Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
Mehr Informationen unter: www.dimabio.com
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-IL13RA1 antibody(DM183), Rabbit mAb
Artikelnummer: DIM-DME100183.10
Protein function: Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced...
| Schlagworte: | Anti-CD213A1, Anti-CT19, Anti-IL-13Ra, Anti-NR4, Anti-IL13RA1 antibody(DM183), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-KLRG1 antibody(DM184), Rabbit mAb
Artikelnummer: DIM-DME100184.10
Protein function: Plays an inhibitory role on natural killer (NK) cells and T- cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E- cadherin/CDH1, N-cadherin/CDH2 and...
| Schlagworte: | Anti-CLEC15A, Anti-MAFA, Anti-MAFAL, Anti-KLRG1 antibody(DM184), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-VEGFR2 antibody(DM185), Rabbit mAb
Artikelnummer: DIM-DME100185.10
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of...
| Schlagworte: | Anti-CD309, Anti-FLK1, Anti-VEGFR, Anti-VEGFR2, Anti-VEGFR2 antibody(DM185), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-AMHR2 antibody(DM186), Rabbit mAb
Artikelnummer: DIM-DME100186.10
Protein function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian...
| Schlagworte: | Anti-AMHR, Anti-MISR2, Anti-MISRII, Anti-MRII, Anti-AMHR2 antibody(DM186), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IL2 antibody(DM187), Rabbit mAb
Artikelnummer: DIM-DME100187.10
Protein function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells....
| Schlagworte: | Anti-IL-2, Anti-lymphokine, Anti-TCGF, Anti-IL2 antibody(DM187), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-B7-H4 antibody(DM188), Rabbit mAb
Artikelnummer: DIM-DME100188.10
Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in the suppression of...
| Schlagworte: | Anti-B7-H4, Anti-B7h.5, Anti-B7H4, Anti-B7S1, Anti-B7X, Anti-PRO1291, Anti-VCTN1, Anti-B7-H4 antibody(DM188), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-BCL2L1 antibody(DM189), Rabbit mAb
Artikelnummer: DIM-DME100189.10
Protein function: Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2...
| Schlagworte: | Anti-Bcl-X, Anti-BCL-XL:S, Anti-BCL2L, Anti-BCLX, Anti-PPP1R52, Anti-BCL2L1 antibody(DM189), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-PGF antibody(DM190), Rabbit mAb
Artikelnummer: DIM-DME100190.10
Protein function: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. [The UniProt Consortium]
| Schlagworte: | Anti-D12S1900, Anti-PGFL, Anti-PIGF, Anti-PLGF, Anti-PlGF-2, Anti-SHGC-10760, Anti-PGF antibody(DM190), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD70 antibody(DM191), Rabbit mAb
Artikelnummer: DIM-DME100191.10
Protein function: Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses. Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells....
| Schlagworte: | Anti-CD70, Anti-CD27LG, Anti-TNFSF7, Anti-TNFSF7G, Anti-CD27L, Anti-CD70 antibody(DM191), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-ADAM9 antibody(DM192), Rabbit mAb
Artikelnummer: DIM-DME100192.10
Protein function: Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins. [The UniProt Consortium]
| Schlagworte: | Anti-CORD9, Anti-MCMP, Anti-MDC9, Anti-Mltng, Anti-ADAM9 antibody(DM192), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD45 antibody(DM193), Rabbit mAb
Artikelnummer: DIM-DME100193.10
Protein function: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first...
| Schlagworte: | Anti-B220, Anti-CD45, Anti-CD45R, Anti-GP180, Anti-L-CA, Anti-LCA, Anti-LY5, Anti-T200, Anti-CD45 antibody(DM193), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-SCF antibody(DM194), Rabbit mAb
Artikelnummer: DIM-DME100194.10
Protein function: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several...
| Schlagworte: | Anti-DCUA, Anti-DFNA69, Anti-FPH2, Anti-FPHH, Anti-Kitl, Anti-KL-1, Anti-MGF, Anti-SCF, Anti-SF, Anti-SHEP7, Anti-SLF,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €