Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human BCMA Protein, hFc-His Tag
Artikelnummer: DIM-PME100001.10
Recombinant human BCMA protein with C-terminal human Fc and 6×His tag. BCMA(Leu2-Ala54) hFc(Glu99-Ala330) 6×His tag, Protein function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [The UniProt...
| Schlagworte: | TNFRSF17, CD269, BCM, BCMA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 32.7 kD |
ab 120,00 €
Human CS1 Protein, hFc-His Tag
Artikelnummer: DIM-PME100002.10
Recombinant human CS1 protein with C-terminal human Fc and 6×His tag. CS1(Ser23-Asp223) hFc(Glu99-Ala330) 6×His tag, Protein function: Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances...
| Schlagworte: | SLAMF7, CD319, CS1, CRACC, 19A, FOAP-12 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 70 kD |
ab 120,00 €
Human CD123 Protein, hFc-His Tag
Artikelnummer: DIM-PME100003.10
Recombinant human CD123 protein with C-terminal human Fc and 6×His tag. CD123(Thr19-Arg305) hFc(Glu99-Ala330) 6×His tag, Protein function: This is a receptor for interleukin-3. [The UniProt Consortium]
| Schlagworte: | IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 80-90 kD |
ab 114,00 €
Human CD38 Protein, hFc-His Tag
Artikelnummer: DIM-PME100004.10
Recombinant human CD38 protein with C-terminal human Fc and 6×His tag. CD38(Val43-Ile300) hFc(Glu99-Ala330) 6×His tag, Protein function: Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has...
| Schlagworte: | CD38, T10, cADPr hydrolase 1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 70-72 kD |
ab 114,00 €
Human CD22 Protein, hFc-His Tag
Artikelnummer: DIM-PME100005.10
Recombinant human CD22 protein with C-terminal human Fc and 6×His tag. CD22(Asp20-Arg687) hFc(Glu99-Ala330) 6×His tag, Protein function: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds...
| Schlagworte: | CD22, SIGLEC2, BL-CAM, SIGLEC-2, Siglec2, SIGLEC2FLJ22814 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 102.1 kD |
ab 120,00 €
Human CD138 Protein, hFc-His Tag
Artikelnummer: DIM-PME100006.10
Recombinant human CD138 protein with C-terminal human Fc and 6×His tag. CD138(Gln23-Gly254) hFc(Glu99-Ala330) 6×His tag, Protein function: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in...
| Schlagworte: | SDC1, Syndecan-1, CD138, SYND1, SDC |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 50.8 kD |
ab 120,00 €
Human FLT3 Protein, hFc-His Tag
Artikelnummer: DIM-PME100007.10
Recombinant human FLT3 protein with C-terminal human Fc and 6×His tag. FLT3(Asn27-Ser543) hFc(Glu99-Ala330) 6×His tag, Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and...
| Schlagworte: | Flt-3, Flk-2, STK-1, CD135, FLK2, FLT-3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 125-130 kD |
ab 120,00 €
Human CD47 Protein, mFc-His Tag
Artikelnummer: DIM-PME100008.10
Recombinant human CD47 protein with C-terminal mouse Fc and 6×His tag. CD47(Gln19-Glu141) CD47(Val198-Ala207) CD47(Ser257-Gly268) mFc(Pro99-Lys330) 6×His tag, Protein function: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an...
| Schlagworte: | CD47, MER6, IAP, OA3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 60 kD |
ab 120,00 €
Human SIRPa Protein, hFc-His Tag
Artikelnummer: DIM-PME100009.10
Recombinant Human SIRPa with C-terminal human Fc and 6×His tag. SIRPa(Glu31-Tyr373) hFc(Glu99-Ala330) 6×His tag, Protein function: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane....
| Schlagworte: | SHPS1, SIRPA, CD172A, BIT, MFR, MYD1, P84, PTPNS |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 70-98 kD |
ab 120,00 €
Human 2B4 Protein, mFc-His Tag
Artikelnummer: DIM-PME100010.10
Recombinant human 2B4 protein with C-terminal mouse Fc and 6×His tag. 2B4(Cys22-Ala216) mFc(Pro99-Lys330) 6×His tag, Protein function: Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family, its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are...
| Schlagworte: | CD244, 2B4, SLAMF4, NKR2B4, NAIL, h2B4 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 48.8 kD |
ab 114,00 €
Human 4-1BB Protein, mFc-His Tag
Artikelnummer: DIM-PME100011.10
Recombinant human 4-1BB protein with C-terminal mouse Fc and 6×His tag. 41BB(Leu24-Gln186) mFc(Pro99-Lys330) 6×His, Protein function: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. [The UniProt Consortium]
| Schlagworte: | TNFRSF9, 4-1BB, CD137, CDw137, ILA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 54-60 kD |
ab 140,00 €
Human B7-H3 Protein, mFc-His Tag
Artikelnummer: DIM-PME100012.10
Recombinant human B7-H3 protein with C-terminal mouse Fc and 6×His tag. B7-H3(Leu29-Pro245) mFc(Pro99-Lys330) 6×His, Protein function: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of...
| Schlagworte: | B7-H3, CD276, B7 homolog 3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 70-75 kD |
ab 120,00 €