Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
Mehr Informationen unter: www.dimabio.com
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-B7-H2(prezalumab biosimilar) mAb
Artikelnummer: DIM-BME100081.100
Protein function: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory...
| Schlagworte: | Anti-ICOSLG, Anti-B7-H2, Anti-B7H2, Anti-B7RP-1, Anti-B7RP1, Anti-CD275, Anti-GL50, Anti-ICOS-L, Anti-ICOSL, Anti-LICOS,... |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CLDN6 (IMAB027) mAb
Artikelnummer: DIM-BME100082.100
Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space. [The UniProt Consortium]
| Schlagworte: | Anti-Claudin 6, Anti-Claudin-6, Anti-Skullin, Anti-CLDN6 (IMAB027) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-GPC3(codrituzumab biosimilar) mAb
Artikelnummer: DIM-BME100083.100
Protein function: Cell surface proteoglycan that bears heparan sulfate (PubMed:14610063). Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH...
| Schlagworte: | Anti-DGSX, Anti-GTR2-2, Anti-MXR7, Anti-OCI-5, Anti-SDYS, Anti-SGB, Anti-SGBS, Anti-SGBS1, Anti-GPC3(codrituzumab... |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL7RA(lusvertikimab biosimilar) mAb
Artikelnummer: DIM-BME100084.100
Protein function: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). [The UniProt Consortium]
| Schlagworte: | Anti-CD127, Anti-CDW127, Anti-IL-7R-alpha, Anti-IL7RA, Anti-ILRA, Anti-IL7RA(lusvertikimab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-NKG2A(monalizumab biosimilar) mAb
Artikelnummer: DIM-BME100085.100
Protein function: Immune inhibitory receptor involved in self-nonself discrimination. In complex with KLRD1 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class...
| Schlagworte: | Anti-CD159A, Anti-NKG2, Anti-NKG2A, Anti-NKG2A(monalizumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Human 5T4 Protein, His Tag
Artikelnummer: DIM-PME100123.10
Recombinant Human 5T4 Protein with C-terminal 6×His tag. 5T4(Ser32-Ser355) 6×His tag, Protein function: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. [The UniProt Consortium]
| Schlagworte: | 5T4, 5T4AG, M6P1, WAIF1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 36.1 kD |
ab 105,00 €
Human ADAM9 Protein, hFc Tag
Artikelnummer: DIM-PME100128.10
Recombinant human ADAM9 Protein with C-terminal Human Fc tag. ADAM9(Ala29-Asp697) hFc(Glu99-Ala330), Protein function: Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and...
| Schlagworte: | CORD9, MCMP, MDC9, Mltng |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 100.1 kD |
ab 124,00 €
Human ADORA2A Protein, hFc Tag
Artikelnummer: DIM-PME100130.10
Recombinant human ADORA2A Protein with C-terminal Human Fc tag. ADORA2A(Met1-Ser7) (Ser67-His75) (Asn144-Pro173) (Cys259-Pro266) hFc(Glu99-Ala330), Protein function: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. [The UniProt Consortium]
| Schlagworte: | A2aR, ADORA2, RDC8 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 31.7 kD |
ab 105,00 €
Human ALK Protein, hFc Tag
Artikelnummer: DIM-PME100134.10
Recombinant Human ALK Protein with C-terminal human Fc tag. ALK(Val19-Ser1038) hFc(Glu99-Ala330), Protein function: Neuronal receptor tyrosine kinase that is essentially and transiently expressed in specific regions of the central and peripheral nervous systems and plays an important role in the genesis and...
| Schlagworte: | CD246, NBLST3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 136.4 kD |
ab 105,00 €
Human CA9 Protein, His Tag
Artikelnummer: DIM-PME100152.10
Recombinant Human CA9 Protein with C-terminal 6×His tag. CA9(Gln38-Asp414) 6×His tag, Protein function: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia....
| Schlagworte: | CAIX, MN |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 41.5 kD |
ab 114,00 €
Human CB2 (1-33) Protein, hFc Tag
Artikelnummer: DIM-PME100156.10
Recombinant Human CB2 Protein with C-terminal human Fc tag. CB2(Met1-Lys33) hFc(Glu99-Ala330), Protein function: Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone...
| Schlagworte: | CB-2, CB2, CX5, CNR2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 29.8 kD |
ab 105,00 €
Human CCL20 Protein, hFc Tag
Artikelnummer: DIM-PME100159.10
Recombinant Human CCL20 Protein with C-terminal human Fc tag. CCL20(Ala27-Met96) hFc(Glu99-Ala330), Protein function: Acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions...
| Schlagworte: | CKb4, Exodus, LARC, MIP-3-alpha, MIP-3a, MIP3A, SCYA20, ST38 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 34.3 kD |
ab 120,00 €