Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-Human IgG antibody(2D9), Rabbit mAb
Artikelnummer: DIM-DME101030.10
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
DiTagTM pH sensitive IgG labeling reagent
Artikelnummer: DIM-AME100001.10
| Anwendung: | ADC Assay Reagents |
| MW: | 33.4 kD |
ab 923,00 €
DiTagTM pH sensitive IgG labeling reagent plus
Artikelnummer: DIM-AME100002.10
| Anwendung: | ADC Assay Reagents |
| MW: | 21.8 kD |
ab 402,00 €
Anti-CD47 (magrolimab biosimilar) mAb
Artikelnummer: DIM-BME100001.100
Protein function: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells...
| Schlagworte: | Anti-CD47, Anti-MER6, Anti-IAP, Anti-CD47 (magrolimab biosimilar) mAb |
| Wirt: | Chimeric Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CS1 (elotuzumab biosimilar) mAb
Artikelnummer: DIM-BME100002.100
Protein function: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and...
| Schlagworte: | Anti-CS1, Anti-CD319, Anti-SLAMF7, Anti-CRACC, Anti-CS1 (elotuzumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD123 (talacotuzumab biosimilar) mAb
Artikelnummer: DIM-BME100003.100
Protein function: This is a receptor for interleukin-3. [The UniProt Consortium]
| Schlagworte: | Anti-CD123, Anti-IL3R, Anti-IL3RA, Anti-CD123 (talacotuzumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD38 (daratumumab biosimilar) mAb
Artikelnummer: DIM-BME100004.100
Protein function: Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. [The UniProt Consortium]
| Schlagworte: | Anti-CD38, Anti-T10, Anti-ADPRC1, Anti-CD38 (daratumumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD70 (vorsetuzumab biosimilar) mAb
Artikelnummer: DIM-BME100005.100
Protein function: Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses. Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells....
| Schlagworte: | Anti-CD70, Anti-CD27L, Anti-CD27LG, Anti-TNFSF7, Anti-CD70 (vorsetuzumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-PD-1 (pembrolizumab biosimilar) mAb
Artikelnummer: DIM-BME100006.100
Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell receptor (TCR) engagement,...
| Schlagworte: | Anti-PDCD1, Anti-PD1, Anti-CD279, Anti-SLEB2, Anti-PD-1 (pembrolizumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL6 (siltuximab biosimilar) mAb
Artikelnummer: DIM-BME100007.100
Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and...
| Schlagworte: | Anti-IL6, Anti-Interleukin-6, Anti-BSF2, Anti-HSF, Anti-IFNB2, Anti-IL6 (siltuximab biosimilar) mAb |
| Wirt: | Chimeric |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-TIM3 (cobolimab biosimilar) mAb
Artikelnummer: DIM-BME100008.100
Protein function: Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand (PubMed:24825777). Regulates...
| Schlagworte: | Anti-HAVCR2, Anti-TIM3, Anti-TIMD3, Anti-FLJ14428, Anti-KIM3, Anti-TIM3 (cobolimab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-PDL1 (atezolizumab biosimilar) mAb
Artikelnummer: DIM-BME100009.100
Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443,...
| Schlagworte: | Anti-PD-L1, Anti-CD274, Anti-B7-H1, Anti-PDCD1L1, Anti-PDCD1LG1, Anti-PDL1 (atezolizumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €