Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-MICA antibody(7F12), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100608.10
Protein function: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. [The UniProt Consortium]
| Schlagworte: | Anti-MIC-A, Anti-PERB11.1, Anti-MICA antibody(7F12), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CDH17 antibody(5F5), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100637.10
Protein function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and...
| Schlagworte: | Anti-CDH16, Anti-HPT-1, Anti-HPT1, Anti-CDH17 antibody(5F5), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CRTAM antibody(DMC673), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100673.10
Protein function: Mediates heterophilic cell-cell adhesion which regulates the activation, differentiation and tissue retention of various T-cell subsets. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and IFNG/interferon-gamma secretion by CD8+ T- cells in vitro as well as NK cell-mediated...
| Schlagworte: | Anti-CD355, Anti-CRTAM antibody(DMC673), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD74 antibody(DMC674), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100674.10
Protein function: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and...
| Schlagworte: | Anti-DHLAG, Anti-HLADG, Anti-Ia-GAMMA, Anti-II, Anti-p33, Anti-CD74 antibody(DMC674), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CDH6 antibody(DMC675), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100675.10
Protein function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. [The UniProt Consortium]
| Schlagworte: | Anti-CDH6, Anti-K-cadherin, Anti-CDH6 antibody(DMC675), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CXCR5 antibody(DMC679), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100679.10
Protein function: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell...
| Schlagworte: | Anti-Blr1, Anti-CXC-R5, Anti-CXCR-5, Anti-Gpcr6, Anti-MDR15, Anti-CXCR5 antibody(DMC679), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CXCR4 antibody(DMC680), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100680.10
Protein function: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation (PubMed:10452968, PubMed:28978524, PubMed:18799424, PubMed:24912431). Involved in the AKT signaling cascade (PubMed:24912431). Plays a role in...
| Schlagworte: | Anti-CD184, Anti-D2S201E, Anti-FB22, Anti-HM89, Anti-HSY3RR, Anti-LAP-3, Anti-LAP3, Anti-LCR1, Anti-LESTR, Anti-NPY3R,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CXCR2 antibody(DMC681), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100681.10
Protein function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also...
| Schlagworte: | Anti-CD182, Anti-CDw128b, Anti-CMKAR2, Anti-IL8R2, Anti-IL8RA, Anti-IL8RB, Anti-CXCR2 antibody(DMC681), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD166 antibody(DMC682), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100682.10
Protein function: Cell adhesion molecule that mediates both heterotypic cell- cell contacts via its interaction with CD6, as well as homotypic cell- cell contacts (PubMed:7760007, PubMed:15496415, PubMed:15048703, PubMed:16352806, PubMed:23169771, PubMed:24945728). Promotes T-cell activation and proliferation via...
| Schlagworte: | Anti-CD166, Anti-MEMD, Anti-CD166 antibody(DMC682), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TENM4 antibody(DMC683), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100683.10
Protein function: Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation and cellular process formation of oligodendrocytes and myelination of...
| Schlagworte: | Anti-Doc4, Anti-ETM5, Anti-ODZ4, Anti-ten-4, Anti-Ten-M4, Anti-TEN4, Anti-TNM4, Anti-TENM4 antibody(DMC683), IgG1 Chimeric... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CEACAM6 antibody(DMC685), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100685.10
Protein function: Cell surface glycoprotein that plays a role in cell adhesion and tumor progression (PubMed:2803308, PubMed:2022629, PubMed:1378450, PubMed:8776764, PubMed:11590190, PubMed:10910050, PubMed:14724575, PubMed:16204051). Intercellular adhesion occurs in a calcium- and fibronectin-independent manner...
| Schlagworte: | Anti-CD66c, Anti-CEAL, Anti-NCA, Anti-CEACAM6 antibody(DMC685), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-ALPP antibody(DMC686), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100686.10
| Schlagworte: | Anti-ALP, Anti-ALPI, Anti-IAP, Anti-PALP, Anti-PLAP, Anti-PLAP-1, Anti-ALPP antibody(DMC686), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €