Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-CD62L antibody(DMC439), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100439.10
Protein function: Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28489325, PubMed:28011641). Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and...
| Schlagworte: | Anti-CD62L, Anti-LAM1, Anti-LECAM1, Anti-LEU8, Anti-LNHR, Anti-LSEL, Anti-LYAM1, Anti-PLNHR, Anti-TQ1, Anti-CD62L... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-UPA antibody(DMC440), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100440.10
Protein function: May play an important role in maintaining normal growth homeostasis in epithelial cells. [The UniProt Consortium]
| Schlagworte: | Anti-ATF, Anti-BDPLT5, Anti-QPD, Anti-u-PA, Anti-UPA, Anti-URK, Anti-UPA antibody(DMC440), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD5L antibody(DMC441), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100441.10
Protein function: Secreted protein that acts as a key regulator of lipid synthesis: mainly expressed by macrophages in lymphoid and inflamed tissues and regulates mechanisms in inflammatory responses, such as infection or atherosclerosis. Able to inhibit lipid droplet size in adipocytes. Following incorporation into...
| Schlagworte: | Anti-AIM, Anti-API6, Anti-CT-2, Anti-hAIM, Anti-PRO229, Anti-SP-ALPHA, Anti-Spalpha, Anti-CD5L antibody(DMC441), IgG1... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CHODL antibody(DMC442), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100442.10
Protein function: May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance. [The UniProt Consortium]
| Schlagworte: | Anti-C21orf68, Anti-MT75, Anti-PRED12, Anti-CHODL antibody(DMC442), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CXCR7 antibody(DMC443), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100443.10
Protein function: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor...
| Schlagworte: | Anti-Atypical chemokine receptor 3, Anti-CXC-R7, Anti-CXCR-7, Anti-Chemokine orphan receptor 1, Anti-G-protein coupled... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-BST1 antibody(DMC444), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100444.10
Protein function: Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. [The UniProt Consortium]
| Schlagworte: | Anti-CD157, Anti-BST1 antibody(DMC444), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-SLAMF1 antibody(DMC445), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100445.10
Protein function: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and...
| Schlagworte: | Anti-SLAMF1, Anti-CD150, Anti-CDw150, Anti-SLAM, Anti-IPO-3, Anti-SLAMF1 antibody(DMC445), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD117 antibody(DMC446), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100446.10
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In...
| Schlagworte: | Anti-C-Kit, Anti-CD117, Anti-MASTC, Anti-PBT, Anti-SCFR, Anti-KIT, Anti-CD117 antibody(DMC446), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CCR2 antibody(DMC447), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100447.10
Protein function: Key functional receptor for CCL2 but can also bind CCL7 and CCL12 (PubMed:8146186, PubMed:8048929, PubMed:23408426). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium...
| Schlagworte: | Anti-CC-CKR-2, Anti-MCP-1-R, Anti-CD192, Anti-CCR2 antibody(DMC447), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-FGFR4 antibody(DMC460), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100460.10
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate...
| Schlagworte: | Anti-CD334, Anti-JTK2, Anti-TKF, Anti-FGFR4 antibody(DMC460), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CLU antibody(DMC461), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100461.10
Protein function: [Isoform 1]: Functions as extracellular chaperone that prevents aggregation of non native proteins (PubMed:11123922, PubMed:19535339). Prevents stress-induced aggregation of blood plasma proteins (PubMed:11123922, PubMed:12176985, PubMed:17260971, PubMed:19996109). Inhibits formation of amyloid...
| Schlagworte: | Anti-AAG4, Anti-APOJ, Anti-CLI, Anti-KUB1, Anti-MGC24903, Anti-SGP-2, Anti-SGP2, Anti-SP-40, Anti-TRPM-2, Anti-TRPM2,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-PRLR antibody(DMC462), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100462.10
Protein function: This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to...
| Schlagworte: | Anti-Prolactin receptor, Anti-PRL-R, Anti-PRLR antibody(DMC462), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €