Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human CD171 Protein, His Tag
Artikelnummer: DIM-PME100173.10
Recombinant Human CD171 Protein with C-terminal 6×His tag. CD171(Ile20-Glu1120) 6×His tag, Protein function: Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes,...
| Schlagworte: | CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 124.0 kD |
ab 105,00 €
Human CD36 Protein, hFc Tag
Artikelnummer: DIM-PME100187.10
Recombinant Human CD36 Protein with C-terminal human Fc tag. CD36(Gly30-Asn439) hFc(Glu99-Ala330), Protein function: Multifunctional glycoprotein that acts as receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic...
| Schlagworte: | BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 72.8 kD |
ab 133,00 €
Human CD40 Ligand Protein, hFc Tag
Artikelnummer: DIM-PME100192.10
Recombinant human CD40 Ligand Protein with N-terminal Human Fc tag. hFc(Glu99-Ala330) CD40 Ligand(Met113-Leu261), Protein function: Cytokine that acts as a ligand to CD40/TNFRSF5 (PubMed:1280226, PubMed:31331973). Costimulates T-cell proliferation and cytokine production (PubMed:8617933). Its cross-linking on...
| Schlagworte: | CD40LG, CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 42.3 kD |
ab 114,00 €
Human CD56 Protein, His Tag
Artikelnummer: DIM-PME100194.10
Recombinant Human CD56 Protein with C-terminal 6×His tag. CD56(Leu20-Gly708) 6×His tag, Protein function: This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. [The UniProt Consortium]
| Schlagworte: | NCAM1, CD56, MSK39, NCAM |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 77.0 kD |
ab 105,00 €
Human CDH17(567-667) Protein, hFc Tag
Artikelnummer: DIM-PME100199.10
Recombinant human CDH17(567-667) Protein with C-terminal human Fc tag. CDH17(Ser567-Leu667) hFc(Glu99-Ala330), Protein function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the...
| Schlagworte: | CDH16, HPT-1, HPT1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 37.0 kD |
ab 110,00 €
Human CLEC2D Protein, N-His Tag
Artikelnummer: DIM-PME100208.10
Recombinant Human CLEC2D Protein with N-terminal 6×His tag. 6×His CLEC2D(Arg60-Val191), Protein function: Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:20843815, PubMed:16339513). Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656). Inhibits bone...
| Schlagworte: | CLAX, LLT1, OCIL |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 16.2 kD |
ab 105,00 €
Human CRLF2 Protein, His Tag
Artikelnummer: DIM-PME100213.10
Recombinant Human CRLF2 Protein with C-terminal 6XHis tag. CRLF2(Gln23-Lys231) 6×His tag, Protein function: Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2....
| Schlagworte: | CRL2, TSLPR, CRLF2Y |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 25.0 kD |
ab 102,00 €
Human CSPG4 Protein, His Tag
Artikelnummer: DIM-PME100217.10
Recombinant Human CSPG4 Protein with C-terminal 6×His tag.. CSPG4(Ala30-Ser2224) 6×His tag, Protein function: Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse...
| Schlagworte: | CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 237.7 kD |
ab 114,00 €
Human CXCR7 Protein, hFc Tag
Artikelnummer: DIM-PME100228.10
Recombinant human CXCR7 protein with C-terminal human Fc tag. CXCR7(Met1-Lys40) hFc(Glu99-Ala330), Protein function: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting...
| Schlagworte: | Atypical chemokine receptor 3, CXC-R7, CXCR-7, Chemokine orphan receptor 1, G-protein coupled receptor 159, RDC-1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 31.0 kD |
ab 105,00 €
Human DKK1 Protein, hFc Tag
Artikelnummer: DIM-PME100230.10
Recombinant human DKK1 Protein with C-terminal human Fc tag. DKK1(Thr32-His266) hFc(Glu99-Ala330), Protein function: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6...
| Schlagworte: | DKK-1, SK |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 51.9 kD |
ab 105,00 €
Human EPHA2 Protein, His Tag
Artikelnummer: DIM-PME100238.10
Recombinant Human EPHA2 Protein with C-terminal 6×His tag. EPHA2 (Ala24-Asn534) 6×His tag, Protein function: Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The...
| Schlagworte: | ARCC2, CTPA, CTPP1, CTRCT6, ECK |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 57.0 kD |
ab 114,00 €
Human FOLR1 Protein, His Tag
Artikelnummer: DIM-PME100249.10
Recombinant Human FOLR1 Protein with C-terminal 6×His tag. FOLR1(Arg25-Ser234) 6×His tag, Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at...
| Schlagworte: | FBP, FOLR, FRalpha |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 25.5 kD |
ab 114,00 €