Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-CRTAM antibody(DMC489), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100489.10
Protein function: Mediates heterophilic cell-cell adhesion which regulates the activation, differentiation and tissue retention of various T-cell subsets. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and IFNG/interferon-gamma secretion by CD8+ T- cells in vitro as well as NK cell-mediated...
| Schlagworte: | Anti-CD355, Anti-CRTAM antibody(DMC489), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GPR75 antibody(DMC492), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100492.10
Protein function: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a...
| Schlagworte: | Anti-Probable G-protein coupled receptor 75, Anti-GPR75 antibody(DMC492), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-MUC1 antibody(DMC493), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100493.10
Protein function: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. [The UniProt Consortium]
| Schlagworte: | Anti-ADMCKD, Anti-ADMCKD1, Anti-CA 15-3, Anti-CD227, Anti-EMA, Anti-H23AG, Anti-KL-6, Anti-MAM6, Anti-MCD, Anti-MCKD,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD32a antibody(DMC494), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100494.10
Protein function: Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. [The UniProt Consortium]
| Schlagworte: | Anti-CD32, Anti-CD32A, Anti-CDw32, Anti-FCG2, Anti-FcGR, Anti-FCGR2, Anti-FCGR2A1, Anti-IGFR2, Anti-CD32a... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-YAP1 antibody(DMC495), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100495.10
Protein function: Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis...
| Schlagworte: | Anti-COB1, Anti-YAP, Anti-YAP2, Anti-YAP65, Anti-YKI, Anti-YAP1 antibody(DMC495), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-LILRB2 antibody(DMC496), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100496.10
Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:11169396, PubMed:12853576, PubMed:16455647, PubMed:20448110, PubMed:27859042). Involved in the down-regulation of the immune response and the development of tolerance. Recognizes...
| Schlagworte: | Anti-LIR-2, Anti-ILT-4, Anti-MIR-10, Anti-CD85d, Anti-LILRB2 antibody(DMC496), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GPA33 antibody(DMC497), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100497.10
Protein function: May play a role in cell-cell recognition and signaling. [The UniProt Consortium]
| Schlagworte: | Anti-A33, Anti-GPA33 antibody(DMC497), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GDNF antibody(DMC498), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100498.10
Protein function: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. [The UniProt Consortium]
| Schlagworte: | Anti-ATF, Anti-ATF1, Anti-ATF2, Anti-HFB1-GDNF, Anti-HSCR3, Anti-GDNF antibody(DMC498), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CXCL1 antibody(DMC499), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100499.10
Protein function: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO- alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. [The UniProt Consortium]
| Schlagworte: | Anti-FSP, Anti-GRO1, Anti-GROa, Anti-MGSA, Anti-MGSA-a, Anti-NAP-3, Anti-SCYB1, Anti-CXCL1 antibody(DMC499), IgG1 Chimeric... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-HBEGF antibody(DMC500), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100500.10
Protein function: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial...
| Schlagworte: | Anti-DTR, Anti-DTS, Anti-DTSF, Anti-HEGFL, Anti-HBEGF antibody(DMC500), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GUCY2C antibody(6E3), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100508.10
Protein function: Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin. [The UniProt Consortium]
| Schlagworte: | Anti-DIAR6, Anti-GC-C, Anti-GUC2C, Anti-MECIL, Anti-MUCIL, Anti-STAR, Anti-GUCY2C antibody(6E3), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-FOLR1 antibody(18A3), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100585.10
Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation...
| Schlagworte: | Anti-FBP, Anti-FOLR, Anti-FRalpha, Anti-FOLR1 antibody(18A3), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €