LG, TNFSF7, TNFSF7G, CD27L |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 44.1 kD |
ab 140,00 €
SARS-CoV-2 (2019-nCoV) S protein RBD, hFc Tag
Artikelnummer: DIM-PME100487.10
Recombinant SARS-CoV-2 (2019-nCoV) S protein RBD protein with C-terminal human Fc tag. S protein RBD(Arg319-Phe541) hFc(Glu99-Ala330), Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2...
| Schlagworte: | S protein RBD, Spike glycoprotein Receptor-binding domain, S glycoprotein RBD, Spike protein RBD, COVID-19 |
| Exprimiert in: | Human cells |
| Ursprungsart: | SARS-CoV-2 |
| MW: | 51.2 kD |
ab 114,00 €
Human ACE2 Protein, His Tag
Artikelnummer: DIM-PME100490.10
Recombinant Human ACE2 Protein with N-terminal 6×His tag. 6×His ACE2(Gln18-Ser740), Protein function: Essential counter-regulatory carboxypeptidase of the renin- angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis...
| Schlagworte: | ACE-2, ACEH, ACE2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 84.4 kD |
ab 114,00 €
SARS-CoV-2 (2019-nCoV) S1 protein NTD, His Tag
Artikelnummer: DIM-PME100491.10
Recombinant SARS-CoV-2 (2019-nCoV) S1 protein NTD with C-terminal 6×His tag. S1 protein NTD(Ser13-Leu303) 6×His tag, Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2 (PubMed:32142651,...
| Schlagworte: | S1 protein NTD, Spike protein S1 NTD, BetaCoV S1-NTD, COVID-19 |
| Exprimiert in: | Human cells |
| Ursprungsart: | SARS-CoV-2 |
| MW: | 33.7 kD |
ab 105,00 €
SARS-CoV-2 (2019-nCoV) S1 protein NTD, mFc Tag
Artikelnummer: DIM-PME100492.10
Recombinant SARS-CoV-2 (2019-nCoV) S1 protein NTD with C-terminal mouse Fc tag. S1 protein NTD(Ser13-Leu303) mFc(Pro99-Lys330), Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2 (PubMed:32142651,...
| Schlagworte: | S1 protein NTD, Spike protein S1 NTD, BetaCoV S1-NTD, COVID-19 |
| Exprimiert in: | Human cells |
| Ursprungsart: | SARS-CoV-2 |
| MW: | 59.1 kD |
ab 120,00 €
SARS-CoV-2 (2019-nCoV) S1 protein NTD, hFc Tag
Artikelnummer: DIM-PME100493.10
Recombinant SARS-CoV-2 (2019-nCoV) S1 protein NTD with C-terminal human Fc tag. S1 protein NTD(Ser13-Leu303) hFc(Glu99-Ala330), Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2 (PubMed:32142651,...
| Schlagworte: | S1 protein NTD, Spike protein S1 NTD, BetaCoV S1-NTD, COVID-19 |
| Exprimiert in: | Human cells |
| Ursprungsart: | SARS-CoV-2 |
| MW: | 59.0 kD |
ab 114,00 €