Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-PSMA(rosopatamab biosimilar) mAb
Artikelnummer: DIM-BME100128.100
Protein function: Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide,...
| Schlagworte: | Anti-FGCP, Anti-FOLH, Anti-GCP2, Anti-GCPII, Anti-mGCP, Anti-NAALAD1, Anti-NAALAdase, Anti-PSM, Anti-PSMA(rosopatamab... |
| Wirt: | Chimeric |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD73(uliledlimab biosimilar) mAb
Artikelnummer: DIM-BME100129.100
Protein function: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. [The UniProt Consortium]
| Schlagworte: | Anti-NT5E, Anti-5'-Nucleotidase, Anti-5'-NT, Anti-NT5, Anti-NTE, Anti-CD73(uliledlimab biosimilar) mAb |
| Wirt: | Chimeric Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-GM-CSF(plonmarlimab biosimilar) mAb
Artikelnummer: DIM-BME100130.100
Protein function: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. [The UniProt Consortium]
| Schlagworte: | Anti-CSF, Anti-CSF2, Anti-GM-CSF(plonmarlimab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-FLT1(icrucumab biosimilar) mAb
Artikelnummer: DIM-BME100131.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a...
| Schlagworte: | Anti-FLT, Anti-FLT-1, Anti-VEGFR-1, Anti-VEGFR1, Anti-FLT1(icrucumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL20(fletikumab biosimilar) mAb
Artikelnummer: DIM-BME100132.100
Protein function: Proinflammatory and angiogenic cytokine that may be involved in epidermal function and psoriasis. Angiogenic and proliferative activities are antagonized by IL10. May act through STAT3. [The UniProt Consortium]
| Schlagworte: | Anti-IL-20, Anti-Cytokine Zcyto10, Anti-IL20(fletikumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CXCL10(eldelumab biosimilar) mAb
Artikelnummer: DIM-BME100133.100
Protein function: Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (PubMed:7540647, PubMed:11157474, PubMed:22652417). Plays thereby an...
| Schlagworte: | Anti-Gamma-IP10, Anti-IP-10, Anti-SCYB10, Anti-INP10, Anti-CXCL10(eldelumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-KIR2DL2(lirilumab biosimilar) mAb
Artikelnummer: DIM-BME100134.100
Protein function: Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis. [The UniProt Consortium]
| Schlagworte: | Anti-CD158b, Anti-CD158B1, Anti-NKAT-6, Anti-NKAT6, Anti-p58.2, Anti-KIR2DL2(lirilumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-APP(aducanumab biosimilar) mAb
Artikelnummer: DIM-BME100136.100
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis (PubMed:25122912). Involved in cell mobility and...
| Schlagworte: | Anti-AAA, Anti-ABETA, Anti-ABPP, Anti-AD1, Anti-APPI, Anti-CTFgamma, Anti-CVAP, Anti-PN-II, Anti-PN2, Anti-preA4,... |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL17A(secukinumab biosimilar) mAb
Artikelnummer: DIM-BME100137.100
Protein function: Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (PubMed:24120361). Signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter. This...
| Schlagworte: | Anti-CTLA-8, Anti-CTLA8, Anti-IL-17, Anti-IL-17A, Anti-IL17, Anti-IL17A(secukinumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-TFRC(pabinafusp alfa biosimilar) mAb
Artikelnummer: DIM-BME100138.100
Protein function: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed:26214738). Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH...
| Schlagworte: | Anti-TR, Anti-TfR, Anti-TfR1, Anti-Trfr, Anti-T9, Anti-p90, Anti-CD71, Anti-TFRC(pabinafusp alfa biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-HGF(ficlatuzumab biosimilar) mAb
Artikelnummer: DIM-BME100139.100
Protein function: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. [The UniProt Consortium]
| Schlagworte: | Anti-Hepatopoietin-A, Anti-SF, Anti-HPTA, Anti-HGF(ficlatuzumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD3E(DIMA BM323) mAb
Artikelnummer: DIM-BME100140.100
Protein function: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z....
| Schlagworte: | Anti-CD3e, Anti-T3E, Anti-CD3E(DIMA BM323) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €