Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-FZD4 antibody(10E10), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101111.10
Protein function: Receptor for Wnt proteins (PubMed:30135577). Most frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin (CTNNB1) and activation of Wnt target...
| Schlagworte: | Anti-CD344, Anti-EVR1, Anti-FEVR, Anti-Fz-4, Anti-Fz4, Anti-FZD4S, Anti-FzE4, Anti-GPCR, Anti-hFz4, Anti-FZD4... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-NCR1 antibody(2C10), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101112.10
Protein function: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. [The UniProt Consortium]
| Schlagworte: | Anti-CD335, Anti-LY94, Anti-NK-p46, Anti-NKP46, Anti-NCR1 antibody(2C10), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TIM-1 antibody(1G3), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101113.10
Protein function: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair. [The UniProt Consortium]
| Schlagworte: | Anti-HAVCR, Anti-HAVCR-1, Anti-KIM-1, Anti-KIM1, Anti-TIM, Anti-TIM-1, Anti-TIM1, Anti-TIMD-1, Anti-TIMD1, Anti-TIM-1... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD205 antibody(1D4), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101114.10
Protein function: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B- lymphocytes. [The UniProt Consortium]
| Schlagworte: | Anti-LY75, Anti-CLEC13B, Anti-DEC-205, Anti-GP200-MR6, Anti-LY-75, Anti-CD205 antibody(1D4), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-ANPEP antibody(26H2), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101149.10
Protein function: Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and...
| Schlagworte: | Anti-APN, Anti-CD13, Anti-GP150, Anti-LAP1, Anti-P150, Anti-PEPN, Anti-ANPEP antibody(26H2), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD19 antibody(16B8), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101150.10
Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling pathways that lead...
| Schlagworte: | Anti-CD19, Anti-B4, Anti-CVID3, Anti-MGC12802, Anti-CD19 antibody(16B8), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-ADAMTS1 antibody(8A9), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101151.10
Protein function: Cleaves aggrecan, a cartilage proteoglycan, at the '1938- Glu-, -Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as...
| Schlagworte: | Anti-ADAM-TS 1, Anti-ADAM-TS1, Anti-ADAMTS-1, Anti-METH-1, Anti-ADAMTS1 antibody(8A9), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GPNMB antibody(11G4), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101152.10
Protein function: Could be a melanogenic enzyme. [The UniProt Consortium]
| Schlagworte: | Anti-HGFIN, Anti-NMB, Anti-PLCA3, Anti-GPNMB antibody(11G4), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-His Tag Antibody(DM1), Rabbit mAb
Artikelnummer: DIM-DME100001.10
| Schlagworte: | Anti-his tag, Anti-His Tag Antibody(DM1), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | broad |
ab 145,00 €
Anti-BCMA antibody(DM4), Rabbit mAb
Artikelnummer: DIM-DME100004.10
Protein function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [The UniProt Consortium]
| Schlagworte: | Anti-TNFRSF17, Anti-BCMA antibody(DM4), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-BCMA antibody(DM6), Rabbit mAb
Artikelnummer: DIM-DME100006.10
Protein function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [The UniProt Consortium]
| Schlagworte: | Anti-TNFRSF17, Anti-BCMA antibody(DM6), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-SIRPa(DM8) antibody, Rabbit mAb
Artikelnummer: DIM-DME100008.10
Protein function: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in...
| Schlagworte: | Anti-BIT, Anti-CD172a, Anti-MFR, Anti-MYD-1, Anti-P84, Anti-PTPNS1, Anti-SHPS-1, Anti-SHPS1, Anti-SIRP, Anti-SIRP-ALPHA-1,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €