Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-IL17A (vunakizumab biosimilar) mAb, biotinylated
Artikelnummer: DIM-BME100732B.100
Research use only. Protein function: Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (PubMed:24120361). Signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with...
| Schlagworte: | SHR 1314,SHR-1314,SHR1314, Anti-IL-17, Anti-CTLA8, Anti-IL17A, Anti-CTLA-8, Anti-IL-17A, Anti-Interleukin-17A,... |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-PACR (zelminemab biosimilar) mAb
Artikelnummer: DIM-BME100737.100
Research use only. Protein function: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role...
| Schlagworte: | AMG-301,AMG301,AMG 301, Anti-PACAP-R1, Anti-PACAP-R-1, Anti-ADCYAP1R1, Anti-PACAP type I receptor, Anti-Pituitary... |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CLDN6, clone 402C8, IgG1 Chimeric mAb, biotinylated
Artikelnummer: DIM-DMC101199B.10
Purified from cell culture supernatant by affinity chromatography. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular...
| Schlagworte: | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous... |
| Anwendung: | FC |
| Wirt: | Rabbit/Human |
| Spezies-Reaktivität: | human |
ab 203,00 €
Anti-CLDN6, clone 407C3, IgG1 Chimeric mAb, biotinylated
Artikelnummer: DIM-DMC101200B.10
Purified from cell culture supernatant by affinity chromatography. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular...
| Schlagworte: | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous... |
| Anwendung: | FC |
| Wirt: | Rabbit/Human |
| Spezies-Reaktivität: | human |
ab 203,00 €
Anti-CLDN6, clone 407H9, IgG1 Chimeric mAb, biotinylated
Artikelnummer: DIM-DMC101201B.10
Purified from cell culture supernatant by affinity chromatography. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular...
| Schlagworte: | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous... |
| Anwendung: | FC |
| Wirt: | Rabbit/Human |
| Spezies-Reaktivität: | human |
ab 203,00 €
Anti-IFNG, clone 1A2, IgG1 Chimeric mAb, biotinylated
Artikelnummer: DIM-DMC101223B.10
Purified from cell culture supernatant by affinity chromatography. IFNgamma is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II...
| Schlagworte: | IFNgamma is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally... |
| Anwendung: | ELISA |
| Wirt: | Rabbit/Human |
| Spezies-Reaktivität: | human |
ab 203,00 €
Anti-CD72, clone 1E9, IgG1 Chimeric mAb, biotinylated
Artikelnummer: DIM-DMC101224B.10
Purified from cell culture supernatant by affinity chromatography. Plays a role in B-cell proliferation and differentiation.[UniProtKB/Swiss-Prot Function]. Protein function: Plays a role in B-cell proliferation and differentiation. [The UniProt Consortium]
| Schlagworte: | Plays a role in B-cell proliferation and differentiation.[UniProtKB/Swiss-Prot Function], Anti-CD72, Anti-Lyb-2,... |
| Anwendung: | FC |
| Wirt: | Rabbit/Human |
| Spezies-Reaktivität: | human |
ab 203,00 €
Anti-SEMA4D, clone 11G2, IgG1 Chimeric mAb, biotinylated
Artikelnummer: DIM-DMC101226B.10
Purified from cell culture supernatant by affinity chromatography. Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed:20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner...
| Schlagworte: | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed:20877282).... |
| Anwendung: | FC |
| Wirt: | Rabbit/Human |
| Spezies-Reaktivität: | human |
ab 203,00 €
Anti-TSHR, clone 1C8, IgG1 Chimeric mAb, biotinylated
Artikelnummer: DIM-DMC101228B.10
Purified from cell culture supernatant by affinity chromatography. The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene...
| Schlagworte: | The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded... |
| Anwendung: | FC |
| Wirt: | Rabbit/Human |
| Spezies-Reaktivität: | human |
ab 203,00 €
Anti-CD20, clone 1F2, IgG1 Chimeric mAb, biotinylated
Artikelnummer: DIM-DMC101229B.10
Purified from cell culture supernatant by affinity chromatography. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among...
| Schlagworte: | This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are... |
| Anwendung: | FC |
| Wirt: | Rabbit/Human |
| Spezies-Reaktivität: | human |
ab 203,00 €
Anti-TweakR, clone 58A12, IgG1 Chimeric mAb, biotinylated
Artikelnummer: DIM-DMC101230B.10
Purified from cell culture supernatant by affinity chromatography. TNFRSF12A (TNF Receptor Superfamily Member 12A) is a Protein Coding gene. Diseases associated with TNFRSF12A include Multiple Sclerosis and Stroke,Ischemic. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of...
| Schlagworte: | TNFRSF12A (TNF Receptor Superfamily Member 12A) is a Protein Coding gene. Diseases associated with TNFRSF12A include... |
| Anwendung: | FC |
| Wirt: | Rabbit/Human |
| Spezies-Reaktivität: | human |
ab 203,00 €
Anti-FGF21, clone 19H8, IgG1 Chimeric mAb, biotinylated
Artikelnummer: DIM-DMC101231B.10
Purified from cell culture supernatant by affinity chromatography. This gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that...
| Schlagworte: | This gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and... |
| Anwendung: | ELISA |
| Wirt: | Rabbit/Human |
| Spezies-Reaktivität: | human |
ab 203,00 €