Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-EGFR antibody(DM130), Rabbit mAb
Artikelnummer: DIM-DME100130.10
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Schlagworte: | Anti-EGFR, Anti-ERBB, Anti-ERBB1, Anti-HER1, Anti-PIG61, Anti-mENA, Anti-EGFR antibody(DM130), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-HVEM antibody(DM131), Rabbit mAb
Artikelnummer: DIM-DME100131.10
Protein function: Receptor for four distinct ligands: The TNF superfamily members TNFSF14/LIGHT and homotrimeric LTA/lymphotoxin-alpha and the immunoglobulin superfamily members BTLA and CD160, altogether defining a complex stimulatory and inhibitory signaling network (PubMed:9462508, PubMed:10754304,...
| Schlagworte: | Anti-ATAR, Anti-CD270, Anti-HVEA, Anti-HVEM, Anti-LIGHTR, Anti-TR2, Anti-HVEM antibody(DM131), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-HVEM antibody(DM132), Rabbit mAb
Artikelnummer: DIM-DME100132.10
Protein function: Receptor for four distinct ligands: The TNF superfamily members TNFSF14/LIGHT and homotrimeric LTA/lymphotoxin-alpha and the immunoglobulin superfamily members BTLA and CD160, altogether defining a complex stimulatory and inhibitory signaling network (PubMed:9462508, PubMed:10754304,...
| Schlagworte: | Anti-ATAR, Anti-CD270, Anti-HVEA, Anti-HVEM, Anti-LIGHTR, Anti-TR2, Anti-HVEM antibody(DM132), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-HVEM antibody(DM133), Rabbit mAb
Artikelnummer: DIM-DME100133.10
Protein function: Receptor for four distinct ligands: The TNF superfamily members TNFSF14/LIGHT and homotrimeric LTA/lymphotoxin-alpha and the immunoglobulin superfamily members BTLA and CD160, altogether defining a complex stimulatory and inhibitory signaling network (PubMed:9462508, PubMed:10754304,...
| Schlagworte: | Anti-ATAR, Anti-CD270, Anti-HVEA, Anti-HVEM, Anti-LIGHTR, Anti-TR2, Anti-HVEM antibody(DM133), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD34 antibody(DM134), Rabbit mAb
Artikelnummer: DIM-DME100134.10
Protein function: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by...
| Schlagworte: | Anti-CD34, Anti-CD34 antibody(DM134), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD34 antibody(DM135), Rabbit mAb
Artikelnummer: DIM-DME100135.10
Protein function: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by...
| Schlagworte: | Anti-CD34, Anti-CD34 antibody(DM135), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD34 antibody(DM136), Rabbit mAb
Artikelnummer: DIM-DME100136.10
Protein function: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by...
| Schlagworte: | Anti-CD34, Anti-CD34 antibody(DM136), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-5T4 antibody(DM137), Rabbit mAb
Artikelnummer: DIM-DME100137.10
Protein function: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. [The UniProt Consortium]
| Schlagworte: | Anti-5T4, Anti-5T4 antibody(DM137), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-5T4 antibody(DM138), Rabbit mAb
Artikelnummer: DIM-DME100138.10
Protein function: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. [The UniProt Consortium]
| Schlagworte: | Anti-5T4, Anti-5T4 antibody(DM138), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-5T4 antibody(DM139), Rabbit mAb
Artikelnummer: DIM-DME100139.10
Protein function: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. [The UniProt Consortium]
| Schlagworte: | Anti-5T4, Anti-5T4 antibody(DM139), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TNFSF12 antibody(DM140), Rabbit mAb
Artikelnummer: DIM-DME100140.10
Protein function: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion. [The UniProt Consortium]
| Schlagworte: | Anti-TNFSF12, Anti-TNFSF12 antibody(DM140), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TNFSF12 antibody(DM141), Rabbit mAb
Artikelnummer: DIM-DME100141.10
Protein function: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion. [The UniProt Consortium]
| Schlagworte: | Anti-TNFSF12, Anti-TNFSF12 antibody(DM141), Rabbit mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €