Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-LIV-1(ladiratuzumab biosimilar) mAb
Artikelnummer: DIM-BME100113.100
Protein function: May act as a zinc-influx transporter. [The UniProt Consortium]
| Schlagworte: | Anti-LIV1, Anti-SLC39A6, Anti-ZIP-6, Anti-LIV-1(ladiratuzumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL22(fezakinumab biosimilar) mAb
Artikelnummer: DIM-BME100114.100
Protein function: Cytokine that contributes to the inflammatory response in vivo. [The UniProt Consortium]
| Schlagworte: | Anti-IL-22, Anti-Cytokine Zcyto18, Anti-IL-TIF, Anti-IL22(fezakinumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CCR8(BMS 986340) mAb
Artikelnummer: DIM-BME100115.100
Protein function: Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. [The UniProt Consortium]
| Schlagworte: | Anti-CC-CKR-8, Anti-CCR-8, Anti-CDw198, Anti-CKRL1, Anti-CMKBR8, Anti-CMKBRL2, Anti-CY6, Anti-GPRCY6, Anti-TER1,... |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL1B(canakinumab biosimilar) mAb
Artikelnummer: DIM-BME100116.100
Protein function: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production....
| Schlagworte: | Anti-IL-1 beta, Anti-IL1F2, Anti-IL1B(canakinumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IFNAR1(anifrolumab biosimilar) mAb
Artikelnummer: DIM-BME100117.100
Protein function: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986)....
| Schlagworte: | Anti-IFN-R-1, Anti-CRF2-1, Anti-IFNAR, Anti-IFNAR1(anifrolumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-MST1R(narnatumab biosimilar) mAb
Artikelnummer: DIM-BME100118.100
Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its...
| Schlagworte: | Anti-CD136, Anti-CDw136, Anti-NPCA3, Anti-PTK8, Anti-RON, Anti-MST1R(narnatumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-NRP1(vesencumab biosimilar) mAb
Artikelnummer: DIM-BME100119.100
Protein function: Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins (PubMed:9288753, PubMed:9529250, PubMed:10688880)....
| Schlagworte: | Anti-Neuropilin-1, Anti-CD304, Anti-NRP1(vesencumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-C5AR1(avdoralimab biosimilar) mAb
Artikelnummer: DIM-BME100120.100
Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high- affinity site on the extracellular...
| Schlagworte: | Anti-C5a-R, Anti-C5aR, Anti-CD88, Anti-C5AR1(avdoralimab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL9(enokizumab biosimilar) mAb
Artikelnummer: DIM-BME100122.100
Protein function: Supports IL-2 independent and IL-4 independent growth of helper T-cells. [The UniProt Consortium]
| Schlagworte: | Anti-Interleukin-9, Anti-IL-9, Anti-Cytokine P40, Anti-T-cell growth factor P40, Anti-IL9(enokizumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD142(tisotumab biosimilar) mAb
Artikelnummer: DIM-BME100124.100
Protein function: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade....
| Schlagworte: | Anti-Tissue factor, Anti-TF, Anti-F3, Anti-Thromboplastin, Anti-Coagulation factor III, Anti-CD142(tisotumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CCL2(carlumab biosimilar) mAb
Artikelnummer: DIM-BME100125.100
Protein function: Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:9837883, PubMed:10587439, PubMed:10529171). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:9837883, PubMed:10587439). Exhibits a chemotactic...
| Schlagworte: | Anti-HC11, Anti-MCAF, Anti-MCP-1, Anti-CCL2(carlumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-SSTR2(tidutamab biosimilar) mAb
Artikelnummer: DIM-BME100127.100
Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by...
| Schlagworte: | Anti-SS-2-R, Anti-SS2-R, Anti-SS2R, Anti-SST2, Anti-SRIF-1, Anti-SSTR2(tidutamab biosimilar) mAb |
| Wirt: | Chimeric Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €