Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
Mehr Informationen unter: www.dimabio.com
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-ACVR2B(bimagrumab biosimilar) mAb
Artikelnummer: DIM-BME100228.100
Protein function: Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and...
| Schlagworte: | Anti-AVR2B, Anti-ACTR-IIB, Anti-ACVR2B(bimagrumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-NKG2D(5C5 biosimilar, L234A/L235A) mAb
Artikelnummer: DIM-BME100229.100
Protein function: Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on...
| Schlagworte: | Anti-NKG2D, Anti-CD314, Anti-KLRK1, Anti-NK cell receptor D, Anti-NKG2D(5C5 biosimilar, L234A/L235A) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-ADAM9(izeltabart biosimilar) mAb
Artikelnummer: DIM-BME100230.100
Protein function: Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins. [The UniProt Consortium]
| Schlagworte: | Anti-CORD9, Anti-MCMP, Anti-MDC9, Anti-Mltng, Anti-ADAM9(izeltabart biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL31RA(nemolizumab biosimilar) mAb
Artikelnummer: DIM-BME100231.100
Protein function: Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on...
| Schlagworte: | Anti-CRL, Anti-GPL, Anti-CRL3, Anti-GLMR, Anti-GLM-R, Anti-PLCA2, Anti-hGLM-R, Anti-IL-31RA, Anti-PRO21384, Anti-zcytoR17,... |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CDH6(raludotatug biosimilar) mAb
Artikelnummer: DIM-BME100232.100
Protein function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. [The UniProt Consortium]
| Schlagworte: | Anti-CADH6, Anti-K-cadherin, Anti-CDH6(raludotatug biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CDH17(TORL-3-600 biosimilar) mAb
Artikelnummer: DIM-BME100233.100
Protein function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and...
| Schlagworte: | Anti-Cadherin-17, Anti-CDH17(TORL-3-600 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL10(BT 063 biosimilar) mAb
Artikelnummer: DIM-BME100254.100
Protein function: Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and...
| Schlagworte: | Anti-IL-10, Anti-CSIF, Anti-IL10(BT 063 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-BCMA bispecific antibody(DM4)
Artikelnummer: DIM-DMB100003.10
Protein function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [The UniProt Consortium]
| Schlagworte: | Anti-TNFRSF17, Anti-BCMA bispecific antibody(DM4) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CEACAM5 antibody(1B5), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100120.10
Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6...
| Schlagworte: | Anti-CEACAM-5, Anti-CD66e, Anti-CEA, Anti-Meconium antigen 100, Anti-CEACAM5 antibody(1B5), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD24 antibody(DMC213), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100213.10
Protein function: May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin- like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes...
| Schlagworte: | Anti-CD24A, Anti-CD24 antibody(DMC213), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-CD24 antibody(DMC217), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100217.10
Protein function: May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin- like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes...
| Schlagworte: | Anti-CD24A, Anti-CD24 antibody(DMC217), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Anti-FCGR3A antibody(DMC219), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100219.10
Protein function: Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. [The UniProt Consortium]
| Schlagworte: | Anti-FCGR3A, Anti-CD16A, Anti-FCG3, Anti-FCGR3, Anti-IGFR3, Anti-FCGR3A antibody(DMC219), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €