Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-FCRL5 antibody(DMC220), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100220.10
Protein function: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. [The UniProt Consortium]
| Schlagworte: | Anti-BXMAS1, Anti-CD307, Anti-CD307e, Anti-FCRH5, Anti-IRTA2, Anti-PRO820, Anti-FCRL5 antibody(DMC220), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IFNAR1 antibody(DMC221), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100221.10
Protein function: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986)....
| Schlagworte: | Anti-Interferon alpha:beta receptor 1, Anti-IFN-R-1, Anti-IFN-alpha:beta receptor 1, Anti-CRF2-1, Anti-Type I interferon... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-PCSK9 antibody(DMC222), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100222.10
Protein function: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and...
| Schlagworte: | Anti-FH3, Anti-FHCL3, Anti-HCHOLA3, Anti-LDLCQ1, Anti-NARC-1, Anti-NARC1, Anti-PC9, Anti-PCSK9 antibody(DMC222), IgG1... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TREM2 antibody(DMC223), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100223.10
Protein function: Forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia...
| Schlagworte: | Anti-PLOSL2, Anti-TREM-2, Anti-Trem2a, Anti-Trem2b, Anti-Trem2c, Anti-TREM2 antibody(DMC223), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD112 antibody(DMC224), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100224.10
Protein function: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG,...
| Schlagworte: | Anti-NECTIN2, Anti-HVEB, Anti-PRR2, Anti-PVRL2, Anti-PVRR2, Anti-CD112 antibody(DMC224), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-IL21R antibody(DMC225), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100225.10
Protein function: This is a receptor for interleukin-21. [The UniProt Consortium]
| Schlagworte: | Anti-CD360, Anti-IMD56, Anti-NILR, Anti-IL21R antibody(DMC225), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-ROR1 antibody(151A5), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100228.10
Protein function: Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443, PubMed:27162350). In inner ear,...
| Schlagworte: | Anti-ROR1, Anti-NTRKR1, Anti-ROR1 antibody(151A5), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-ROR1 antibody(172B7), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100253.10
Protein function: Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443, PubMed:27162350). In inner ear,...
| Schlagworte: | Anti-ROR1, Anti-NTRKR1, Anti-ROR1 antibody(172B7), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-TNFSF11 antibody(DMC267), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100267.10
Protein function: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the...
| Schlagworte: | Anti-CD254, Anti-hRANKL2, Anti-ODF, Anti-OPGL, Anti-OPTB2, Anti-RANKL, Anti-sOdf, Anti-TNLG6B, Anti-TRANCE, Anti-TNFSF11... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-VSIG4 antibody(DMC268), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100268.10
Protein function: Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. [The UniProt Consortium]
| Schlagworte: | Anti-CRIg, Anti-Z39IG, Anti-VSIG4 antibody(DMC268), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD44 antibody(DMC269), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100269.10
Protein function: Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment (PubMed:16541107, PubMed:19703720, PubMed:22726066). Participates thereby in a wide variety of cellular functions including the...
| Schlagworte: | Anti-CD44, Anti-CDW44, Anti-CSPG8, Anti-ECMR-III, Anti-HCELL, Anti-HUTCH-I, Anti-IN, Anti-LHR, Anti-MC56, Anti-MDU2,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD160 antibody(DMC270), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100270.10
Protein function: [CD160 antigen]: Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK...
| Schlagworte: | Anti-BY55, Anti-NK1, Anti-NK28, Anti-CD160 antibody(DMC270), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €