Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human MICA Protein, His Tag
Artikelnummer: DIM-PME100349.10
Recombinant Human MICA Protein with C-terminal 6×His tag. MICA (Glu24-Trp307) 6×His tag, Protein function: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. [The...
| Schlagworte: | MIC-A, PERB11.1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 33.5 kD |
ab 124,00 €
Human MIF Protein, hFc Tag
Artikelnummer: DIM-PME100350.10
Recombinant human MIF protein with C-terminal hFc tag. MIF(Pro2-Ala115) hFc(Glu99-Ala330), Protein function: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. [The...
| Schlagworte: | GIF, GLIF, MMIF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 38.5 kD |
ab 120,00 €
Human MUC16(13810-14451) Protein, His Tag
Artikelnummer: DIM-PME100358.10
Recombinant human MUC16(13810-14451) Protein with C-terminal 10×His tag. MUC16(Pro13810-Pro14451) 10×His tag, Protein function: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. [The UniProt Consortium]
| Schlagworte: | CA125 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 73.2 kD |
ab 110,00 €
Human P2RX7 Protein, hFc Tag
Artikelnummer: DIM-PME100377.10
Recombinant human P2RX7 protein with N-terminal human Fc tag. hFc(Glu99-Ala330) P2RX7(Ser47-Val334), Protein function: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in...
| Schlagworte: | P2X7 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 59.2 kD |
ab 120,00 €
Human ROR1 Protein, His Tag
Artikelnummer: DIM-PME100399.10
Recombinant Human ROR1 Protein with C-terminal 6×His tag. ROR1(Gln30-Glu403) 6×His tag, Protein function: Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the...
| Schlagworte: | ROR1, NTRKR1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 42.8 kD |
ab 120,00 €
Human SIGLEC15 Protein, mFc-His Tag
Artikelnummer: DIM-PME100402.10
Recombinant human SIGLEC15 protein with C-terminal mouse Fc and 6×His tag. SIGLEC15(Phe20-Thr263) mFc(Pro99-Lys330) 6×His tag, Protein function: Binds sialylated glycoproteins. [The UniProt Consortium]
| Schlagworte: | CD33 antigen-like 3, SIGLEC-15, CD33L3, sialic acid-binding Ig-like lectin 15, Siglec15, Siglec-15 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 53.6 kD |
ab 120,00 €
Human TLR3 Protein, mFc Tag
Artikelnummer: DIM-PME100429.10
Recombinant human TLR3 protein with C-terminal mouse Fc tag. TLR3(Ser24-Leu704) mFc(Pro99-Lys330), Protein function: Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is...
| Schlagworte: | TLR3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 103.5 kD |
ab 120,00 €
Human TYRO3 Protein, His Tag
Artikelnummer: DIM-PME100450.10
Recombinant human TYRO3 protein with C-terminal 6×His tag. TYRO3(Ala41-Ser428) 6×His tag, Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell...
| Schlagworte: | BYK, Dtk, Etk-2, Rek, RSE, Sky, Tif |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 42.4 kD |
ab 105,00 €
SARS-CoV-2 (2019-nCoV) Nucleocapsid, N-His Tag
Artikelnummer: DIM-PME100459.10
SARS-CoV-2 (2019-nCoV) Nucleocapsid, His Tag. 6*His Tag Nucleocapsid protein(Met1-Ala419), Protein function: Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M....
| Schlagworte: | Nucleocapsid protein, NP, Protein N |
| Exprimiert in: | E.coli |
| Ursprungsart: | SARS-CoV-2 |
| MW: | 49.4 kD |
ab 124,00 €
SARS-CoV-2 (2019-nCoV) S protein RBD, mFc-His Tag
Artikelnummer: DIM-PME100460.10
Recombinant SARS-CoV-2 (2019-nCoV) S protein RBD with C-terminal mouse Fc and 6×His tag. S protein RBD(Arg319-Phe541) mFc(Pro99-Lys330) 6×His tag, Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host...
| Schlagworte: | S protein RBD, Spike glycoprotein Receptor-binding domain, S glycoprotein RBD, Spike protein RBD, COVID-19 |
| Exprimiert in: | Human cells |
| Ursprungsart: | SARS-CoV-2 |
| MW: | 52.2 kD |
ab 120,00 €
Human PD-1 Protein, His tag
Artikelnummer: DIM-PME100461.10
Recombinant human PD-1 protein with C-terminal 6×His tag. PD-1(Leu25-Gln167) 6×His tag, Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands...
| Schlagworte: | PDCD1, PD1, CD279, SLEB2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 16.8 kD |
ab 105,00 €
Human PD-1 Protein, hFc-His tag
Artikelnummer: DIM-PME100462.10
Recombinant human PD-1 protein with C-terminal human Fc and 6×His tag. PD-1(Leu25-Gln167) hFc(Glu99-Ala330) 6×His tag, Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals...
| Schlagworte: | PDCD1, PD1, CD279, SLEB2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 42.9 kD |
ab 140,00 €