Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human CD155 Protein, mFc-His tag
Artikelnummer: DIM-PME100027.10
Recombinant human CD155 protein with C-terminal mouse Fc and 6×His tag. CD155(Trp21-Asn343) mFc(Pro99-Lys330) 6×His tag, Protein function: Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact...
| Schlagworte: | PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 62.2 kD |
ab 114,00 €
Human CD96 Protein, mFc-His tag
Artikelnummer: DIM-PME100028.10
Recombinant human CD96 protein with C-terminal mouse Fc and 6×His tag. CD96(Val22-Asn487) mFc(Pro99-Lys330) 6×His tag, Protein function: May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present...
| Schlagworte: | TACTILE |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 78.9 kD |
ab 120,00 €
Human B7-H2 Protein, mFc-His Tag
Artikelnummer: DIM-PME100029.10
Recombinant human B7-H2 protein with C-terminal mouse Fc and 6×His tag. B7H2(Asp19-Thr256) mFc(Pro99-Lys330) 6×His tag, Protein function: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and...
| Schlagworte: | ICOSLG, B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, LICOS, ICOS ligand |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 53.9 kD |
ab 124,00 €
Human TIM3 Protein, mFc-His Tag
Artikelnummer: DIM-PME100030.10
Recombinant human TIM3 protein with C-terminal mouse Fc and 6×His tag. TIM3(Ser22-Gly202) mFc(Pro99-Lys330) 6×His tag, Protein function: Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest...
| Schlagworte: | HAVCR2, TIM3, TIMD3, FLJ14428, KIM3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 47.5 kD |
ab 124,00 €
Human Mesothelin (296-580) Protein, mFc-His Tag
Artikelnummer: DIM-PME100031.10
Recombinant human Mesothelin(296-580) protein with C-terminal mouse Fc and 6×His tag. Mesothelin(Glu296-Gly580) mFc(Pro99-Lys330) 6×His tag, Protein function: Membrane-anchored forms may play a role in cellular adhesion. [The UniProt Consortium]
| Schlagworte: | MSLN, Mesothelin, MPF |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 59.3 kD |
ab 120,00 €
Human IL6 Protein, mFc-His Tag
Artikelnummer: DIM-PME100032.10
Recombinant human IL6 protein with C-terminal mouse Fc and 6×His tag. IL6(Val30-Met212) mFc(Pro99-Lys330) 6×His tag, Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130...
| Schlagworte: | IL6, Interleukin-6, BSF2, HSF, IFNB2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 47.9 kD |
ab 140,00 €
Human FLT3 Ligand Protein, mFc-His Tag
Artikelnummer: DIM-PME100033.10
Recombinant human FLT3 Ligand protein with C-terminal mouse Fc and 6×His tag. FLT3 Ligand(Thr27-Pro184) mFc(Pro99-Lys330) 6×His tag, Protein function: Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. [The...
| Schlagworte: | FLT3LG, FL, FLT3L, Flt3 ligand |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 45.6 kD |
ab 124,00 €
Human B7-2 Protein, mFc-His Tag
Artikelnummer: DIM-PME100034.10
Recombinant human B7-2 protein with C-terminal mouse Fc and 6×His tag. B7-2(Leu26-Pro247) mFc(Pro99-Lys330) 6×His tag, Protein function: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and...
| Schlagworte: | CD86, B7-2, B70, CD28LG2, LAB72, MGC34413 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 52.4 kD |
ab 105,00 €
Human BCMA Protein, mFc Tag
Artikelnummer: DIM-PME100035.10
Recombinant human BCMA protein with C-terminal mouse Fc tag. BCMA(Met1-Ala54) mFc(Pro99-Lys330), Protein function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [The UniProt Consortium]
| Schlagworte: | TNFRSF17, CD269, BCM, BCMA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 32.1 kD |
ab 140,00 €
SARS-CoV-2 (2019-nCoV) S protein RBD, His Tag
Artikelnummer: DIM-PME100036.10
Recombinant SARS-CoV-2 (2019-nCoV) S protein RBD with C-terminal 6×His tag. S protein RBD(Arg319-Phe541) 6×His tag, Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2 (PubMed:32142651,...
| Schlagworte: | S protein RBD, Spike glycoprotein Receptor-binding domain, S glycoprotein RBD, Spike protein RBD, COVID-19 |
| Exprimiert in: | Human cells |
| Ursprungsart: | SARS-CoV-2 |
| MW: | 37-38 kD |
ab 124,00 €
Human CD19 Protein, hFc-His tag
Artikelnummer: DIM-PME100038.10
Recombinant human CD19 Protein with C-terminal Human Fc and 6×His tag. CD19(Pro20-Lys291) hFc(Glu99-Ala330) 6×His tag, Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering...
| Schlagworte: | CD19, B4, CVID3, MGC12802 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 57.1 kD |
ab 124,00 €
Human CD33(18-259) Protein, hFc-His Tag
Artikelnummer: DIM-PME100039.10
Recombinant human CD33 protein with C-terminal human Fc and 6×His tag. CD33(Asp18-His259) hFc(Glu99-Ala330) 6×His tag, Protein function: Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state (PubMed:10611343,...
| Schlagworte: | CD33, SIGLEC3, gp67 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 53.8 kD |
ab 114,00 €