Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human IL2RA Protein, His Tag
Artikelnummer: DIM-PME100098.10
Recombinant human IL2RA Protein with C-terminal 6×His tag. IL2RA(Glu22-Cys213) 6×His tag, Protein function: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive...
| Schlagworte: | IL2RA, CD25, p55, IL2-RA, IL-2-RA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 22.6 kD |
ab 120,00 €
Human EGFR Protein, His Tag
Artikelnummer: DIM-PME100099.10
Recombinant human EGFR Protein with C-terminal 6×His tag. EGFR(Leu25-Ser645) 6×His tag, Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725,...
| Schlagworte: | EGFR, ERBB, ERBB1, HER1, PIG61, mENA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 69.4 kD |
ab 120,00 €
Human TNFSF11 Protein, hFc Tag
Artikelnummer: DIM-PME100100.10
Recombinant human TNFSF11 Protein with N-terminal Human Fc tag. hFc(Glu99-Ala330) TNFSF11(Ile140-Asp317), Protein function: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation....
| Schlagworte: | CD254, hRANKL2, ODF, OPGL, OPTB2, RANKL, sOdf, TNLG6B, TRANCE |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 48.4 kD |
ab 124,00 €
Human CD46 Protein, His Tag
Artikelnummer: DIM-PME100102.10
Recombinant human CD46 Protein with C-terminal 6×His tag. CD46(Cys35-Tyr328) 6×His tag, Protein function: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of...
| Schlagworte: | CD46, AHUS2, MCP, MIC10, TLX, TRA2.10 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 33.5 kD |
ab 105,00 €
Human TGFBR1 Protein, N-hFc Tag
Artikelnummer: DIM-PME100103.10
Recombinant human TGFBR1 Protein with N-terminal Human Fc tag. hFc(Glu99-Ala330) TGFBR1(Leu34-Leu126), Protein function: Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3....
| Schlagworte: | AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, tbetaR-I, TBR-i, TBRI, TGFR-1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 36.3 kD |
ab 105,00 €
Anti-VEGFA antibody(DMC276), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100276.10
Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin....
| Schlagworte: | Anti-MVCD1, Anti-VEGF, Anti-VPF, Anti-VEGFA antibody(DMC276), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-LGALS1 antibody(DMC277), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100277.10
Protein function: Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. [The...
| Schlagworte: | Anti-GAL1, Anti-GBP, Anti-LGALS1 antibody(DMC277), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-JAM-A antibody(DMC278), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100278.10
Protein function: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role...
| Schlagworte: | Anti-CD321, Anti-JAM, Anti-JAM1, Anti-JAMA, Anti-JCAM, Anti-KAT, Anti-PAM-1, Anti-JAM-A antibody(DMC278), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-Galectin 9 antibody(DMC279), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100279.10
Protein function: Binds galactosides (PubMed:18005988). Has high affinity for the Forssman pentasaccharide (PubMed:18005988). Ligand for HAVCR2/TIM3 (PubMed:16286920). Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (PubMed:16286920). Also stimulates bactericidal activity in infected macrophages by...
| Schlagworte: | Anti-Galectin-9, Anti-LGALS9, Anti-Ecalectin, Anti-Gal-9, Anti-Galectin 9 antibody(DMC279), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD21 antibody(DMC280), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100280.10
Protein function: Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU (PubMed:7753047). Participates in B lymphocytes activation (PubMed:7753047). [The UniProt Consortium]
| Schlagworte: | Anti-C3DR, Anti-CD21, Anti-CR, Anti-CVID7, Anti-SLEB9, Anti-CD21 antibody(DMC280), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-AFP antibody(DMC281), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100281.10
Protein function: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. [The UniProt Consortium]
| Schlagworte: | Anti-AFPD, Anti-FETA, Anti-HPAFP, Anti-AFP antibody(DMC281), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IL11RA antibody(DMC282), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100282.10
Protein function: Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal...
| Schlagworte: | Anti-IL-11 R alpha, Anti-IL-11 RA, Anti-IL11RA, Anti-Interleukin-11 receptor subunit alpha, Anti-IL-11 receptor subunit... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €