Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human FCGR3A Protein (F176V), His Tag
Artikelnummer: DIM-PME100069.10
Recombinant human FCGR3A protein(F176V) with C-terminal 6×His tag. FCGR3A(Gly17-Gly206)(F176V) 6×His tag, Protein function: Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses,...
| Schlagworte: | FCGR3A, CD16A, FCG3, FCGR3, IGFR3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 22.3 kD |
ab 105,00 €
Human AXL Protein, His Tag
Artikelnummer: DIM-PME100070.10
Recombinant human AXL protein with C-terminal 6×His tag. AXL(Ala26-Pro449) 6×His tag, Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival,...
| Schlagworte: | AXL, UFO |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 46.6 kD |
ab 120,00 €
Human CEACAM5 Protein, His Tag
Artikelnummer: DIM-PME100071.10
Recombinant human CEACAM5 protein with C-terminal 6×His tag. CEACAM5(Lys35-Ala685) 6×His tag, Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell...
| Schlagworte: | CEACAM-5, CD66e, CEA, Meconium antigen 100 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 72.2 kD |
ab 120,00 €
Human ACE2 Protein, mFc Tag
Artikelnummer: DIM-PME100072.10
Recombinant human ACE2 protein with C-terminal mouse Fc tag. ACE2(Gln18-Ser740) mFc(Pro99-Lys330), Protein function: Essential counter-regulatory carboxypeptidase of the renin- angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis...
| Schlagworte: | ACE-2, ACEH, ACE2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 109.7 kD |
ab 114,00 €
Human ACE2 Protein, hFc Tag
Artikelnummer: DIM-PME100073.10
Recombinant human ACE2 protein with C-terminal human Fc tag. ACE2(Gln18-Ser740) hFc(Glu99-Ala330), Protein function: Essential counter-regulatory carboxypeptidase of the renin- angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis...
| Schlagworte: | ACE-2, ACEH, ACE2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 109.7 kD |
ab 120,00 €
Human IL2RB Protein, His Tag
Artikelnummer: DIM-PME100074.10
Recombinant human IL2RB protein with C-terminal 6×His tag. IL2RB(Ala27-Asp239) 6×His tag, Protein function: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of...
| Schlagworte: | IL2RB, RP5-1170K4.6, CD122, P70-75 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 25.4 kD |
ab 120,00 €
Human AFP Protein, hFc Tag
Artikelnummer: DIM-PME100075.10
Recombinant human AFP protein with C-terminal human Fc tag. AFP(Arg19-Val609) hFc(Glu99-Ala330), Protein function: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. [The UniProt...
| Schlagworte: | AFPD, FETA, HPAFP |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 92.6 kD |
ab 124,00 €
Human TNFa Protein, His Tag
Artikelnummer: DIM-PME100076.10
Recombinant human TNFa protein with C-terminal 6×His tag. TNFalpha(Arg78-Leu233) 6×His tag, Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by...
| Schlagworte: | DIF, TNF-alpha, TNFA, TNFSF2, cachexin, cachectin, TNFalpha |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 18.1 kD |
ab 133,00 €
Human NKG2D Protein, mFc Tag
Artikelnummer: DIM-PME100079.10
Recombinant human NKG2D protein with N-terminal mouse Fc. mFc(Pro99-Lys330) NKG2D(Ile73-Val216), Protein function: Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and...
| Schlagworte: | NKG2D, CD314, KLRK1, NK cell receptor D |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 42.8 kD |
ab 120,00 €
Human NKp30 Protein, hFc Tag
Artikelnummer: DIM-PME100081.10
Recombinant human NKp30 protein with C-terminal human Fc. NKp30(Leu19-Gly135) hFc(Glu99-Ala330), Protein function: Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing...
| Schlagworte: | NCR3, CD337, NKp30, 1C7, LY117, MALS |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.0 kD |
ab 119,00 €
Human TNFRSF1B Protein, hFc Tag
Artikelnummer: DIM-PME100082.10
Recombinant Human TNFRSF1B Protein with C-terminal human Fc tag. TNFRSF1B(Leu23-Asp257) hFc(Glu99-Ala330), Protein function: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors...
| Schlagworte: | CD120b, p75, p75TNFR, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 51.3 kD |
ab 102,00 €
Human CD114 Protein, His Tag
Artikelnummer: DIM-PME100083.10
Recombinant human CD114 protein with C-terminal 6×His tag. CD114(Glu25-Glu622) 6×His tag, Protein function: Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic...
| Schlagworte: | CSF3R, CD114, GCSFR |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 67.5 kD |
ab 124,00 €