Produkte von DIMA Biotech

DIMA

DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her. 

Mehr Informationen unter: www.dimabio.com

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Human CD30 Ligand Protein, mFc-His Tag
Human CD30 Ligand Protein, mFc-His Tag

Artikelnummer: DIM-PME100041.10

Recombinant human CD30 Ligand Protein with N-terminal mouse Fc and C-terminal 6×His tag. mFc(Pro99-Lys330) CD30 Ligand(Gln63-Asp234) 6×His, Protein function: Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells. [The UniProt Consortium]
Schlagworte: CD30-L, CD153, TNFSF8, CD30L, CD30LG, CD153 antigen, CD30 antigen ligand, CD30 Ligand
Exprimiert in: Human cells
Ursprungsart: human
MW: 48.0 kD
ab 120,00 €
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Human CD70 Protein, mFc-His Tag
Human CD70 Protein, mFc-His Tag

Artikelnummer: DIM-PME100042.10

Recombinant human CD70 protein with N-terminal mouse Fc and C-terminal 6×His tag. mFc(Pro99-Lys330) CD70(Gln39-Pro193) 6×His, Protein function: Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral...
Schlagworte: CD70, CD27LG, TNFSF7, TNFSF7G, CD27L
Exprimiert in: Human cells
Ursprungsart: human
MW: 45.6 kD
ab 140,00 €
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Human BAFF Protein, hFc Tag
Human BAFF Protein, hFc Tag

Artikelnummer: DIM-PME100043.10

Recombinant Human BAFF protein with N-terminal human Fc. hFc(Glu99-Ala330) BAFF(Ala134-Leu285), Protein function: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T- cell...
Schlagworte: TNFSF13B, BAFF, BLYS, CD257, DTL, TALL1, THANK, TNFSF20, ZTNF4, TALL-1
Exprimiert in: Human cells
Ursprungsart: human
MW: 43.2 kD
ab 140,00 €
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Human BAFF-R Protein, mFc Tag
Human BAFF-R Protein, mFc Tag

Artikelnummer: DIM-PME100044.10

Recombinant Human BAFF-R protein with C-terminal mouse Fc. BAFF-R(Ser7-Ala71) mFc(Pro99-Lys330), Protein function: B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. [The UniProt Consortium]
Schlagworte: BAFFR, TNFRSF13C, BAFF-R, BROMIX, CD268, CVID4, prolixin
Exprimiert in: Human cells
Ursprungsart: human
MW: 33.6 kD
ab 120,00 €
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Human EPHA3 Protein, mFc-His Tag
Human EPHA3 Protein, mFc-His Tag

Artikelnummer: DIM-PME100045.10

Recombinant human EPHA3 protein with C-terminal mouse Fc and 6×His tag. EPHA3(Glu21-Gln541) mFc(Pro99-Lys330) 6×His tag, Protein function: Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into...
Schlagworte: TYRO4, HEK4, ETK1, ETK, EK4, HEK
Exprimiert in: Human cells
Ursprungsart: human
MW: 85.9 kD
ab 120,00 €
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Human CD20 Protein, hFc Tag
Human CD20 Protein, hFc Tag

Artikelnummer: DIM-PME100046.10

Recombinant Human CD20 protein with N-terminal human Fc. hFc(Glu99-Ala330) CD20(Lys142-Ser188), Protein function: B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015,...
Schlagworte: B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7
Exprimiert in: Human cells
Ursprungsart: human
MW: 31.6 kD
ab 114,00 €
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Human B7-1 Protein, mFc-His Tag
Human B7-1 Protein, mFc-His Tag

Artikelnummer: DIM-PME100047.10

Recombinant Human B7-1 Protein with C-terminal Mouse Fc and 6×His tag. B7-1(Val35-Asn242) mFc(Pro99-Lys330) 6×His tag, Protein function: Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has...
Schlagworte: CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7
Exprimiert in: Human cells
Ursprungsart: human
MW: 50.9 kD
ab 140,00 €
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Human BTLA Protein, mFc-His Tag
Human BTLA Protein, mFc-His Tag

Artikelnummer: DIM-PME100048.10

Recombinant human BTLA protein with C-terminal mouse Fc and 6×His tag. BTLA(Lys31-Ser150) mFc(Pro99-Lys330) 6×His tag, Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026,...
Schlagworte: BTLA, CD272
Exprimiert in: Human cells
Ursprungsart: human
MW: 41.3 kD
ab 140,00 €
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Human LIGHT Protein, hFc Tag
Human LIGHT Protein, hFc Tag

Artikelnummer: DIM-PME100049.10

Recombinant Human LIGHT protein with N-terminal human Fc. hFc(Glu99-Ala330) LIGHT(Leu83-Val240), Protein function: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM (PubMed:9462508, PubMed:10754304). Upon binding to TNFRSF14/HVEM,...
Schlagworte: TNFSF14, CD258, HVEML, LIGHT, LTg
Exprimiert in: Human cells
Ursprungsart: human
MW: 43.4 kD
ab 124,00 €
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Human DNAM-1 Protein, mFc-His Tag
Human DNAM-1 Protein, mFc-His Tag

Artikelnummer: DIM-PME100050.10

Recombinant human DNAM-1 protein with C-terminal mouse Fc and 6×His tag. DNAM-1(Glu19-Asn247) mFc(Pro99-Lys330) 6×His tag, Protein function: Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T- lymphocyte (CTL) and NK cell (PubMed:8673704). Cell...
Schlagworte: DNAM1, CD226, PTA1
Exprimiert in: Human cells
Ursprungsart: human
MW: 53.5 kD
ab 120,00 €
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Human B7-H4 Protein, hFc Tag
Human B7-H4 Protein, hFc Tag

Artikelnummer: DIM-PME100053.10

Recombinant Human B7-H4 protein with C-terminal human Fc. B7-H4 (Phe29-Ala258) hFc(Glu99-Ala330), Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor...
Schlagworte: B7-H4, B7h.5, B7H4, B7S1, B7X, PRO1291, VCTN1
Exprimiert in: Human cells
Ursprungsart: human
MW: 51.4 kD
ab 114,00 €
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Human 4-1BB Ligand Protein, mFc-His Tag
Human 4-1BB Ligand Protein, mFc-His Tag

Artikelnummer: DIM-PME100054.10

Recombinant human 4-1BB Ligand Protein with N-terminal mouse Fc and C-terminal 6×His tag. mFc(Pro99-Lys330) 4-1BB Ligand(Pro52-Glu254) 6×His, Protein function: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation- induced cell death (AICD)....
Schlagworte: 4-1BB Ligand, TNFSF9, CD137L
Exprimiert in: Human cells
Ursprungsart: human
MW: 49.8 kD
ab 124,00 €
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