Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
Mehr Informationen unter: www.dimabio.com
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-APP antibody(3D7), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101002.10
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis (PubMed:25122912). Involved in cell mobility and...
| Schlagworte: | Anti-AAA, Anti-ABETA, Anti-ABPP, Anti-AD1, Anti-APPI, Anti-CTFgamma, Anti-CVAP, Anti-PN-II, Anti-PN2, Anti-preA4, Anti-APP... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CCR5 antibody(4F6), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101003.10
Protein function: Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. [The UniProt...
| Schlagworte: | Anti-CC-CKR-5, Anti-CCCKR5, Anti-CCR-5, Anti-CD195, Anti-CKR-5, Anti-CKR5, Anti-CMKBR5, Anti-IDDM22, Anti-CCR5... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GPC1 antibody(1B8), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101004.10
Protein function: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination. May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan...
| Schlagworte: | Anti-Glypican 1, Anti-PC1, Anti-GPC1 antibody(1B8), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD6 antibody(1G6), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101005.10
Protein function: Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166 (PubMed:15048703, PubMed:15294938, PubMed:16352806, PubMed:16914752, PubMed:24945728, PubMed:24584089). Contributes to signaling cascades triggered by activation of the...
| Schlagworte: | Anti-TP120, Anti-CD6 antibody(1G6), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IL1A antibody(4G2), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101006.10
Protein function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to...
| Schlagworte: | Anti-IL-1 alpha, Anti-IL-1A, Anti-IL1, Anti-IL1-ALPHA, Anti-IL1F1, Anti-IL1A antibody(4G2), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD79B antibody(52A11), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101033.10
Protein function: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by...
| Schlagworte: | Anti-AGM6, Anti-B29, Anti-IGB, Anti-CD79B antibody(52A11), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-BTN3A2 antibody(3G2), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101034.10
Protein function: Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells. [The UniProt Consortium]
| Schlagworte: | Anti-BT3.2, Anti-BTF4, Anti-BTN3.2, Anti-CD277, Anti-BTN3A2 antibody(3G2), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CGRP antibody(7C1), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101035.10
Protein function: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. [The UniProt Consortium]
| Schlagworte: | Anti-CALC1, Anti-CALCA, Anti-CGRP-alpha, Anti-CGRP-I, Anti-CGRP1, Anti-CT, Anti-KC, Anti-PCT, Anti-CGRP antibody(7C1),... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-FGF19 antibody(6A5), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101036.10
Protein function: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. [The UniProt Consortium]
| Schlagworte: | Anti-FGF-19, Anti-UNQ334/PRO533, Anti-FGF19 antibody(6A5), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TNFRSF1B antibody(8C4), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101037.10
Protein function: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha....
| Schlagworte: | Anti-CD120b, Anti-p75, Anti-p75TNFR, Anti-TBPII, Anti-TNF-R-II, Anti-TNF-R75, Anti-TNFBR, Anti-TNFR1B, Anti-TNFR2,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD98 antibody(2H8), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101038.10
Protein function: Component of several heterodimeric amino acid transporter complexes (PubMed:11557028, PubMed:9829974, PubMed:9751058, PubMed:10391915, PubMed:10574970, PubMed:11311135). The precise substrate specificity depends on the other subunit in the heterodimer (PubMed:9829974, PubMed:9751058,...
| Schlagworte: | Anti-SLC3A2, Anti-F2, Anti-MDU1, Anti-4F2HC, Anti-4T2HC, Anti-NACAE, Anti-CD98HC, Anti-CD98 antibody(2H8), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CLEC4C antibody(12D6), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC101039.10
Protein function: Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PubMed:11748283, PubMed:21880719, PubMed:25995448). Specifically recognizes non-sialylated galactose- terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man...
| Schlagworte: | Anti-BDCA-2, Anti-CD303, Anti-CLEC4C antibody(12D6), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €