Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-CD138 antibody(DM45), Rabbit mAb
Artikelnummer: DIM-DME100044.10
Protein function: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). [The UniProt Consortium]
| Schlagworte: | Anti-SDC1, Anti-Syndecan-1, Anti-CD138, Anti-SYND1, Anti-SDC, Anti-CD138 antibody(DM45), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-ACE2 antibody(DM47), Rabbit mAb
Artikelnummer: DIM-DME100046.10
Protein function: Essential counter-regulatory carboxypeptidase of the renin- angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis (PubMed:27217402). Converts angiotensin I to angiotensin 1- 9, a nine-amino acid peptide with...
| Schlagworte: | Anti-ACE-2, Anti-ACEH, Anti-ACE2, Anti-ACE2 antibody(DM47), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-ACE2 antibody(DM48), Rabbit mAb
Artikelnummer: DIM-DME100047.10
Protein function: Essential counter-regulatory carboxypeptidase of the renin- angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis (PubMed:27217402). Converts angiotensin I to angiotensin 1- 9, a nine-amino acid peptide with...
| Schlagworte: | Anti-ACE-2, Anti-ACEH, Anti-ACE2, Anti-ACE2 antibody(DM48), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CTLA-4 antibody(DM50), Rabbit mAb
Artikelnummer: DIM-DME100049.10
Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Schlagworte: | Anti-CTLA4, Anti-CD152, Anti-CTLA-4 antibody(DM50), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CTLA-4 antibody(DM51), Rabbit mAb
Artikelnummer: DIM-DME100050.10
Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Schlagworte: | Anti-CTLA4, Anti-CD152, Anti-CTLA-4 antibody(DM51), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GITR Ligand antibody(DM52), Rabbit mAb
Artikelnummer: DIM-DME100052.10
Protein function: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T- cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers...
| Schlagworte: | Anti-TNFSF18, Anti-AITRL, Anti-TL6, Anti-hGITRL, Anti-GITR Ligand, Anti-GITR Ligand antibody(DM52), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-B7-H3 antibody(DM53), Rabbit mAb
Artikelnummer: DIM-DME100053.10
Protein function: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant...
| Schlagworte: | Anti-B7-H3, Anti-CD276, Anti-B7 homolog 3, Anti-B7H3, Anti-B7-H3 antibody(DM53), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Biotinylated Anti-B7-H3 antibody(DM53), Rabbit mAb
Artikelnummer: DIM-DME100053B.10
Protein function: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant...
| Schlagworte: | Anti-B7-H3, Anti-CD276, Anti-B7 homolog 3, Anti-B7H3, Biotinylated Anti-B7-H3 antibody(DM53), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 203,00 €
Anti-SARS-CoV-2 RBD antibody(DM54), Rabbit mAb
Artikelnummer: DIM-DME100054.10
Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2 (PubMed:32142651, PubMed:33607086, PubMed:32155444). When S2/S2' has been cleaved, binding to the receptor triggers direct fusion at the cell...
| Schlagworte: | Anti-SARS-CoV-2 RBD, Anti-SARS-CoV-2 RBD antibody(DM54), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | SARS-CoV-2 |
ab 145,00 €
Anti-SARS-CoV-2 RBD antibody(DM55), Rabbit mAb
Artikelnummer: DIM-DME100055.10
Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2 (PubMed:32142651, PubMed:33607086, PubMed:32155444). When S2/S2' has been cleaved, binding to the receptor triggers direct fusion at the cell...
| Schlagworte: | Anti-SARS-CoV-2 RBD, Anti-SARS-CoV-2 RBD antibody(DM55), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | SARS-CoV-2 |
ab 145,00 €
Anti-CD27 antibody(DM57), Rabbit mAb
Artikelnummer: DIM-DME100057.10
Protein function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. [The UniProt Consortium]
| Schlagworte: | Anti-CD27, Anti-TNFRSF7, Anti-S152, Anti-T14, Anti-Tp55, Anti-CD27 antibody(DM57), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD27 antibody(DM58), Rabbit mAb
Artikelnummer: DIM-DME100058.10
Protein function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. [The UniProt Consortium]
| Schlagworte: | Anti-CD27, Anti-TNFRSF7, Anti-S152, Anti-T14, Anti-Tp55, Anti-CD27 antibody(DM58), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €