Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human FOLR2 Protein, mFc Tag
Artikelnummer: DIM-PME100250.10
Recombinant human FOLR2 protein with C-terminal mouse Fc tag. FOLR2(Thr17-His228) mFc(Pro99-Lys330), Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid...
| Schlagworte: | BETA-HFR, FBP, FBP/PL-1, FOLR1, FR-BETA, FR-P3, FRbeta |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 50.7 kD |
ab 133,00 €
Human GUCY2C Protein, His Tag
Artikelnummer: DIM-PME100262.10
Recombinant human GUCY2C protein with C-terminal 6×His tag. GUCY2C(Ser24-Gln430) 6×His tag, Protein function: Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and...
| Schlagworte: | DIAR6, GC-C, GUC2C, MECIL, MUCIL, STAR |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 46.8 kD |
ab 120,00 €
Human HVEM Protein, His Tag
Artikelnummer: DIM-PME100273.10
Recombinant Human HVEM Protein with C-terminal 6×His tag. HVEM(Leu39-Val202) 6×His tag, Protein function: Receptor for four distinct ligands: The TNF superfamily members TNFSF14/LIGHT and homotrimeric LTA/lymphotoxin-alpha and the immunoglobulin superfamily members BTLA and CD160, altogether defining a complex...
| Schlagworte: | ATAR, CD270, HVEA, HVEM, LIGHTR, TR2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 18.2 kD |
ab 140,00 €
Human IL13RA1 Protein, His Tag
Artikelnummer: DIM-PME100291.10
Recombinant Human IL13RA1 Protein with C-terminal 6×His tag. IL13RA1(Gly22-Thr343) 6×His tag, Protein function: Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for...
| Schlagworte: | CD213A1, CT19, IL-13Ra, NR4 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 37.7 kD |
ab 124,00 €
Human IL2 Protein, hFc Tag
Artikelnummer: DIM-PME100300.10
Recombinant Human IL2 Protein with C-terminal human Fc tag. IL2(Ala21-Thr153) hFc(Glu99-Ala330), Protein function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate...
| Schlagworte: | IL-2, lymphokine, TCGF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 41.6 kD |
ab 124,00 €
Human IL21R Protein, hFc Tag
Artikelnummer: DIM-PME100301.10
Recombinant human IL21R protein with C-terminal human Fc tag. IL21R(Cys20-Glu232) hFc(Glu99-Ala330), Protein function: This is a receptor for interleukin-21. [The UniProt Consortium]
| Schlagworte: | CD360, IMD56, NILR |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 50.7 kD |
ab 124,00 €
Human ITGB1 Protein, hFc Tag
Artikelnummer: DIM-PME100311.10
Recombinant human ITGB1 protein with C-terminal human Fc tag. ITGB1(Gln21-Asp728) hFc(Glu99-Ala330), Protein function: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence...
| Schlagworte: | GPIIA, CD29, VLA-4 subunit beta |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 104.5 kD |
ab 114,00 €
Human KI67(1206-1238) Protein, hFc Tag
Artikelnummer: DIM-PME100315.10
Recombinant human KI67(1206-1238) Protein with C-terminal human Fc tag. KI67(Gly1206-Glu1238) hFc(Glu99-Ala330), Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic...
| Schlagworte: | KIA, MIB-, MIB-1, PPP1R105, MKI67 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 29.8 kD |
ab 146,00 €
Human KIR2DL3 Protein, His Tag
Artikelnummer: DIM-PME100319.10
Recombinant Human KIR2DL3 Protein with C-terminal 6XHis tag. KIR2DL3(His22-His245) 6×His tag, Protein function: Receptor on natural killer (NK) cells for HLA-C alleles (HLA- Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis. [The UniProt Consortium]
| Schlagworte: | p58, NKAT, GL183, NKAT2, CD158b, KIR2DL, NKAT2A, NKAT2B, CD158B2, KIR-K7b, KIR-K7c, KIR2DS5, KIRCL23, KIR-023GB |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 25.4 kD |
ab 110,00 €
Human KLRG1 Protein, hFc Tag
Artikelnummer: DIM-PME100321.10
Recombinant Human KLRG1 protein with N-terminal human Fc. hFc(Glu99-Ala330) KLRG1(Leu60-Phe195), Protein function: Plays an inhibitory role on natural killer (NK) cells and T- cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical...
| Schlagworte: | CLEC15A, MAFA, MAFAL |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 41.6 kD |
ab 124,00 €
Human KRAS Protein, mFc Tag
Artikelnummer: DIM-PME100322.10
Recombinant human KRAS protein with C-terminal mouse Fc tag. KRAS(Thr2-Cys185) mFc(Pro99-Lys330), Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621). Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in...
| Schlagworte: | C-K-RAS, c-Ki-ras2, CFC2, K-Ras, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RALD, RASK2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 47.1 kD |
ab 105,00 €
Human MERTK Protein, His Tag
Artikelnummer: DIM-PME100344.10
Recombinant human MERTK Protein with C-terminal 10×His tag. MERTK(Ala21-Ile505) 10×His tag, Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes...
| Schlagworte: | MER, RP38, c-Eyk, c-mer, Tyro12 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 54.0 kD |
ab 110,00 €