Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-FLT3LG antibody(DMC421), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100421.10
Protein function: Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. [The UniProt Consortium]
| Schlagworte: | Anti-FLT3LG, Anti-FL, Anti-FLT3L, Anti-Flt3 ligand, Anti-FLT3LG antibody(DMC421), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IGFBP7 antibody(DMC422), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100422.10
Protein function: Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. [The UniProt Consortium]
| Schlagworte: | Anti-IBP-7, Anti-TAF, Anti-IGFBP-rP1, Anti-MAC25 protein, Anti-IGFBP7 antibody(DMC422), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD2 antibody(DMC423), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100423.10
Protein function: CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. [The UniProt Consortium]
| Schlagworte: | Anti-LFA-2, Anti-SRBC, Anti-T11, Anti-CD2 antibody(DMC423), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-EREG antibody(DMC424), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100424.10
Protein function: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation...
| Schlagworte: | Anti-Ep, Anti-EPR, Anti-ER, Anti-EREG antibody(DMC424), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD63 antibody(DMC425), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100425.10
Protein function: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin...
| Schlagworte: | Anti-CD63 antigen, Anti-Granulophysin, Anti-LAMP-3, Anti-Limp1, Anti-Melanoma-associated antigen ME491, Anti-OMA81H,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TSLP antibody(DMC426), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100426.10
Protein function: [Isoform 1]: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. [The UniProt Consortium]
| Schlagworte: | Anti-TSLP, Anti-TSLP antibody(DMC426), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GP6 antibody(DMC427), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100427.10
Protein function: Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the...
| Schlagworte: | Anti-BDPLT11, Anti-GPIV, Anti-GPVI, Anti-GP6 antibody(DMC427), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-SSTR2 antibody(DMC428), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100428.10
Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by...
| Schlagworte: | Anti-SRIF-1, Anti-SS2R, Anti-SSTR2 antibody(DMC428), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD81 antibody(DMC429), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100429.10
Protein function: Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells (PubMed:20237408,...
| Schlagworte: | Anti-CVID6, Anti-S5.7, Anti-TAPA1, Anti-TSPAN28, Anti-CD81 antibody(DMC429), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD83 antibody(DMC436), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100436.10
Protein function: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation. [The UniProt Consortium]
| Schlagworte: | Anti-BL11, Anti-HB15, Anti-CD83 antibody(DMC436), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-M-CSF antibody(DMC437), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100437.10
Protein function: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in...
| Schlagworte: | Anti-CSF-1, Anti-MCSF, Anti-M-CSF antibody(DMC437), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-Nectin4 antibody(DMC438), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100438.10
Protein function: Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. [The UniProt Consortium]
| Schlagworte: | Anti-EDSS1, Anti-LNIR, Anti-nectin-4, Anti-PRR4, Anti-PVRL4, Anti-Nectin4 antibody(DMC438), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €