Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-B7-2 antibody(DM86), Rabbit mAb
Artikelnummer: DIM-DME100086.10
Protein function: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is...
| Schlagworte: | Anti-CD86, Anti-B7-2, Anti-B70, Anti-CD28LG2, Anti-LAB72, Anti-MGC34413, Anti-B7-2 antibody(DM86), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-PSCA antibody(DM87), Rabbit mAb
Artikelnummer: DIM-DME100087.10
Protein function: May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. [The UniProt Consortium]
| Schlagworte: | Anti-PSCA, Anti-UNQ206, Anti-PRO232, Anti-PSCA antibody(DM87), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-NKp30 antibody(DM88), Rabbit mAb
Artikelnummer: DIM-DME100088.10
Protein function: Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of...
| Schlagworte: | Anti-NCR3, Anti-CD337, Anti-NKp30, Anti-1C7, Anti-LY117, Anti-MALS, Anti-NKp30 antibody(DM88), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GPRC5D antibody(DM91), Rabbit mAb
Artikelnummer: DIM-DME100091.10
| Schlagworte: | Anti-GPRC5D, Anti-GPRC5D antibody(DM91), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IL15RA antibody(DM206), Rabbit mAb
Artikelnummer: DIM-DME100206.10
Protein function: High-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed:15123770). In neutrophils,...
| Schlagworte: | Anti-CD215, Anti-IL15RA antibody(DM206), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CXCR3 antibody(DM208), Rabbit mAb
Artikelnummer: DIM-DME100208.10
Protein function: [Isoform 1]: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G- protein signaling pathway (PubMed:12782716). Binds to CCL21. Probably promotes cell chemotaxis response....
| Schlagworte: | Anti-CD182, Anti-CD183, Anti-CKR-L2, Anti-CMKAR3, Anti-GPR9, Anti-IP10-R, Anti-Mig-R, Anti-MigR, Anti-CXCR3... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-NRG1 antibody(DM209), Rabbit mAb
Artikelnummer: DIM-DME100209.10
Protein function: Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation...
| Schlagworte: | Anti-ARIA, Anti-GGF, Anti-GGF2, Anti-HGL, Anti-HRG, Anti-HRG1, Anti-HRGA, Anti-MST131, Anti-MSTP131, Anti-NDF,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-DKK1 antibody(DM210), Rabbit mAb
Artikelnummer: DIM-DME100210.10
Protein function: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:22000856). DKKs play an important role in vertebrate development, where they locally inhibit Wnt...
| Schlagworte: | Anti-DKK-1, Anti-SK, Anti-DKK1 antibody(DM210), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD43 antibody(DM211), Rabbit mAb
Artikelnummer: DIM-DME100211.10
Protein function: Predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration. Positively regulates T-cell trafficking to lymph-nodes via its association with ERM proteins (EZR, RDX and MSN)....
| Schlagworte: | Anti-CD43, Anti-GALGP, Anti-GPL115, Anti-LSN, Anti-CD43 antibody(DM211), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD47 antibody(DM212), Rabbit mAb
Artikelnummer: DIM-DME100212.10
Protein function: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells...
| Schlagworte: | Anti-CD47, Anti-MER6, Anti-IAP, Anti-OA3, Anti-CD47 antibody(DM212), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-UCHL1 antibody(DM214), Rabbit mAb
Artikelnummer: DIM-DME100214.10
Protein function: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (Probable). This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (PubMed:9774100, PubMed:8639624, PubMed:12408865,...
| Schlagworte: | Anti-HEL-117, Anti-HEL-S-53, Anti-NDGOA, Anti-PARK5, Anti-PGP 9.5, Anti-PGP9.5, Anti-PGP95, Anti-SPG79, Anti-Uch-L1,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GFAP(68-377) antibody(DM216), Rabbit mAb
Artikelnummer: DIM-DME100216.10
Protein function: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. [The UniProt Consortium]
| Schlagworte: | Anti-ALXDRD, Anti-GFAP(68-377) antibody(DM216), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €