Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-SIGLEC7 antibody(DMC475), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100475.10
Protein function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic...
| Schlagworte: | Anti-AIRM-1, Anti-AIRM1, Anti-CD328, Anti-CDw328, Anti-D-siglec, Anti-p75, Anti-p75:AIRM1, Anti-QA79, Anti-SIGLEC-7,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD164 antibody(DMC476), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100476.10
Protein function: Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May...
| Schlagworte: | Anti-LMOR, Anti-M-OR-1, Anti-MOP, Anti-MOR, Anti-MOR1, Anti-OPRM, Anti-CD164 antibody(DMC476), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CCR6 antibody(DMC477), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100477.10
Protein function: Receptor for the C-C type chemokine CCL20 (PubMed:9169459). Binds to CCL20 and subsequently transduces a signal by increasing the intracellular calcium ion levels (PubMed:20068036). Although CCL20 is its major ligand it can also act as a receptor for non-chemokine ligands such as beta-defensins...
| Schlagworte: | Anti-BN-1, Anti-C-C CKR-6, Anti-CC-CKR-6, Anti-CCR-6, Anti-CD196, Anti-CKR-L3, Anti-CKRL3, Anti-CMKBR6, Anti-DCR2,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GPR87 antibody(DMC478), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100478.10
Protein function: Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage. [The UniProt Consortium]
| Schlagworte: | Anti-FKSG78, Anti-GPR95, Anti-KPG_002, Anti-GPR87 antibody(DMC478), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-APCDD1 antibody(DMC479), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100479.10
Protein function: Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta- catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis. [The UniProt Consortium]
| Schlagworte: | Anti-B7323, Anti-DRAPC1, Anti-FP7019, Anti-HHS, Anti-HTS, Anti-HYPT1, Anti-APCDD1 antibody(DMC479), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-DDR1 antibody(DMC480), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100480.10
Protein function: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that...
| Schlagworte: | Anti-CAK, Anti-EDDR1, Anti-NEP, Anti-NTRK4, Anti-PTK3A, Anti-RTK6, Anti-TRKE, Anti-MCK-10, Anti-HGK2, Anti-CD167a,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-ADGRE1 antibody(DMC481), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100481.10
Protein function: Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. [The UniProt Consortium]
| Schlagworte: | Anti-EMR1, Anti-TM7LN3, Anti-ADGRE1 antibody(DMC481), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GPR77 antibody(DMC482), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100482.10
Protein function: Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways. [The UniProt Consortium]
| Schlagworte: | Anti-C5L2, Anti-GPF77, Anti-GPR77, Anti-GPR77 antibody(DMC482), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CHI3L1 antibody(DMC483), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100483.10
Protein function: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced...
| Schlagworte: | Anti-ASRT7, Anti-CGP-39, Anti-GP-39, Anti-GP39, Anti-HC-gp39, Anti-HCGP-3P, Anti-hCGP-39, Anti-YK-40, Anti-YKL-40,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CDH1 antibody(DMC484), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100484.10
Protein function: Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions,...
| Schlagworte: | Anti-Arc-1, Anti-BCDS1, Anti-CD324, Anti-CDHE, Anti-ECAD, Anti-LCAM, Anti-UVO, Anti-CDH1 antibody(DMC484), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD23 antibody(DMC486), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100486.10
Protein function: Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). [The UniProt Consortium]
| Schlagworte: | Anti-BLAST-2, Anti-CD23, Anti-CD23A, Anti-CLEC4J, Anti-FCE2, Anti-IGEBF, Anti-CD23 antibody(DMC486), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-LIV-1 antibody(DMC488), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100488.10
Protein function: May act as a zinc-influx transporter. [The UniProt Consortium]
| Schlagworte: | Anti-LIV1, Anti-SLC39A6, Anti-ZIP-6, Anti-LIV-1 antibody(DMC488), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €