Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-CD142 antibody(DMC463), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100463.10
Protein function: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade....
| Schlagworte: | Anti-TF, Anti-Coagulation factor III, Anti-F3, Anti-CD142 antibody(DMC463), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TNFSF15 antibody(DMC464), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100464.10
Protein function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. [The UniProt Consortium]
| Schlagworte: | Anti-TL1, Anti-VEGI, Anti-TNFSF15 antibody(DMC464), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CCR1 antibody(DMC465), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100465.10
Protein function: Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP- 1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP- 1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-CD191, Anti-CKR-1, Anti-CKR1, Anti-CMKBR1, Anti-HM145, Anti-MIP1aR, Anti-SCYAR1, Anti-CCR1 antibody(DMC465), IgG1... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CSPG4 antibody(DMC466), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100466.10
Protein function: Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells...
| Schlagworte: | Anti-CSPG4A, Anti-HMW-MAA, Anti-MCSP, Anti-MCSPG, Anti-MEL-CSPG, Anti-MSK16, Anti-NG2, Anti-CSPG4 antibody(DMC466), IgG1... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TGFBR2 antibody(DMC467), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100467.10
Protein function: Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus...
| Schlagworte: | Anti-AAT3, Anti-FAA3, Anti-LDS1B, Anti-LDS2, Anti-LDS2B, Anti-MFS2, Anti-RIIC, Anti-TAAD2, Anti-TBR-ii, Anti-TBRII,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CLEC1A antibody(DMC468), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100468.10
| Schlagworte: | Anti-CLEC-1, Anti-CLEC1, Anti-CLEC1A antibody(DMC468), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CLEC9A antibody(DMC469), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100469.10
Protein function: Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell...
| Schlagworte: | Anti-CD370, Anti-DNGR-1, Anti-DNGR1, Anti-UNQ9341, Anti-CLEC9A antibody(DMC469), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CXCR1 antibody(DMC470), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100470.10
Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high...
| Schlagworte: | Anti-C-C, Anti-C-C-CKR-1, Anti-CD128, Anti-CD181, Anti-CDw128a, Anti-CKR-1, Anti-CMKAR1, Anti-IL8R1, Anti-IL8RA,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IL22 antibody(DMC471), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100471.10
Protein function: Cytokine that contributes to the inflammatory response in vivo. [The UniProt Consortium]
| Schlagworte: | Anti-IL-22, Anti-IL-TIF, Anti-ZCYTO18, Anti-IL22 antibody(DMC471), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-EPHA4 antibody(DMC472), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100472.10
Protein function: Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway...
| Schlagworte: | Anti-EK8, Anti-HEK8, Anti-SEK, Anti-TYRO1, Anti-EPHA4 antibody(DMC472), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-EMCN antibody(DMC473), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100473.10
Protein function: Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. [The UniProt Consortium]
| Schlagworte: | Anti-Endomucin, Anti-MUC-14, Anti-EMCN antibody(DMC473), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GDF15 antibody(DMC474), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100474.10
Protein function: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL- expressing neurons localized in...
| Schlagworte: | Anti-GDF-15, Anti-MIC-1, Anti-MIC1, Anti-NAG-1, Anti-PDF, Anti-PLAB, Anti-PTGFB, Anti-GDF15 antibody(DMC474), IgG1... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €