Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-CA9 antibody(DM171), Rabbit mAb
Artikelnummer: DIM-DME100171.10
Protein function: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. [The UniProt Consortium]
| Schlagworte: | Anti-CAIX, Anti-MN, Anti-CA9 antibody(DM171), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD114 antibody(DM172), Rabbit mAb
Artikelnummer: DIM-DME100172.10
Protein function: Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface....
| Schlagworte: | Anti-CSF3R, Anti-CD114, Anti-GCSFR, Anti-CD114 antibody(DM172), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-B7-H6 antibody(DM173), Rabbit mAb
Artikelnummer: DIM-DME100173.10
Protein function: Triggers NCR3-dependent natural killer cell activation. [The UniProt Consortium]
| Schlagworte: | Anti-B7-H6, Anti-NCR3LG1, Anti-B7 Homolog 6, Anti-B7-H6 antibody(DM173), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-ROR2 antibody(DM174), Rabbit mAb
Artikelnummer: DIM-DME100174.10
Protein function: Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to...
| Schlagworte: | Anti-ROR2, Anti-NTRKR2, Anti-ROR2 antibody(DM174), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-Her3 antibody(DM175), Rabbit mAb
Artikelnummer: DIM-DME100175.10
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase...
| Schlagworte: | Anti-HER3, Anti-ERBB3, Anti-Her3 antibody(DM175), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD10 antibody(DM176), Rabbit mAb
Artikelnummer: DIM-DME100176.10
Protein function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave...
| Schlagworte: | Anti-MME, Anti-CALLA, Anti-CD10, Anti-DKFZp686O16152, Anti-MGC126681, Anti-MGC126707, Anti-NEP, Anti-SFE, Anti-Neprilysin,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-PD-1 antibody(DM177), Rabbit mAb
Artikelnummer: DIM-DME100177.10
Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell receptor (TCR) engagement,...
| Schlagworte: | Anti-PDCD1, Anti-PD1, Anti-CD279, Anti-SLEB2, Anti-PD-1 antibody(DM177), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TIGIT antibody(DM178), Rabbit mAb
Artikelnummer: DIM-DME100178.10
Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Schlagworte: | Anti-TIGIT, Anti-VSIG9, Anti-VSTM3, Anti-TIGIT antibody(DM178), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CLDN18.2 antibody(DM179), Rabbit mAb
Artikelnummer: DIM-DME100179.10
Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [The UniProt Consortium]
| Schlagworte: | Anti-Claudin 18.2, Anti-CLDN18.2 antibody(DM179), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CCR8 antibody(DM180), Rabbit mAb
Artikelnummer: DIM-DME100180.10
Protein function: Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. [The UniProt Consortium]
| Schlagworte: | Anti-CC-CKR-8, Anti-CCR-8, Anti-CDw198, Anti-CKRL1, Anti-CMKBR8, Anti-CMKBRL2, Anti-CY6, Anti-GPRCY6, Anti-TER1, Anti-CCR8... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-BAFF antibody(DM181), Rabbit mAb
Artikelnummer: DIM-DME100181.10
Protein function: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T- cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3)...
| Schlagworte: | Anti-TNFSF13B, Anti-BAFF, Anti-BLYS, Anti-CD257, Anti-DTL, Anti-TALL1, Anti-THANK, Anti-TNFSF20, Anti-ZTNF4, Anti-TALL-1,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-BTLA antibody(DM182), Rabbit mAb
Artikelnummer: DIM-DME100182.10
Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis...
| Schlagworte: | Anti-BTLA, Anti-CD272, Anti-BTLA antibody(DM182), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €