Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-AXL antibody(DM158), Rabbit mAb
Artikelnummer: DIM-DME100158.10
Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at the cell surface...
| Schlagworte: | Anti-AXL, Anti-UFO, Anti-AXL antibody(DM158), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-NTB-A antibody(DM159), Rabbit mAb
Artikelnummer: DIM-DME100159.10
Protein function: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and...
| Schlagworte: | Anti-NTB-A, Anti-SLAMF6, Anti-Ly108, Anti-NK-T-B-antigen, Anti-CD352, Anti-KALI, Anti-NTB-A antibody(DM159), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-LAG3 antibody(DM160), Rabbit mAb
Artikelnummer: DIM-DME100160.10
Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell inhibitory...
| Schlagworte: | Anti-LAG-3, Anti-CD223, Anti-LAG3 antibody(DM160), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD5 antibody(DM161), Rabbit mAb
Artikelnummer: DIM-DME100161.10
Protein function: May act as a receptor in regulating T-cell proliferation. [The UniProt Consortium]
| Schlagworte: | Anti-CD5, Anti-LEU1, Anti-CD5 antibody(DM161), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-EPHA3 antibody(DM162), Rabbit mAb
Artikelnummer: DIM-DME100162.10
Protein function: Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling...
| Schlagworte: | Anti-TYRO4, Anti-HEK4, Anti-ETK1, Anti-ETK, Anti-EK4, Anti-HEK, Anti-EPHA3 antibody(DM162), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD40 Ligand antibody(DM164), Rabbit mAb
Artikelnummer: DIM-DME100164.10
Protein function: Cytokine that acts as a ligand to CD40/TNFRSF5 (PubMed:1280226, PubMed:31331973). Costimulates T-cell proliferation and cytokine production (PubMed:8617933). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3...
| Schlagworte: | Anti-CD40LG, Anti-CD154, Anti-CD40L, Anti-HIGM1, Anti-IGM, Anti-IMD3, Anti-T-BAM, Anti-TNFSF5, Anti-TRAP, Anti-gp39,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CLEC12A antibody(DM165), Rabbit mAb
Artikelnummer: DIM-DME100165.10
Protein function: Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. [The UniProt Consortium]
| Schlagworte: | Anti-CLEC12A, Anti-MICL, Anti-CLL-1, Anti-CLL1, Anti-DCAL2, Anti-DCAL-2, Anti-CD371, Anti-CLEC12A antibody(DM165), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD37 antibody(DM166), Rabbit mAb
Artikelnummer: DIM-DME100166.10
| Schlagworte: | Anti-CD37, Anti-TSPAN26, Anti-Tspan-26, Anti-CD37 antibody(DM166), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-EPHA2 antibody(DM167), Rabbit mAb
Artikelnummer: DIM-DME100167.10
Protein function: Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the...
| Schlagworte: | Anti-ARCC2, Anti-CTPA, Anti-CTPP1, Anti-CTRCT6, Anti-ECK, Anti-EPHA2 antibody(DM167), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-MICB antibody(DM168), Rabbit mAb
Artikelnummer: DIM-DME100168.10
Protein function: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. [The UniProt Consortium]
| Schlagworte: | Anti-MIC-B, Anti-PERB11.2, Anti-MICB antibody(DM168), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-PDL2 antibody(DM169), Rabbit mAb
Artikelnummer: DIM-DME100169.10
Protein function: Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [The UniProt Consortium]
| Schlagworte: | Anti-B7DC, Anti-bA574F11.2, Anti-Btdc, Anti-CD273, Anti-PD-L2, Anti-PDCD1L2, Anti-PDL2, Anti-PDL2 antibody(DM169), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-LIGHT antibody(DM170), Rabbit mAb
Artikelnummer: DIM-DME100170.10
Protein function: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM (PubMed:9462508, PubMed:10754304). Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production...
| Schlagworte: | Anti-TNFSF14, Anti-CD258, Anti-HVEML, Anti-LIGHT, Anti-LTg, Anti-LIGHT antibody(DM170), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €