Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human TweakR Protein, mFc Tag
Artikelnummer: DIM-PME100463.10
Recombinant human TweakR protein with C-terminal mouse Fc tag. TweakR(Glu28-Pro80) mFc(Pro99-Lys330), Protein function: Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. [The...
| Schlagworte: | TNFRSF12A, FGF-inducible 14, FN14, TweakR, CD266 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 31.8 kD |
ab 114,00 €
Human CD7 Protein, mFc Tag
Artikelnummer: DIM-PME100464.10
Recombinant human CD7 protein with C-terminal mouse Fc tag. CD7(Ala26-Pro180) mFc(Pro99-Lys330), Protein function: Not yet known. [The UniProt Consortium]
| Schlagworte: | CD7, GP40, TP41, LEU-9, Tp40 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 42.7 kD |
ab 105,00 €
Human TNFRSF10B Protein, mFc Tag
Artikelnummer: DIM-PME100465.10
Recombinant human TNFRSF10B protein with C-terminal mouse Fc tag. TNFRSF10B (Ile56-Glu182) mFc(Pro99-Lys330), Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex...
| Schlagworte: | TNFRSF10B, TRAILR2, TRAIL-R2, CD262, DR5, KILLER, TRICK2, ZTNFR9, TRICKB |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 40.5 kD |
ab 114,00 €
Human CD200 Protein, His Tag
Artikelnummer: DIM-PME100466.10
Recombinant human CD200 protein with C-terminal 6×His tag. CD200(Gln31-Gly232) 6×His tag, Protein function: Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. [The UniProt Consortium]
| Schlagworte: | CD200, MOX1, MOX2, MRC, OX-2, My033 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 23.3 kD |
ab 105,00 €
Human IL17RA Protein, His Tag
Artikelnummer: DIM-PME100468.10
Recombinant human IL17RA protein with C-terminal 6×His tag. IL17RA(Leu33-Trp320) 6×His tag, Protein function: Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A (PubMed:17911633,...
| Schlagworte: | CD217, CDw217, IL-17RA, IL17R, CANDF5, hIL-17R |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 34.3 kD |
ab 120,00 €
Human CD34 Protein, His Tag
Artikelnummer: DIM-PME100469.10
Recombinant human CD34 protein with C-terminal 6×His tag. CD34(Ser32-Thr290) 6×His tag, Protein function: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the...
| Schlagworte: | CD34 Molecule |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 28.3 kD |
ab 105,00 €
Human CD5 Protein, His Tag
Artikelnummer: DIM-PME100470.10
Recombinant human CD5 protein with C-terminal 6×His tag. CD5(Arg25-Pro372) 6×His tag, Protein function: May act as a receptor in regulating T-cell proliferation. [The UniProt Consortium]
| Schlagworte: | CD5, LEU1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.5 kD |
ab 105,00 €
Human CD162 Protein, His Tag
Artikelnummer: DIM-PME100471.10
Recombinant Human CD162 protein with C-terminal 6×His tag. CD162(Leu18-Cys320) 6×His tag, Protein function: A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in...
| Schlagworte: | PSGL-1, PSGL1, CD162, SELPLG, Selectin P ligand |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 31.4 kD |
ab 124,00 €
Human B7-1 Protein, hFc Tag
Artikelnummer: DIM-PME100473.10
Recombinant human B7-1 protein with C-terminal human Fc tag. B7-1(Val35-Asn242) hFc(Glu99-Ala330), Protein function: Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and...
| Schlagworte: | CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 50.0 kD |
ab 140,00 €
Human B7-2 Protein, hFc Tag
Artikelnummer: DIM-PME100474.10
Recombinant human B7-2 protein with C-terminal human Fc tag. B7-2(Leu26-Pro247) hFc(Glu99-Ala330), Protein function: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell...
| Schlagworte: | CD86, B7-2, B70, CD28LG2, LAB72, MGC34413 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 51.5 kD |
ab 140,00 €
Human CD27 Protein, hFc Tag
Artikelnummer: DIM-PME100475.10
Recombinant human CD27 protein with C-terminal human Fc tag. CD27(Ala20-Arg191) hFc(Glu99-Ala330), Protein function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. [The UniProt Consortium]
| Schlagworte: | CD27, TNFRSF7, S152, T14, Tp55 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 45.3 kD |
ab 140,00 €
Human CD48 Protein, hFc Tag
Artikelnummer: DIM-PME100476.10
Recombinant human CD48 protein with C-terminal human Fc. CD48(Gln27-Ser220) hFc(Glu99-Ala330), Protein function: Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. [The UniProt Consortium]
| Schlagworte: | CD48, BCM1, SLAMF2, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 48.5 kD |
ab 120,00 €