Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-GPC3 antibody(DMC371), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100371.10
Protein function: Cell surface proteoglycan that bears heparan sulfate (PubMed:14610063). Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH...
| Schlagworte: | Anti-DGSX, Anti-GTR2-2, Anti-MXR7, Anti-OCI-5, Anti-SDYS, Anti-SGB, Anti-SGBS, Anti-SGBS1, Anti-GPC3 antibody(DMC371),... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CSF1R antibody(9A5), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100382.10
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
| Schlagworte: | Anti-CSF1R, Anti-C-FMS, Anti-CD115, Anti-CSFR, Anti-FIM2, Anti-FMS, Anti-M-CSFR, Anti-CSF1R antibody(9A5), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GUCY2C antibody(DMC387), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100387.10
Protein function: Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin. [The UniProt Consortium]
| Schlagworte: | Anti-DIAR6, Anti-GC-C, Anti-GUC2C, Anti-MECIL, Anti-MUCIL, Anti-STAR, Anti-GUCY2C antibody(DMC387), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-EDA antibody(DMC388), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100388.10
Protein function: Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R (PubMed:8696334, PubMed:11039935, PubMed:27144394). May also play a role in cell adhesion. [The UniProt...
| Schlagworte: | Anti-ED1, Anti-EDA2, Anti-EDA antibody(DMC388), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-VWF antibody(DMC389), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100389.10
Protein function: Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it...
| Schlagworte: | Anti-F8VWF, Anti-VWD, Anti-VWF antibody(DMC389), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-FOLR2 antibody(DMC390), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100390.10
Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation...
| Schlagworte: | Anti-BETA-HFR, Anti-FBP, Anti-FBP:PL-1, Anti-FOLR1, Anti-FR-BETA, Anti-FR-P3, Anti-FRbeta, Anti-FOLR2 antibody(DMC390),... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-FOLR1 antibody(DMC391), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100391.10
Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation...
| Schlagworte: | Anti-FBP, Anti-FOLR, Anti-FRalpha, Anti-FOLR1 antibody(DMC391), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-B4GALT1 antibody(DMC392), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100392.10
Protein function: [Beta-1,4-galactosyltransferase 1]: The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. [The...
| Schlagworte: | Anti-GGTB2, Anti-Beta4Gal-T1, Anti-b4Gal-T1, Anti-Nal synthase, Anti-B4GALT1 antibody(DMC392), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IL5RA antibody(DMC393), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100393.10
Protein function: This is the receptor for interleukin-5. The alpha chain binds to IL5. [The UniProt Consortium]
| Schlagworte: | Anti-IL5Ra, Anti-CD125, Anti-IL-5 R alpha, Anti-IL5RA antibody(DMC393), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CLEC2D antibody(DMC394), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100394.10
Protein function: Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:20843815, PubMed:16339513). Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656). Inhibits bone resorption (PubMed:14753741). Modulates the release of interferon-gamma (PubMed:15104121)....
| Schlagworte: | Anti-C-type lectin domain family 2 member D, Anti-Lectin-like NK cell receptor, Anti-LLT-1, Anti-Osteoclast inhibitory... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IL-6 antibody(DMC419), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100419.10
Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and...
| Schlagworte: | Anti-IL6, Anti-Interleukin-6, Anti-BSF2, Anti-HSF, Anti-IFNB2, Anti-IL-6 antibody(DMC419), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-PMEL antibody(DMC420), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100420.10
Protein function: Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the...
| Schlagworte: | Anti-D12S53E, Anti-gp100, Anti-ME20, Anti-ME20-M, Anti-ME20M, Anti-P1, Anti-P100, Anti-PMEL17, Anti-SI, Anti-SIL,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €