Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-GDF8 (trevogrumab biosimilar) mAb, biotinylated
Artikelnummer: DIM-BME100708B.100
Research use only. Protein function: Acts specifically as a negative regulator of skeletal muscle growth. [The UniProt Consortium]
| Schlagworte: | REGN-1033,REGN1033,REGN 1033,SAR-391786,SAR 391786,SAR391786, Anti-MSTN, Anti-GDF8, Anti-GDF-8, Anti-Myostatin,... |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-LAG3 (tuparstobart biosimilar) mAb, biotinylated
Artikelnummer: DIM-BME100710B.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Schlagworte: | Incagn-02385,Incagn02385,Incagn 02385, Anti-FDC |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD20 (ublituximab biosimilar) mAb, biotinylated
Artikelnummer: DIM-BME100713B.100
Research use only. Protein function: B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC)...
| Schlagworte: | BRIUMV,EMAB-6,EMAB6,EMAB 6,EMAB-603,EMAB603,EMAB 603,LFB-R603,LFB R603,TG-1101,TG1101,RG 1101,TG-20,TG20,TG... |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD200R1 (ucenprubart biosimilar) mAb
Artikelnummer: DIM-BME100714.100
Research use only. Protein function: Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14...
| Schlagworte: | LY3454738,LY-3454738,LY 3454738, Anti-CD200R, Anti-CD200R1, Anti-Cell surface glycoprotein OX2 receptor 1, Anti-CD200 cell... |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-4-1BB (urelumab biosimilar) mAb
Artikelnummer: DIM-BME100717.100
Research use only. Protein function: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. [The UniProt Consortium]
| Schlagworte: | BMS-663513,BMS663513,BMS 663513,BMS-66513,BMS66513,BMS 66513,ONO-4481,ONO4481,ONO 4481, Anti-CD137, Anti-CDw137,... |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-APP (usilnetug biosimilar) mAb, biotinylated
Artikelnummer: DIM-BME100718B.100
Research use only. Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis (PubMed:25122912). Involved in cell...
| Schlagworte: | PR-1905069,PR 1905069,PR1905069, Anti-A4 |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-BTLA (venanprubart biosimilar) mAb, biotinylated
Artikelnummer: DIM-BME100722B.100
Research use only. Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14...
| Schlagworte: | LY-3361237,LY3361237,LY 3361237, Anti-CD272, Anti-B- and T-lymphocyte attenuator, Anti-B- and T-lymphocyte-associated protein |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IL1A (vilamakitug biosimilar) mAb, biotinylated
Artikelnummer: DIM-BME100725B.100
Research use only. Protein function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and...
| Schlagworte: | Natrunix,XB-2001,XB2001,XB 2001, Anti-IL1A, Anti-IL1F1, Anti-IL-1 alpha, Anti-Hematopoietin-1, Anti-Interleukin-1 alpha |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CTLA-4 (vilastobart biosimilar) mAb
Artikelnummer: DIM-BME100726.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Schlagworte: | XTX-101,XTX 101,XTX101, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic... |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-C5 (vilobelimab biosimilar) mAb, biotinylated
Artikelnummer: DIM-BME100727B.100
Research use only. Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt...
| Schlagworte: | CaC-P29,Gohibic,IFX-1,IFX 1,IFX1, Anti-C5, Anti-CPAMD4 |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-GDF15 (visugromab biosimilar) mAb
Artikelnummer: DIM-BME100728.100
Research use only. Protein function: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL- expressing...
| Schlagworte: | CTL-002,CTL002,CTL 002, Anti-NRG-1, Anti-MIC-1, Anti-NAG-1, Anti-GDF-15, Anti-Placental TGF-beta, Anti-NSAID-regulated... |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-NPR1 (vixticibart biosimilar) mAb
Artikelnummer: DIM-BME100729.100
Research use only. Protein function: Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. [The UniProt Consortium]
| Schlagworte: | TBC, Anti-NPR1, Anti-GC-A, Anti-ANPRA, Anti-ANP-A, Anti-NPR-A, Anti-ANPR-A, EC=4.6.1.2, Anti-Guanylate cyclase A,... |
| Spezies-Reaktivität: | human |
ab 120,00 €